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The simultaneous inoculation of Mycobacterium leprae and M. intracellulare into nude mice: development of cutaneous leproma and accelleration of foot pad swelling.
Indian J Lepr. 1987 Oct-Dec; 59(4):426-34.IJ

Abstract

Organisms of the non-pathogenic Mycobacterium intracellulare serotype 19 Darden enhanced the pathogenicity of M. leprae when inoculated together into the foot pads of nude mice. This supporting effect could be demonstrated by an accelleration of foot pad swelling, beginning 4 months after inoculation and by the development of cutaneous leproma on dorsal and lateral body sites within 6 months after inoculation. These leproma increased in number and size during the 9 months they were under observation and demonstrated micromorphological characteristics similar to those of human leprosy.

Authors+Show Affiliations

Institute for Experimental Biology and Medicine, Borstel, FRG.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

3330554

Citation

Kazda, J, et al. "The Simultaneous Inoculation of Mycobacterium Leprae and M. Intracellulare Into Nude Mice: Development of Cutaneous Leproma and Accelleration of Foot Pad Swelling." Indian Journal of Leprosy, vol. 59, no. 4, 1987, pp. 426-34.
Kazda J, Fasske E, Kolk A, et al. The simultaneous inoculation of Mycobacterium leprae and M. intracellulare into nude mice: development of cutaneous leproma and accelleration of foot pad swelling. Indian J Lepr. 1987;59(4):426-34.
Kazda, J., Fasske, E., Kolk, A., Ganapati, R., & Schroder, K. H. (1987). The simultaneous inoculation of Mycobacterium leprae and M. intracellulare into nude mice: development of cutaneous leproma and accelleration of foot pad swelling. Indian Journal of Leprosy, 59(4), 426-34.
Kazda J, et al. The Simultaneous Inoculation of Mycobacterium Leprae and M. Intracellulare Into Nude Mice: Development of Cutaneous Leproma and Accelleration of Foot Pad Swelling. Indian J Lepr. 1987 Oct-Dec;59(4):426-34. PubMed PMID: 3330554.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The simultaneous inoculation of Mycobacterium leprae and M. intracellulare into nude mice: development of cutaneous leproma and accelleration of foot pad swelling. AU - Kazda,J, AU - Fasske,E, AU - Kolk,A, AU - Ganapati,R, AU - Schroder,K H, PY - 1987/10/1/pubmed PY - 1987/10/1/medline PY - 1987/10/1/entrez SP - 426 EP - 34 JF - Indian journal of leprosy JO - Indian J Lepr VL - 59 IS - 4 N2 - Organisms of the non-pathogenic Mycobacterium intracellulare serotype 19 Darden enhanced the pathogenicity of M. leprae when inoculated together into the foot pads of nude mice. This supporting effect could be demonstrated by an accelleration of foot pad swelling, beginning 4 months after inoculation and by the development of cutaneous leproma on dorsal and lateral body sites within 6 months after inoculation. These leproma increased in number and size during the 9 months they were under observation and demonstrated micromorphological characteristics similar to those of human leprosy. SN - 0254-9395 UR - https://www.unboundmedicine.com/medline/citation/3330554/The_simultaneous_inoculation_of_Mycobacterium_leprae_and_M__intracellulare_into_nude_mice:_development_of_cutaneous_leproma_and_accelleration_of_foot_pad_swelling_ L2 - https://medlineplus.gov/mycobacterialinfections.html DB - PRIME DP - Unbound Medicine ER -