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18F-FDG PET/CT in Initial Diagnosis and Treatment Response Evaluation of Anti-NMDAr and Anti-GAD Dual Antibody Autoimmune Encephalitis.
Clin Nucl Med. 2021 Jan; 46(1):e63-e64.CN

Abstract

We report a case of 34-year-old woman presenting with complaints of abnormal posturing of hand and tonic-clonic seizures of few days' duration, which soon progressed to psychotic episodes and injuries secondary to fall/abnormal movements. She underwent F-FDG PET for a suspicion of encephalitis, which revealed increased FDG uptake in the bilateral parietotemporal lobes (right more than left), anterior cingulate cortex, bilateral basal ganglia, thalami, and cerebellum. This atypical pattern did not conform to any known pattern of encephalitis, which was later attributed to the presence of both anti-NMDAr and anti-GAD antibodies in blood and cerebrospinal fluid.

Authors+Show Affiliations

From the Department of Nuclear Medicine and PET/CT, Mahajan Imaging Centre.From the Department of Nuclear Medicine and PET/CT, Mahajan Imaging Centre.Department of Neurology, Sir Ganga Ram Hospital, New Delhi, India.From the Department of Nuclear Medicine and PET/CT, Mahajan Imaging Centre.From the Department of Nuclear Medicine and PET/CT, Mahajan Imaging Centre.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

33181746

Citation

Seniaray, Nikhil, et al. "18F-FDG PET/CT in Initial Diagnosis and Treatment Response Evaluation of Anti-NMDAr and Anti-GAD Dual Antibody Autoimmune Encephalitis." Clinical Nuclear Medicine, vol. 46, no. 1, 2021, pp. e63-e64.
Seniaray N, Verma R, Ranjan R, et al. 18F-FDG PET/CT in Initial Diagnosis and Treatment Response Evaluation of Anti-NMDAr and Anti-GAD Dual Antibody Autoimmune Encephalitis. Clin Nucl Med. 2021;46(1):e63-e64.
Seniaray, N., Verma, R., Ranjan, R., Belho, E., & Mahajan, H. (2021). 18F-FDG PET/CT in Initial Diagnosis and Treatment Response Evaluation of Anti-NMDAr and Anti-GAD Dual Antibody Autoimmune Encephalitis. Clinical Nuclear Medicine, 46(1), e63-e64. https://doi.org/10.1097/RLU.0000000000003379
Seniaray N, et al. 18F-FDG PET/CT in Initial Diagnosis and Treatment Response Evaluation of Anti-NMDAr and Anti-GAD Dual Antibody Autoimmune Encephalitis. Clin Nucl Med. 2021;46(1):e63-e64. PubMed PMID: 33181746.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - 18F-FDG PET/CT in Initial Diagnosis and Treatment Response Evaluation of Anti-NMDAr and Anti-GAD Dual Antibody Autoimmune Encephalitis. AU - Seniaray,Nikhil, AU - Verma,Ritu, AU - Ranjan,Rajeev, AU - Belho,Ethel, AU - Mahajan,Harsh, PY - 2020/11/13/pubmed PY - 2020/12/29/medline PY - 2020/11/12/entrez SP - e63 EP - e64 JF - Clinical nuclear medicine JO - Clin Nucl Med VL - 46 IS - 1 N2 - We report a case of 34-year-old woman presenting with complaints of abnormal posturing of hand and tonic-clonic seizures of few days' duration, which soon progressed to psychotic episodes and injuries secondary to fall/abnormal movements. She underwent F-FDG PET for a suspicion of encephalitis, which revealed increased FDG uptake in the bilateral parietotemporal lobes (right more than left), anterior cingulate cortex, bilateral basal ganglia, thalami, and cerebellum. This atypical pattern did not conform to any known pattern of encephalitis, which was later attributed to the presence of both anti-NMDAr and anti-GAD antibodies in blood and cerebrospinal fluid. SN - 1536-0229 UR - https://www.unboundmedicine.com/medline/citation/33181746/18F_FDG_PET/CT_in_Initial_Diagnosis_and_Treatment_Response_Evaluation_of_Anti_NMDAr_and_Anti_GAD_Dual_Antibody_Autoimmune_Encephalitis_ L2 - https://dx.doi.org/10.1097/RLU.0000000000003379 DB - PRIME DP - Unbound Medicine ER -