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Ethical allocation of future COVID-19 vaccines.
J Med Ethics. 2020 Dec 17 [Online ahead of print]JM

Abstract

The COVID-19 pandemic will likely recede only through development and distribution of an effective vaccine. Although there are many unknowns surrounding COVID-19 vaccine development, vaccine demand will likely outstrip early supply, making prospective planning for vaccine allocation critical for ensuring the ethical distribution of COVID-19 vaccines. Here, we propose three central goals for COVID-19 vaccination campaigns: to reduce morbidity and mortality, to minimise additional economic and societal burdens related to the pandemic and to narrow unjust health inequalities. We evaluate five prioritisation approaches, assess their likely impact on advancing the three goals of vaccine allocation and identify open scientific questions that may alter their outcomes. We argue that no single prioritisation approach will advance all three goals. Instead, we propose a multipronged approach that considers the risk of serious COVID-19 illness, instrumental value and the risk of transmission, and is guided by future research on COVID-19-specific clinical and vaccine characteristics. While we focus this assessment on the USA, our analysis can inform allocation in other contexts.

Authors+Show Affiliations

School of Medicine, Baylor College of Medicine, Houston, Texas, USA rohit.gupta@bcm.edu.Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, Texas, USA.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

33335070

Citation

Gupta, Rohit, and Stephanie R. Morain. "Ethical Allocation of Future COVID-19 Vaccines." Journal of Medical Ethics, 2020.
Gupta R, Morain SR. Ethical allocation of future COVID-19 vaccines. J Med Ethics. 2020.
Gupta, R., & Morain, S. R. (2020). Ethical allocation of future COVID-19 vaccines. Journal of Medical Ethics. https://doi.org/10.1136/medethics-2020-106850
Gupta R, Morain SR. Ethical Allocation of Future COVID-19 Vaccines. J Med Ethics. 2020 Dec 17; PubMed PMID: 33335070.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ethical allocation of future COVID-19 vaccines. AU - Gupta,Rohit, AU - Morain,Stephanie R, Y1 - 2020/12/17/ PY - 2020/08/26/received PY - 2020/12/07/revised PY - 2020/12/10/accepted PY - 2020/12/19/pubmed PY - 2020/12/19/medline PY - 2020/12/18/entrez KW - allocation of health care resources KW - clinical ethics KW - health care for specific diseases/groups KW - public health ethics JF - Journal of medical ethics JO - J Med Ethics N2 - The COVID-19 pandemic will likely recede only through development and distribution of an effective vaccine. Although there are many unknowns surrounding COVID-19 vaccine development, vaccine demand will likely outstrip early supply, making prospective planning for vaccine allocation critical for ensuring the ethical distribution of COVID-19 vaccines. Here, we propose three central goals for COVID-19 vaccination campaigns: to reduce morbidity and mortality, to minimise additional economic and societal burdens related to the pandemic and to narrow unjust health inequalities. We evaluate five prioritisation approaches, assess their likely impact on advancing the three goals of vaccine allocation and identify open scientific questions that may alter their outcomes. We argue that no single prioritisation approach will advance all three goals. Instead, we propose a multipronged approach that considers the risk of serious COVID-19 illness, instrumental value and the risk of transmission, and is guided by future research on COVID-19-specific clinical and vaccine characteristics. While we focus this assessment on the USA, our analysis can inform allocation in other contexts. SN - 1473-4257 UR - https://www.unboundmedicine.com/medline/citation/33335070/Ethical_allocation_of_future_COVID_19_vaccines_ L2 - https://jme.bmj.com/lookup/pmidlookup?view=long&pmid=33335070 DB - PRIME DP - Unbound Medicine ER -
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