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Hepatic hemodynamics after chronic obstruction of the biliary tract in the dog.
Surg Gynecol Obstet. 1988 Feb; 166(2):125-30.SG

Abstract

Hepatic blood flow was measured in 12 dogs before and two weeks after obstruction of the bile duct (BD) or sham operation, using the electromagnetic flowmeter technique. Eight dogs with obstructed BD revealed an 41 per cent decrease in total hepatic blood flow caused by an approximately equal percentage decrease in both hepatic arterial (HA) and portal venous (PV) flow, a decrease in arterial blood pressure, an increase in PV vascular resistance and little change in hepatic oxygen consumption. Four sham operated dogs showed minimal hemodynamic response. A dual mechanism for the hepatic hemodynamic consequences of chronic biliary obstruction is suggested: Decreased HA blood flow associated with diminished blood pressure and reduced PV blood flow resulting from raised intrahepatic PV vascular resistance.

Authors+Show Affiliations

Department of Surgery, Royal Postgraduate Medical School, Hammersmith Hospital, London, United Kingdom.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

3336825

Citation

Mathie, R T., et al. "Hepatic Hemodynamics After Chronic Obstruction of the Biliary Tract in the Dog." Surgery, Gynecology & Obstetrics, vol. 166, no. 2, 1988, pp. 125-30.
Mathie RT, Nagorney DM, Lewis MH, et al. Hepatic hemodynamics after chronic obstruction of the biliary tract in the dog. Surg Gynecol Obstet. 1988;166(2):125-30.
Mathie, R. T., Nagorney, D. M., Lewis, M. H., & Blumgart, L. H. (1988). Hepatic hemodynamics after chronic obstruction of the biliary tract in the dog. Surgery, Gynecology & Obstetrics, 166(2), 125-30.
Mathie RT, et al. Hepatic Hemodynamics After Chronic Obstruction of the Biliary Tract in the Dog. Surg Gynecol Obstet. 1988;166(2):125-30. PubMed PMID: 3336825.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hepatic hemodynamics after chronic obstruction of the biliary tract in the dog. AU - Mathie,R T, AU - Nagorney,D M, AU - Lewis,M H, AU - Blumgart,L H, PY - 1988/2/1/pubmed PY - 1988/2/1/medline PY - 1988/2/1/entrez SP - 125 EP - 30 JF - Surgery, gynecology & obstetrics JO - Surg Gynecol Obstet VL - 166 IS - 2 N2 - Hepatic blood flow was measured in 12 dogs before and two weeks after obstruction of the bile duct (BD) or sham operation, using the electromagnetic flowmeter technique. Eight dogs with obstructed BD revealed an 41 per cent decrease in total hepatic blood flow caused by an approximately equal percentage decrease in both hepatic arterial (HA) and portal venous (PV) flow, a decrease in arterial blood pressure, an increase in PV vascular resistance and little change in hepatic oxygen consumption. Four sham operated dogs showed minimal hemodynamic response. A dual mechanism for the hepatic hemodynamic consequences of chronic biliary obstruction is suggested: Decreased HA blood flow associated with diminished blood pressure and reduced PV blood flow resulting from raised intrahepatic PV vascular resistance. SN - 0039-6087 UR - https://www.unboundmedicine.com/medline/citation/3336825/Hepatic_hemodynamics_after_chronic_obstruction_of_the_biliary_tract_in_the_dog_ DB - PRIME DP - Unbound Medicine ER -