TY - JOUR T1 - Characteristics, complications and outcomes among 1549 patients hospitalised with COVID-19 in a secondary hospital in Madrid, Spain: a retrospective case series study. AU - Jiménez,Eva, AU - Fontán-Vela,Mario, AU - Valencia,Jorge, AU - Fernandez-Jimenez,Ines, AU - Álvaro-Alonso,Elena Alba, AU - Izquierdo-García,Elsa, AU - Lazaro Cebas,Andrea, AU - Gallego Ruiz-Elvira,Elisa, AU - Troya,Jesús, AU - Tebar-Martinez,Ana Josefa, AU - Garcia-Marina,Belén, AU - Peña-Lillo,Gabriela, AU - Abad-Motos,Ane, AU - Macaya,Laura, AU - Ryan,Pablo, AU - Pérez-Butragueño,Mario, AU - ,, AU - ,, Y1 - 2020/11/10/ PY - 2020/11/11/entrez PY - 2020/11/12/pubmed PY - 2020/11/20/medline KW - COVID-19 KW - epidemiology KW - infectious diseases KW - public health SP - e042398 EP - e042398 JF - BMJ open JO - BMJ Open VL - 10 IS - 11 N2 - OBJECTIVES: To describe demographic, clinical, radiological and laboratory characteristics, as well as outcomes, of patients admitted for COVID-19 in a secondary hospital. DESIGN AND SETTING: Retrospective case series of sequentially hospitalised patients with confirmed SARS-CoV-2, at Infanta Leonor University Hospital (ILUH) in Madrid, Spain. PARTICIPANTS: All patients attended at ILUH testing positive to reverse transcriptase-PCR on nasopharyngeal swabs and diagnosed with COVID-19 between 1 March 2020 and 28 May 2020. RESULTS: A total of 1549 COVID-19 cases were included (median age 69 years (IQR 55.0-81.0), 57.5% men). 78.2% had at least one underlying comorbidity, the most frequent was hypertension (55.8%). Most frequent symptoms at presentation were fever (75.3%), cough (65.7%) and dyspnoea (58.1%). 81 (5.8%) patients were admitted to the intensive care unit (ICU) (median age 62 years (IQR 51-71); 74.1% men; median length of stay 9 days (IQR 5-19)) 82.7% of them needed invasive ventilation support. 1393 patients had an outcome at the end of the study period (case fatality ratio: 21.2% (296/1393)). The independent factors associated with fatality (OR; 95% CI): age (1.07; 1.06 to 1.09), male sex (2.86; 1.85 to 4.50), neurological disease (1.93; 1.19 to 3.13), chronic kidney disease (2.83; 1.40 to 5.71) and neoplasia (4.29; 2.40 to 7.67). The percentage of hospital beds occupied with COVID-19 almost doubled (702/361), with the number of patients in ICU quadrupling its capacity (32/8). Median length of stay was 9 days (IQR 6-14). CONCLUSIONS: This study provides clinical characteristics, complications and outcomes of patients with COVID-19 admitted to a European secondary hospital. Fatal outcomes were similar to those reported by hospitals with a higher level of complexity. SN - 2044-6055 UR - https://www.unboundmedicine.com/medline/citation/33172949/Characteristics_complications_and_outcomes_among_1549_patients_hospitalised_with_COVID_19_in_a_secondary_hospital_in_Madrid_Spain:_a_retrospective_case_series_study_ L2 - https://bmjopen.bmj.com/lookup/pmidlookup?view=long&pmid=33172949 DB - PRIME DP - Unbound Medicine ER -