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Impact of progesterone on skin and hair in menopause - a comprehensive review.
Climacteric. 2021 06; 24(3):229-235.C

Abstract

In clinical practice, micronized progesterone (MP) is frequently recommended to treat signs and symptoms of skin and hair aging in menopausal women. The aim of this comprehensive review was to evaluate whether topically or systemically applied MP may effectively prevent or slow down signs of skin and hair aging. Three out of six identified studies reported an impact of MP on skin aging markers in menopausal women. Of these, two studies reported a benefit: one for topically applied MP, another for systemically applied combined menopausal hormone therapy (MHT) comprising MP as progestogen for endometrial protection. Tolerability and safety of MP were good. However, there was no study investigating the impact of MP on menopausal scalp hair. In conclusion, delay of skin aging comprises lifestyle adjustment, antioxidants, and several esthetic procedures. In menopausal women, MHT displays beneficial effects on skin aging. There is poor quality but promising scientific evidence for MP displaying anti-aging skin effects in menopausal women. However, good quality studies are needed.

Authors+Show Affiliations

Department of Obstetrics and Gynecology, University Clinic Inselspital, Bern, Switzerland.Department of Dermatology, University Clinic Inselspital, Bern, Switzerland.Department of Obstetrics and Gynecology, University Clinic Inselspital, Bern, Switzerland.Department of Obstetrics and Gynecology, University Clinic Inselspital, Bern, Switzerland.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

33527841

Citation

Gasser, S, et al. "Impact of Progesterone On Skin and Hair in Menopause - a Comprehensive Review." Climacteric : the Journal of the International Menopause Society, vol. 24, no. 3, 2021, pp. 229-235.
Gasser S, Heidemeyer K, von Wolff M, et al. Impact of progesterone on skin and hair in menopause - a comprehensive review. Climacteric. 2021;24(3):229-235.
Gasser, S., Heidemeyer, K., von Wolff, M., & Stute, P. (2021). Impact of progesterone on skin and hair in menopause - a comprehensive review. Climacteric : the Journal of the International Menopause Society, 24(3), 229-235. https://doi.org/10.1080/13697137.2020.1838476
Gasser S, et al. Impact of Progesterone On Skin and Hair in Menopause - a Comprehensive Review. Climacteric. 2021;24(3):229-235. PubMed PMID: 33527841.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Impact of progesterone on skin and hair in menopause - a comprehensive review. AU - Gasser,S, AU - Heidemeyer,K, AU - von Wolff,M, AU - Stute,P, Y1 - 2021/02/02/ PY - 2021/2/3/pubmed PY - 2021/11/4/medline PY - 2021/2/2/entrez KW - Progesterone KW - anti-aging KW - hair KW - hormone therapy KW - menopause KW - skin KW - sleep SP - 229 EP - 235 JF - Climacteric : the journal of the International Menopause Society JO - Climacteric VL - 24 IS - 3 N2 - In clinical practice, micronized progesterone (MP) is frequently recommended to treat signs and symptoms of skin and hair aging in menopausal women. The aim of this comprehensive review was to evaluate whether topically or systemically applied MP may effectively prevent or slow down signs of skin and hair aging. Three out of six identified studies reported an impact of MP on skin aging markers in menopausal women. Of these, two studies reported a benefit: one for topically applied MP, another for systemically applied combined menopausal hormone therapy (MHT) comprising MP as progestogen for endometrial protection. Tolerability and safety of MP were good. However, there was no study investigating the impact of MP on menopausal scalp hair. In conclusion, delay of skin aging comprises lifestyle adjustment, antioxidants, and several esthetic procedures. In menopausal women, MHT displays beneficial effects on skin aging. There is poor quality but promising scientific evidence for MP displaying anti-aging skin effects in menopausal women. However, good quality studies are needed. SN - 1473-0804 UR - https://www.unboundmedicine.com/medline/citation/33527841/Impact_of_progesterone_on_skin_and_hair_in_menopause___a_comprehensive_review_ L2 - https://www.tandfonline.com/doi/full/10.1080/13697137.2020.1838476 DB - PRIME DP - Unbound Medicine ER -