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Association between dry eye and traditional Chinese medicine body constitutions: A Taiwanese adults study.
Medicine (Baltimore). 2021 Jan 15; 100(2):e24265.M

Abstract

ABSTRACT

In the theory of traditional Chinese medicine (TCM), except for the balanced constitution, other constitutions are unbalanced and may lead to susceptibility to certain diseases. This study made the first efforts to explore the relationship between TCM constitutions and the dry eye condition.This cross-sectional study collected information from 2760 subjects aged 30 to 70 years who had participated in a questionnaire survey conducted by Taiwan Biobank (TWB) in 2012 to 2017. The questionnaire included questions on basic demographic characteristics, chronic diseases, depression, blood lipid levels, lifestyles, and drug allergies, as well as a TCM constitution scale developed by a research team of TCM constitution and syndrome at China Medical University College of Chinese Medicine.Unadjusted and stratified multiple logistic regression analyses were performed to explore the relationships between TCM constitutions and dry eye. The analysis revealed that subjects falling into the constitution category of Yang deficiency, Yin deficiency, or Phlegm stasis were more likely to develop dry eyes (crude odds ratio [OR] = 1.741, 95% confidence interval [CI] = 1.361-2.227; crude OR = 2.4821, 95% CI = 1.968-3.131; and crude OR = 2.082, 95% CI = 1.597-2.714, respectively). After adjusting for important risk factors (demographic characteristics, chronic diseases, blood lipid levels, lifestyles, depression, and drug allergies), subjects with an unbalanced constitution were 1.6 to 2.5 times more likely to develop dry eye than those with a balanced constitution.These results confirm a high correlation of TCM constitution with dry eye. Considering that the current treatment outcome is not fully satisfactory to the patients with dry eyes, integration of TCM and Western medicine may be an alternative treatment option. Individualized treatments and lifestyle recommended should be provided to patients with different TCM constitutions to alleviate dry eye symptoms.

Authors+Show Affiliations

Department of Ophthalmology, Kaohsiung Veterans General Hospital. College of Medicine, Kaohsiung Medical University.Department of Family Medicine, Kaohsiung Veterans General Hospital. Department of Nursing, Shu-Zen Junior College of Medicine and Management.Research Center of Medical Informatics, Kaohsiung Veterans General Hospital. Department of Health-Business Administration, Fooyin University, Kaohsiung, Taiwan (ROC).

Pub Type(s)

Evaluation Study
Journal Article

Language

eng

PubMed ID

33466213

Citation

Chen, Shih-Lin, et al. "Association Between Dry Eye and Traditional Chinese Medicine Body Constitutions: a Taiwanese Adults Study." Medicine, vol. 100, no. 2, 2021, pp. e24265.
Chen SL, Hsueh KC, Tang PL. Association between dry eye and traditional Chinese medicine body constitutions: A Taiwanese adults study. Medicine (Baltimore). 2021;100(2):e24265.
Chen, S. L., Hsueh, K. C., & Tang, P. L. (2021). Association between dry eye and traditional Chinese medicine body constitutions: A Taiwanese adults study. Medicine, 100(2), e24265. https://doi.org/10.1097/MD.0000000000024265
Chen SL, Hsueh KC, Tang PL. Association Between Dry Eye and Traditional Chinese Medicine Body Constitutions: a Taiwanese Adults Study. Medicine (Baltimore). 2021 Jan 15;100(2):e24265. PubMed PMID: 33466213.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Association between dry eye and traditional Chinese medicine body constitutions: A Taiwanese adults study. AU - Chen,Shih-Lin, AU - Hsueh,Kuang-Chieh, AU - Tang,Pei-Ling, PY - 2020/06/11/received PY - 2020/12/12/accepted PY - 2021/1/20/entrez PY - 2021/1/21/pubmed PY - 2021/1/26/medline SP - e24265 EP - e24265 JF - Medicine JO - Medicine (Baltimore) VL - 100 IS - 2 N2 - ABSTRACT: In the theory of traditional Chinese medicine (TCM), except for the balanced constitution, other constitutions are unbalanced and may lead to susceptibility to certain diseases. This study made the first efforts to explore the relationship between TCM constitutions and the dry eye condition.This cross-sectional study collected information from 2760 subjects aged 30 to 70 years who had participated in a questionnaire survey conducted by Taiwan Biobank (TWB) in 2012 to 2017. The questionnaire included questions on basic demographic characteristics, chronic diseases, depression, blood lipid levels, lifestyles, and drug allergies, as well as a TCM constitution scale developed by a research team of TCM constitution and syndrome at China Medical University College of Chinese Medicine.Unadjusted and stratified multiple logistic regression analyses were performed to explore the relationships between TCM constitutions and dry eye. The analysis revealed that subjects falling into the constitution category of Yang deficiency, Yin deficiency, or Phlegm stasis were more likely to develop dry eyes (crude odds ratio [OR] = 1.741, 95% confidence interval [CI] = 1.361-2.227; crude OR = 2.4821, 95% CI = 1.968-3.131; and crude OR = 2.082, 95% CI = 1.597-2.714, respectively). After adjusting for important risk factors (demographic characteristics, chronic diseases, blood lipid levels, lifestyles, depression, and drug allergies), subjects with an unbalanced constitution were 1.6 to 2.5 times more likely to develop dry eye than those with a balanced constitution.These results confirm a high correlation of TCM constitution with dry eye. Considering that the current treatment outcome is not fully satisfactory to the patients with dry eyes, integration of TCM and Western medicine may be an alternative treatment option. Individualized treatments and lifestyle recommended should be provided to patients with different TCM constitutions to alleviate dry eye symptoms. SN - 1536-5964 UR - https://www.unboundmedicine.com/medline/citation/33466213/Association_between_dry_eye_and_traditional_Chinese_medicine_body_constitutions:_A_Taiwanese_adults_study_ L2 - https://doi.org/10.1097/MD.0000000000024265 DB - PRIME DP - Unbound Medicine ER -