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Prevalence of obesity and hypovitaminosis D in elderly with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Clin Nutr ESPEN. 2020 12; 40:110-114.CN

Abstract

BACKGROUND & AIM

Verify the prevalence of hypovitaminosis D and obesity in elderly patients infected by new coronavirus. The patients developed severe symptoms and were admitted in intensive care unit (ICU) to receive invasive ventilation due to diagnosis of acute respiratory distress syndrome (ARDS).

METHODS

A cross-sectional descriptive study composed of elderly (age ≥ 60 years) admitted to the ICU. Were collected demographic (sex, age), anthropometric data, presence of comorbidities (hypertension, diabetes, heart disease, lung, neurological and oncological diseases), severity score in ICU (SAPS III), PaO2/FiO2 ratio, analysis of C-reactive protein (CRP) and serum dosage of 25-hydroxy vitamin D (25 OHD) in the first day of hospitalization to identify elderly with hypovitaminosis D (low values < 30 ng/mL). The diagnosis of obesity in elderly was determined by calculating the body mass index (BMI) ≥ 30 kg/m2.

RESULTS

A total of 176 elderly met the inclusion criteria. 54% were elderly men and mean age of 72.9 ± 9.1 years. The median BMI was 30.5 (28.1-33) kg/m2 with 68.7% having a nutritional diagnosis of obesity and 15.3% had BMI ≥ 35 kg/m2. The most prevalent comorbidities were hypertension (72.2%) and diabetes (40.9%). Prevalence of hypovitaminosis D with values of 25 OHD <30 ng/mL, < 20 ng/mL and <10 ng/mL was 93.8%, 65.9% and 21% respectively. The prevalence of hypovitaminosis D (<30 ng/mL) in obese elderly was 94.2%. There was a negative and significant bivariate correlation between BMI and levels of 25 OHD (r = - 0.15; p = 0.04).

CONCLUSION

Hypovitaminosis D and obesity in elderly have a high prevalence in critically ill patients in ICU infected by the new coronavirus. Laboratory investigation of vitamin D becomes important, especially in obese elderly patients.

Authors+Show Affiliations

Sancta Maggiore Hospital, Prevent Senior Private Health Operator, São Paulo, Brazil. Electronic address: thiagojmg@yahoo.com.br.Sancta Maggiore Hospital, Prevent Senior Private Health Operator, São Paulo, Brazil.Sancta Maggiore Hospital, Prevent Senior Private Health Operator, São Paulo, Brazil.Sancta Maggiore Hospital, Prevent Senior Private Health Operator, São Paulo, Brazil.Sancta Maggiore Hospital, Prevent Senior Private Health Operator, São Paulo, Brazil.Sancta Maggiore Hospital, Prevent Senior Private Health Operator, São Paulo, Brazil.Sancta Maggiore Hospital, Prevent Senior Private Health Operator, São Paulo, Brazil.Sancta Maggiore Hospital, Prevent Senior Private Health Operator, São Paulo, Brazil.Sancta Maggiore Hospital, Prevent Senior Private Health Operator, São Paulo, Brazil.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

33183522

Citation

Gonçalves, Thiago José Martins, et al. "Prevalence of Obesity and Hypovitaminosis D in Elderly With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)." Clinical Nutrition ESPEN, vol. 40, 2020, pp. 110-114.
Gonçalves TJM, Gonçalves SEAB, Guarnieri A, et al. Prevalence of obesity and hypovitaminosis D in elderly with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Clin Nutr ESPEN. 2020;40:110-114.
Gonçalves, T. J. M., Gonçalves, S. E. A. B., Guarnieri, A., Risegato, R. C., Guimarães, M. P., de Freitas, D. C., Razuk-Filho, A., Benedito Junior, P. B., & Parrillo, E. F. (2020). Prevalence of obesity and hypovitaminosis D in elderly with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Clinical Nutrition ESPEN, 40, 110-114. https://doi.org/10.1016/j.clnesp.2020.10.008
Gonçalves TJM, et al. Prevalence of Obesity and Hypovitaminosis D in Elderly With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Clin Nutr ESPEN. 2020;40:110-114. PubMed PMID: 33183522.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence of obesity and hypovitaminosis D in elderly with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). AU - Gonçalves,Thiago José Martins, AU - Gonçalves,Sandra Elisa Adami Batista, AU - Guarnieri,Andreia, AU - Risegato,Rodrigo Cristovão, AU - Guimarães,Maysa Penteado, AU - de Freitas,Daniella Cabral, AU - Razuk-Filho,Alvaro, AU - Benedito Junior,Pedro Batista, AU - Parrillo,Eduardo Fagundes, Y1 - 2020/10/13/ PY - 2020/05/27/received PY - 2020/09/19/revised PY - 2020/10/07/accepted PY - 2020/11/13/entrez PY - 2020/11/14/pubmed PY - 2020/11/21/medline KW - COVID-19 KW - Elderly KW - ICU KW - Obesity KW - SARS-CoV-2 KW - Vitamin D SP - 110 EP - 114 JF - Clinical nutrition ESPEN JO - Clin Nutr ESPEN VL - 40 N2 - BACKGROUND & AIM: Verify the prevalence of hypovitaminosis D and obesity in elderly patients infected by new coronavirus. The patients developed severe symptoms and were admitted in intensive care unit (ICU) to receive invasive ventilation due to diagnosis of acute respiratory distress syndrome (ARDS). METHODS: A cross-sectional descriptive study composed of elderly (age ≥ 60 years) admitted to the ICU. Were collected demographic (sex, age), anthropometric data, presence of comorbidities (hypertension, diabetes, heart disease, lung, neurological and oncological diseases), severity score in ICU (SAPS III), PaO2/FiO2 ratio, analysis of C-reactive protein (CRP) and serum dosage of 25-hydroxy vitamin D (25 OHD) in the first day of hospitalization to identify elderly with hypovitaminosis D (low values < 30 ng/mL). The diagnosis of obesity in elderly was determined by calculating the body mass index (BMI) ≥ 30 kg/m2. RESULTS: A total of 176 elderly met the inclusion criteria. 54% were elderly men and mean age of 72.9 ± 9.1 years. The median BMI was 30.5 (28.1-33) kg/m2 with 68.7% having a nutritional diagnosis of obesity and 15.3% had BMI ≥ 35 kg/m2. The most prevalent comorbidities were hypertension (72.2%) and diabetes (40.9%). Prevalence of hypovitaminosis D with values of 25 OHD <30 ng/mL, < 20 ng/mL and <10 ng/mL was 93.8%, 65.9% and 21% respectively. The prevalence of hypovitaminosis D (<30 ng/mL) in obese elderly was 94.2%. There was a negative and significant bivariate correlation between BMI and levels of 25 OHD (r = - 0.15; p = 0.04). CONCLUSION: Hypovitaminosis D and obesity in elderly have a high prevalence in critically ill patients in ICU infected by the new coronavirus. Laboratory investigation of vitamin D becomes important, especially in obese elderly patients. SN - 2405-4577 UR - https://www.unboundmedicine.com/medline/citation/33183522/Prevalence_of_obesity_and_hypovitaminosis_D_in_elderly_with_severe_acute_respiratory_syndrome_coronavirus_2__SARS_CoV_2__ L2 - https://linkinghub.elsevier.com/retrieve/pii/S2405-4577(20)31053-6 DB - PRIME DP - Unbound Medicine ER -