TY - JOUR T1 - Recent Developments on Therapeutic and Diagnostic Approaches for COVID-19. AU - Majumder,Joydeb, AU - Minko,Tamara, Y1 - 2021/01/05/ PY - 2020/09/04/received PY - 2020/11/03/accepted PY - 2021/1/5/entrez PY - 2021/1/6/pubmed PY - 2021/1/14/medline KW - ARDS KW - anti-SARS-CoV-2 antibody KW - antiviral drugs KW - antiviral vaccines KW - convalescent plasma therapy KW - immunotherapy KW - nanotherapeutics SP - 14 EP - 14 JF - The AAPS journal JO - AAPS J VL - 23 IS - 1 N2 - The ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has made a serious public health threat worldwide with millions of people at risk in a growing number of countries. Though there are no clinically approved antiviral drugs and vaccines for COVID-19, attempts are ongoing for clinical trials of several known antiviral drugs, their combination, as well as development of vaccines in patients with confirmed COVID-19. This review focuses on the latest approaches to diagnostics and therapy of COVID-19. We have summarized recent progress on the conventional therapeutics such as antiviral drugs, vaccines, anti-SARS-CoV-2 antibody treatments, and convalescent plasma therapy which are currently under extensive research and clinical trials for the treatment of COVID-19. The developments of nanoparticle-based therapeutic and diagnostic approaches have been also discussed for COVID-19. We have assessed recent literature data on this topic and made a summary of current development and future perspectives. SN - 1550-7416 UR - https://www.unboundmedicine.com/medline/citation/33400058/Recent_Developments_on_Therapeutic_and_Diagnostic_Approaches_for_COVID_19_ DB - PRIME DP - Unbound Medicine ER -