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Iron absorption in humans: bovine serum albumin compared with beef muscle and egg white.
Am J Clin Nutr. 1988 Jan; 47(1):102-7.AJ

Abstract

We studied the influence of bovine serum albumin and beef meat on nonheme iron absorption in humans and on dialyzable iron in vitro. The addition of serum albumin to a maize gruel had no significant effect on nonheme Fe absorption whereas the addition of beef meat caused a threefold increase. When added to a bread meal, serum albumin caused a modest 60% increase in nonheme Fe absorption and beef meat had no effect. When added to a protein-free meal, serum albumin reduced Fe absorption by 47% compared with a 72% reduction on addition of egg white. The bioavailability of nonheme Fe from meals containing serum albumin was consistently overestimated by the in vitro technique. We conclude that the facilitation of nonheme Fe absorption by meat is not a general property of all animal protein but is better explained by the action of one or more specific animal tissues.

Authors+Show Affiliations

Department of Medicine, University of Kansas Medical Center, Kansas City 66103.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Controlled Clinical Trial
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

3337027

Citation

Hurrell, R F., et al. "Iron Absorption in Humans: Bovine Serum Albumin Compared With Beef Muscle and Egg White." The American Journal of Clinical Nutrition, vol. 47, no. 1, 1988, pp. 102-7.
Hurrell RF, Lynch SR, Trinidad TP, et al. Iron absorption in humans: bovine serum albumin compared with beef muscle and egg white. Am J Clin Nutr. 1988;47(1):102-7.
Hurrell, R. F., Lynch, S. R., Trinidad, T. P., Dassenko, S. A., & Cook, J. D. (1988). Iron absorption in humans: bovine serum albumin compared with beef muscle and egg white. The American Journal of Clinical Nutrition, 47(1), 102-7.
Hurrell RF, et al. Iron Absorption in Humans: Bovine Serum Albumin Compared With Beef Muscle and Egg White. Am J Clin Nutr. 1988;47(1):102-7. PubMed PMID: 3337027.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Iron absorption in humans: bovine serum albumin compared with beef muscle and egg white. AU - Hurrell,R F, AU - Lynch,S R, AU - Trinidad,T P, AU - Dassenko,S A, AU - Cook,J D, PY - 1988/1/1/pubmed PY - 1988/1/1/medline PY - 1988/1/1/entrez SP - 102 EP - 7 JF - The American journal of clinical nutrition JO - Am J Clin Nutr VL - 47 IS - 1 N2 - We studied the influence of bovine serum albumin and beef meat on nonheme iron absorption in humans and on dialyzable iron in vitro. The addition of serum albumin to a maize gruel had no significant effect on nonheme Fe absorption whereas the addition of beef meat caused a threefold increase. When added to a bread meal, serum albumin caused a modest 60% increase in nonheme Fe absorption and beef meat had no effect. When added to a protein-free meal, serum albumin reduced Fe absorption by 47% compared with a 72% reduction on addition of egg white. The bioavailability of nonheme Fe from meals containing serum albumin was consistently overestimated by the in vitro technique. We conclude that the facilitation of nonheme Fe absorption by meat is not a general property of all animal protein but is better explained by the action of one or more specific animal tissues. SN - 0002-9165 UR - https://www.unboundmedicine.com/medline/citation/3337027/Iron_absorption_in_humans:_bovine_serum_albumin_compared_with_beef_muscle_and_egg_white_ DB - PRIME DP - Unbound Medicine ER -