Tags

Type your tag names separated by a space and hit enter

Retinal applications of swept source optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA).
Prog Retin Eye Res. 2021 Sep; 84:100951.PR

Abstract

The advent of optical coherence tomography (OCT) revolutionized both clinical assessment and research of vitreoretinal conditions. Since then, extraordinary advances have been made in this imaging technology, including the relatively recent development of swept-source OCT (SS-OCT). SS-OCT enables a fast scan rate and utilizes a tunable swept laser, thus enabling the incorporation of longer wavelengths than conventional spectral-domain devices. These features enable imaging of larger areas with reduced motion artifact, and a better visualization of the choroidal vasculature, respectively. Building on the principles of OCT, swept-source OCT has also been applied to OCT angiography (SS-OCTA), thus enabling a non-invasive in depth-resolved imaging of the retinal and choroidal microvasculature. Despite their advantages, the widespread use of SS-OCT and SS-OCTA remains relatively limited. In this review, we summarize the technical details, advantages and limitations of SS-OCT and SS-OCTA, with a particular emphasis on their relevance for the study of retinal conditions. Additionally, we comprehensively review relevant studies performed to date to the study of retinal health and disease, and highlight current gaps in knowledge and opportunities to take advantage of swept source technology to improve our current understanding of many medical and surgical chorioretinal conditions. We anticipate that SS-OCT and SS-OCTA will continue to evolve rapidly, contributing to a paradigm shift to more widespread adoption of new imaging technology to clinical practice.

Authors+Show Affiliations

Retina Service, Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA; Harvard Retinal Imaging Lab, Boston, MA, USA.Retina Service, Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA; Harvard Retinal Imaging Lab, Boston, MA, USA.Retina Service, Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA; Harvard Retinal Imaging Lab, Boston, MA, USA; Guangdong Eye Institute, Department of Ophthalmology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.Retina Service, Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA; Harvard Retinal Imaging Lab, Boston, MA, USA.Retina Service, Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA; Harvard Retinal Imaging Lab, Boston, MA, USA.Eye Clinic, Department of Biomedical and Clinical Science "Luigi Sacco", University of Milan, Italy.Retina Service, Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.Retina Service, Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.Retina Service, Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA; Harvard Retinal Imaging Lab, Boston, MA, USA. Electronic address: john_miller@meei.harvard.edu.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

33516833

Citation

Laíns, Inês, et al. "Retinal Applications of Swept Source Optical Coherence Tomography (OCT) and Optical Coherence Tomography Angiography (OCTA)." Progress in Retinal and Eye Research, vol. 84, 2021, p. 100951.
Laíns I, Wang JC, Cui Y, et al. Retinal applications of swept source optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA). Prog Retin Eye Res. 2021;84:100951.
Laíns, I., Wang, J. C., Cui, Y., Katz, R., Vingopoulos, F., Staurenghi, G., Vavvas, D. G., Miller, J. W., & Miller, J. B. (2021). Retinal applications of swept source optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA). Progress in Retinal and Eye Research, 84, 100951. https://doi.org/10.1016/j.preteyeres.2021.100951
Laíns I, et al. Retinal Applications of Swept Source Optical Coherence Tomography (OCT) and Optical Coherence Tomography Angiography (OCTA). Prog Retin Eye Res. 2021;84:100951. PubMed PMID: 33516833.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Retinal applications of swept source optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA). AU - Laíns,Inês, AU - Wang,Jay C, AU - Cui,Ying, AU - Katz,Raviv, AU - Vingopoulos,Filippos, AU - Staurenghi,Giovanni, AU - Vavvas,Demetrios G, AU - Miller,Joan W, AU - Miller,John B, Y1 - 2021/01/28/ PY - 2020/07/28/received PY - 2021/01/17/revised PY - 2021/01/20/accepted PY - 2021/2/1/pubmed PY - 2021/2/1/medline PY - 2021/1/31/entrez KW - Choroid KW - Imaging KW - Optical coherence tomography KW - Optical coherence tomography angiography KW - Retina KW - Swept source KW - Vitreous SP - 100951 EP - 100951 JF - Progress in retinal and eye research JO - Prog Retin Eye Res VL - 84 N2 - The advent of optical coherence tomography (OCT) revolutionized both clinical assessment and research of vitreoretinal conditions. Since then, extraordinary advances have been made in this imaging technology, including the relatively recent development of swept-source OCT (SS-OCT). SS-OCT enables a fast scan rate and utilizes a tunable swept laser, thus enabling the incorporation of longer wavelengths than conventional spectral-domain devices. These features enable imaging of larger areas with reduced motion artifact, and a better visualization of the choroidal vasculature, respectively. Building on the principles of OCT, swept-source OCT has also been applied to OCT angiography (SS-OCTA), thus enabling a non-invasive in depth-resolved imaging of the retinal and choroidal microvasculature. Despite their advantages, the widespread use of SS-OCT and SS-OCTA remains relatively limited. In this review, we summarize the technical details, advantages and limitations of SS-OCT and SS-OCTA, with a particular emphasis on their relevance for the study of retinal conditions. Additionally, we comprehensively review relevant studies performed to date to the study of retinal health and disease, and highlight current gaps in knowledge and opportunities to take advantage of swept source technology to improve our current understanding of many medical and surgical chorioretinal conditions. We anticipate that SS-OCT and SS-OCTA will continue to evolve rapidly, contributing to a paradigm shift to more widespread adoption of new imaging technology to clinical practice. SN - 1873-1635 UR - https://www.unboundmedicine.com/medline/citation/33516833/Retinal_applications_of_swept_source_optical_coherence_tomography_(OCT)_and_optical_coherence_tomography_angiography_(OCTA). L2 - https://scite.ai/reports/33516833 DB - PRIME DP - Unbound Medicine ER -
Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.