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Cannabidiol - therapeutic and legal aspects.
Pharmazie. 2020 10 01; 75(10):463-469.P

Abstract

Cannabidiol (CBD) is an alkaloid present in Cannabis sativa, along with tetrahydrocannabinol (THC) and more than 100 other substances belonging to a group of compounds called cannabinoids. Whereas the legal status and medical use of Cannabis is a controversial issue in many countries, inconsistent legislation makes CBD status even more complicated. Some CBD products are legal in some countries, while banned in other countries, further compounding the confusion. In 2018, the Food and Drug Administration (FDA) approved the first CBD containing medical product, Epidiolex®, for the treatment of paediatric seizures. Currently, several clinical trials are in progress for the potential treatment of neurologic and behavioural disorders. CBD's current legal and regulatory status is a continuously evolving issue; the current review is presenting historical and present information regarding the use of CBD products worldwide.

Authors+Show Affiliations

Department of Pharmaceutical Technology and Cosmetology, Faculty of Pharmacy, "George Emil Palade" University of Medicine, Pharmacy, Science and Technology of Târgu Mureş, Târgu Mureş, Romania.Department of Pharmaceutical Chemistry, Faculty of Pharmacy, "George Emil Palade" University of Medicine, Pharmacy, Science and Technology of Târgu Mureş, Târgu Mureş, Romania;, Email: gabriel.hancu@umfst.ro.Department of Pharmaceutical Technology and Cosmetology, Faculty of Pharmacy, "George Emil Palade" University of Medicine, Pharmacy, Science and Technology of Târgu Mureş, Târgu Mureş, Romania.Department of Pharmaceutical Technology and Cosmetology, Faculty of Pharmacy, "George Emil Palade" University of Medicine, Pharmacy, Science and Technology of Târgu Mureş, Târgu Mureş, Romania.Department of Pharmaceutical Technology and Cosmetology, Faculty of Pharmacy, "George Emil Palade" University of Medicine, Pharmacy, Science and Technology of Târgu Mureş, Târgu Mureş, Romania.Department of Pharmaceutical Technology and Cosmetology, Faculty of Pharmacy, "George Emil Palade" University of Medicine, Pharmacy, Science and Technology of Târgu Mureş, Târgu Mureş, Romania.Department of Pharmaceutical Technology and Cosmetology, Faculty of Pharmacy, "George Emil Palade" University of Medicine, Pharmacy, Science and Technology of Târgu Mureş, Târgu Mureş, Romania.Department of Analytical Chemistry and Drug Analysis, Faculty of Pharmacy, "George Emil Palade" University of Medicine, Pharmacy, Science and Technology of Târgu Mureş, Târgu Mureş, Romania.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

33305718

Citation

Vlad, R A., et al. "Cannabidiol - Therapeutic and Legal Aspects." Die Pharmazie, vol. 75, no. 10, 2020, pp. 463-469.
Vlad RA, Hancu G, Ciurba A, et al. Cannabidiol - therapeutic and legal aspects. Pharmazie. 2020;75(10):463-469.
Vlad, R. A., Hancu, G., Ciurba, A., Antonoaea, P., Rédai, E. M., Todoran, N., Silasi, O., & Muntean, D. L. (2020). Cannabidiol - therapeutic and legal aspects. Die Pharmazie, 75(10), 463-469. https://doi.org/10.1691/ph.2020.0076
Vlad RA, et al. Cannabidiol - Therapeutic and Legal Aspects. Pharmazie. 2020 10 1;75(10):463-469. PubMed PMID: 33305718.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cannabidiol - therapeutic and legal aspects. AU - Vlad,R A, AU - Hancu,G, AU - Ciurba,A, AU - Antonoaea,P, AU - Rédai,E M, AU - Todoran,N, AU - Silasi,O, AU - Muntean,D L, PY - 2020/12/11/entrez PY - 2020/12/12/pubmed PY - 2021/9/15/medline SP - 463 EP - 469 JF - Die Pharmazie JO - Pharmazie VL - 75 IS - 10 N2 - Cannabidiol (CBD) is an alkaloid present in Cannabis sativa, along with tetrahydrocannabinol (THC) and more than 100 other substances belonging to a group of compounds called cannabinoids. Whereas the legal status and medical use of Cannabis is a controversial issue in many countries, inconsistent legislation makes CBD status even more complicated. Some CBD products are legal in some countries, while banned in other countries, further compounding the confusion. In 2018, the Food and Drug Administration (FDA) approved the first CBD containing medical product, Epidiolex®, for the treatment of paediatric seizures. Currently, several clinical trials are in progress for the potential treatment of neurologic and behavioural disorders. CBD's current legal and regulatory status is a continuously evolving issue; the current review is presenting historical and present information regarding the use of CBD products worldwide. SN - 0031-7144 UR - https://www.unboundmedicine.com/medline/citation/33305718/Cannabidiol___therapeutic_and_legal_aspects_ L2 - https://www.ingentaconnect.com/openurl?genre=article&issn=0031-7144&volume=75&issue=10&spage=463&aulast=Vlad DB - PRIME DP - Unbound Medicine ER -