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Commentary: Identifying individualized predictions of response in ADHD pharmacotherapy - a commentary on Rodrigues et al. (2020).
J Child Psychol Psychiatry. 2021 06; 62(6):701-703.JC

Abstract

In this issue, Rodrigues et al. (2020) present a systematic review with meta-analyses that reports the efficacy of five treatments for children with attention-deficit hyperactivity disorder symptoms in the context of autism spectrum disorder - (a) methylphenidate; (b) atomoxetine; (c) guanfacine; (d) aripiprazole; and (e) risperidone. In this commentary, we highlight the contrast between the scarce evidence base of treatment for ADHD in the context of autism and other subpopulations, such as tic disorders and intellectual disability, and the extensive evidence base of treatment for ADHD in general. The commentary weighs about the conundrum clinicians face of whether to rely on the limited evidence base of treatment for ADHD in subpopulation, or to derive conclusions from the larger body of evidence of treatment for ADHD in general. The commentary also discusses potential avenues for future research to address this clinical problem.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Farhat LC
Departament of Psychiatry, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, Brazil.
Bloch MH
Yale Child Study Center, Yale University School of Medicine, New Haven, CT, USA. Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.

MeSH

Atomoxetine HydrochlorideAttention Deficit Disorder with HyperactivityAutism Spectrum DisorderChildGuanfacineHumansMethylphenidate

Pub Type(s)

Journal Article
Comment

Language

eng

PubMed ID

33368287

Citation

Farhat, Luis C., and Michael H. Bloch. "Commentary: Identifying Individualized Predictions of Response in ADHD Pharmacotherapy - a Commentary On Rodrigues Et Al. (2020)." Journal of Child Psychology and Psychiatry, and Allied Disciplines, vol. 62, no. 6, 2021, pp. 701-703.
Farhat LC, Bloch MH. Commentary: Identifying individualized predictions of response in ADHD pharmacotherapy - a commentary on Rodrigues et al. (2020). J Child Psychol Psychiatry. 2021;62(6):701-703.
Farhat, L. C., & Bloch, M. H. (2021). Commentary: Identifying individualized predictions of response in ADHD pharmacotherapy - a commentary on Rodrigues et al. (2020). Journal of Child Psychology and Psychiatry, and Allied Disciplines, 62(6), 701-703. https://doi.org/10.1111/jcpp.13374
Farhat LC, Bloch MH. Commentary: Identifying Individualized Predictions of Response in ADHD Pharmacotherapy - a Commentary On Rodrigues Et Al. (2020). J Child Psychol Psychiatry. 2021;62(6):701-703. PubMed PMID: 33368287.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Commentary: Identifying individualized predictions of response in ADHD pharmacotherapy - a commentary on Rodrigues et al. (2020). AU - Farhat,Luis C, AU - Bloch,Michael H, Y1 - 2020/12/24/ PY - 2020/11/05/received PY - 2020/11/30/accepted PY - 2020/12/29/pubmed PY - 2021/8/18/medline PY - 2020/12/28/entrez SP - 701 EP - 703 JF - Journal of child psychology and psychiatry, and allied disciplines JO - J Child Psychol Psychiatry VL - 62 IS - 6 N2 - In this issue, Rodrigues et al. (2020) present a systematic review with meta-analyses that reports the efficacy of five treatments for children with attention-deficit hyperactivity disorder symptoms in the context of autism spectrum disorder - (a) methylphenidate; (b) atomoxetine; (c) guanfacine; (d) aripiprazole; and (e) risperidone. In this commentary, we highlight the contrast between the scarce evidence base of treatment for ADHD in the context of autism and other subpopulations, such as tic disorders and intellectual disability, and the extensive evidence base of treatment for ADHD in general. The commentary weighs about the conundrum clinicians face of whether to rely on the limited evidence base of treatment for ADHD in subpopulation, or to derive conclusions from the larger body of evidence of treatment for ADHD in general. The commentary also discusses potential avenues for future research to address this clinical problem. SN - 1469-7610 UR - https://www.unboundmedicine.com/medline/citation/33368287/Commentary:_Identifying_individualized_predictions_of_response_in_ADHD_pharmacotherapy_-_a_commentary_on_Rodrigues_et_al._(2020). DB - PRIME DP - Unbound Medicine ER -