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Epidemiological and clinical characteristics of 2019 novel coronavirus disease (COVID-19) in Jilin, China: A descriptive study.
Medicine (Baltimore). 2020 Nov 20; 99(47):e23407.M

Abstract

Coronavirus diseases 2019 (COVID-19) has become a global pandemic. To add to the scarce information on this disease, here, we investigated the epidemiological and clinical characteristics of 93 hospitalized patients with COVID-19 in Jilin, China from January 22 to March 15, 2020.We retrospectively investigated the demographic information, recent exposure history, clinical symptoms or signs, comorbidity, chest computed tomographic (CT) scan or X-ray results, laboratory test results, diagnostic classification, treatment, length of hospitalization, complications, and outcomes.Of the 93 patients, 54 were male and 39 female. More than half of these patients had a history of exposure to infected patients. The mean incubation period was 10.4 days in 87 patients, where the data was available. The 5 most common symptoms of illness onset were fever, cough, expectoration, fatigue, and dyspnea. One patient was asymptomatic. The imaging results were abnormal in majority of the patients. Almost one-third of the patients had lymphopenia. All patients received antiviral therapy, 84 patients were treated with antibiotics and 54 received different doses of the hormone for methylprednisolone. In addition, 72 patients used traditional Chinese medicine. Oxygen therapy, high nasal flow oxygen, non-invasive ventilator, invasive ventilator and extracorporeal membrane oxygenation (ECMO) were used symptomatically in different patients. Except 1 patient who died during treatment, all others were discharged.The average incubation time is prolonged in the present analysis, as compared to that in other reports. A few patients symptoms improved but CT exacerbated. Therefore, we suggest that close follow-up observation is still required after discharge.

Authors+Show Affiliations

Department of Respiratory Medicine, Key Laboratory of Organ Regeneration & Transplantation of the Ministry of Education, the First Hospital of Jilin University, Changchun, PR China.Department of Respiratory Medicine, Key Laboratory of Organ Regeneration & Transplantation of the Ministry of Education, the First Hospital of Jilin University, Changchun, PR China.Department of Respiratory Medicine, Key Laboratory of Organ Regeneration & Transplantation of the Ministry of Education, the First Hospital of Jilin University, Changchun, PR China.Department of Respiratory Medicine, Key Laboratory of Organ Regeneration & Transplantation of the Ministry of Education, the First Hospital of Jilin University, Changchun, PR China.Department of Respiratory Medicine, Key Laboratory of Organ Regeneration & Transplantation of the Ministry of Education, the First Hospital of Jilin University, Changchun, PR China.Department of Respiratory Medicine, Key Laboratory of Organ Regeneration & Transplantation of the Ministry of Education, the First Hospital of Jilin University, Changchun, PR China. Department of Pharmacy, Faculty of Health & Medical Sciences, University of Copenhagen, Copenhagen, Denmark.Department of Respiratory Medicine, Key Laboratory of Organ Regeneration & Transplantation of the Ministry of Education, the First Hospital of Jilin University, Changchun, PR China.Department of Respiratory Medicine, Key Laboratory of Organ Regeneration & Transplantation of the Ministry of Education, the First Hospital of Jilin University, Changchun, PR China.Department of Respiratory Medicine, Key Laboratory of Organ Regeneration & Transplantation of the Ministry of Education, the First Hospital of Jilin University, Changchun, PR China.Department of Respiratory Medicine, Key Laboratory of Organ Regeneration & Transplantation of the Ministry of Education, the First Hospital of Jilin University, Changchun, PR China.Department of Respiratory Medicine, Key Laboratory of Organ Regeneration & Transplantation of the Ministry of Education, the First Hospital of Jilin University, Changchun, PR China.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

33217886

Citation

Liu, Han, et al. "Epidemiological and Clinical Characteristics of 2019 Novel Coronavirus Disease (COVID-19) in Jilin, China: a Descriptive Study." Medicine, vol. 99, no. 47, 2020, pp. e23407.
Liu H, Gao J, Wang Y, et al. Epidemiological and clinical characteristics of 2019 novel coronavirus disease (COVID-19) in Jilin, China: A descriptive study. Medicine (Baltimore). 2020;99(47):e23407.
Liu, H., Gao, J., Wang, Y., Jie, J., Luo, J., Xu, Y., Sun, H., Song, L., Li, D., Peng, L., & Hua, S. (2020). Epidemiological and clinical characteristics of 2019 novel coronavirus disease (COVID-19) in Jilin, China: A descriptive study. Medicine, 99(47), e23407. https://doi.org/10.1097/MD.0000000000023407
Liu H, et al. Epidemiological and Clinical Characteristics of 2019 Novel Coronavirus Disease (COVID-19) in Jilin, China: a Descriptive Study. Medicine (Baltimore). 2020 Nov 20;99(47):e23407. PubMed PMID: 33217886.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Epidemiological and clinical characteristics of 2019 novel coronavirus disease (COVID-19) in Jilin, China: A descriptive study. AU - Liu,Han, AU - Gao,Jinying, AU - Wang,Yangyang, AU - Jie,Jing, AU - Luo,Jingjing, AU - Xu,You, AU - Sun,Hongying, AU - Song,Lei, AU - Li,Dan, AU - Peng,Liping, AU - Hua,Shucheng, PY - 2020/11/21/entrez PY - 2020/11/22/pubmed PY - 2020/12/1/medline SP - e23407 EP - e23407 JF - Medicine JO - Medicine (Baltimore) VL - 99 IS - 47 N2 - Coronavirus diseases 2019 (COVID-19) has become a global pandemic. To add to the scarce information on this disease, here, we investigated the epidemiological and clinical characteristics of 93 hospitalized patients with COVID-19 in Jilin, China from January 22 to March 15, 2020.We retrospectively investigated the demographic information, recent exposure history, clinical symptoms or signs, comorbidity, chest computed tomographic (CT) scan or X-ray results, laboratory test results, diagnostic classification, treatment, length of hospitalization, complications, and outcomes.Of the 93 patients, 54 were male and 39 female. More than half of these patients had a history of exposure to infected patients. The mean incubation period was 10.4 days in 87 patients, where the data was available. The 5 most common symptoms of illness onset were fever, cough, expectoration, fatigue, and dyspnea. One patient was asymptomatic. The imaging results were abnormal in majority of the patients. Almost one-third of the patients had lymphopenia. All patients received antiviral therapy, 84 patients were treated with antibiotics and 54 received different doses of the hormone for methylprednisolone. In addition, 72 patients used traditional Chinese medicine. Oxygen therapy, high nasal flow oxygen, non-invasive ventilator, invasive ventilator and extracorporeal membrane oxygenation (ECMO) were used symptomatically in different patients. Except 1 patient who died during treatment, all others were discharged.The average incubation time is prolonged in the present analysis, as compared to that in other reports. A few patients symptoms improved but CT exacerbated. Therefore, we suggest that close follow-up observation is still required after discharge. SN - 1536-5964 UR - https://www.unboundmedicine.com/medline/citation/33217886/Epidemiological_and_clinical_characteristics_of_2019_novel_coronavirus_disease__COVID_19__in_Jilin_China:_A_descriptive_study_ L2 - https://doi.org/10.1097/MD.0000000000023407 DB - PRIME DP - Unbound Medicine ER -