Tags

Type your tag names separated by a space and hit enter

Armochaetoglasins J and K: new cytochalasans from Chaetomium globosum.
Nat Prod Res. 2022 Jul; 36(14):3603-3609.NP

Abstract

Two novel cytochalasans, armochaetoglasin J (1) and armochaetoglasin K (2), along with 14 known analogues (3-16) were isolated from Chaetomium globosum. Their structures were elucidated by HRESIMS, NMR spectroscopy, single-crystal X-ray crystallography, and ECD spectra. Armochaetoglasins J and K were found to be inactive against the HepG2, HT-29, K562, HL-60, and A549 cancer cell lines.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Cheng L
Hubei Key Laboratory of Wudang Local Chinese Medicine Research, Hubei Engineering Technology Center for Comprehensive Utilization of Medicinal Plants, College of Pharmacy, Hubei University of Medicine, Shiyan, People's Republic of China.
Zheng X
Hubei Key Laboratory of Wudang Local Chinese Medicine Research, Hubei Engineering Technology Center for Comprehensive Utilization of Medicinal Plants, College of Pharmacy, Hubei University of Medicine, Shiyan, People's Republic of China.
Li Q
Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.
Wei MS
Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.
Chen CM
Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.
Zhu HC
Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.
Zeng CL
Hubei Engineering Research Center for Protection and Utilization of Special Biological Resources in the Hanjiang River Basin, Jianghan University, Wuhan, People's Republic of China.
Hao XC
Hubei Key Laboratory of Wudang Local Chinese Medicine Research, Hubei Engineering Technology Center for Comprehensive Utilization of Medicinal Plants, College of Pharmacy, Hubei University of Medicine, Shiyan, People's Republic of China.
Zhang YH
Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.

MeSH

ChaetomiumCrystallography, X-RayCytochalasinsHL-60 CellsHumans

Pub Type(s)

Journal Article

Language

eng

PubMed ID

33487054

Citation

Cheng, Li, et al. "Armochaetoglasins J and K: New Cytochalasans From Chaetomium Globosum." Natural Product Research, vol. 36, no. 14, 2022, pp. 3603-3609.
Cheng L, Zheng X, Li Q, et al. Armochaetoglasins J and K: new cytochalasans from Chaetomium globosum. Nat Prod Res. 2022;36(14):3603-3609.
Cheng, L., Zheng, X., Li, Q., Wei, M. S., Chen, C. M., Zhu, H. C., Zeng, C. L., Hao, X. C., & Zhang, Y. H. (2022). Armochaetoglasins J and K: new cytochalasans from Chaetomium globosum. Natural Product Research, 36(14), 3603-3609. https://doi.org/10.1080/14786419.2021.1872568
Cheng L, et al. Armochaetoglasins J and K: New Cytochalasans From Chaetomium Globosum. Nat Prod Res. 2022;36(14):3603-3609. PubMed PMID: 33487054.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Armochaetoglasins J and K: new cytochalasans from Chaetomium globosum. AU - Cheng,Li, AU - Zheng,Xi, AU - Li,Qin, AU - Wei,Meng-Sha, AU - Chen,Chun-Mei, AU - Zhu,Hu-Cheng, AU - Zeng,Chang-Li, AU - Hao,Xin-Cai, AU - Zhang,Yong-Hui, Y1 - 2021/01/25/ PY - 2021/1/26/pubmed PY - 2022/7/19/medline PY - 2021/1/25/entrez KW - Chaetomium globosum KW - cytochalasan KW - secondary metabolites SP - 3603 EP - 3609 JF - Natural product research JO - Nat Prod Res VL - 36 IS - 14 N2 - Two novel cytochalasans, armochaetoglasin J (1) and armochaetoglasin K (2), along with 14 known analogues (3-16) were isolated from Chaetomium globosum. Their structures were elucidated by HRESIMS, NMR spectroscopy, single-crystal X-ray crystallography, and ECD spectra. Armochaetoglasins J and K were found to be inactive against the HepG2, HT-29, K562, HL-60, and A549 cancer cell lines. SN - 1478-6427 UR - https://www.unboundmedicine.com/medline/citation/33487054/Armochaetoglasins_J_and_K:_new_cytochalasans_from_Chaetomium_globosum_ DB - PRIME DP - Unbound Medicine ER -