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The link between nutrition and Alzheimer's disease: from prevention to treatment.
Neurodegener Dis Manag. 2021 04; 11(2):155-166.ND

Abstract

Alzheimer's disease (AD) is the most common cause of dementia. To date, there is no effective pharmacological strategy to slow or stop disease progression. In this context, multiple alternative therapeutic strategies have been investigated for AD. This review addresses the potential role of nutrition interventions in AD prevention and treatment. Nutritional strategies for AD have been based on four pillars: maintaining a healthy weight (i.e., prevention and/or treatment of obesity, especially in midlife and prevention of weight loss in the later stages of AD); correction of nutritional deficiencies; adequate consumption of micronutrients (vitamins and minerals), especially those implicated in the pathways of AD pathophysiology; and microbiota modulation.

Authors+Show Affiliations

Department of Psychiatry & Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX 77054, USA. Departamento de Nutrição, Escola de Enfermagem, Universidade Federal de Minas Gerais, Belo Horizonte, MG, 30130-100, Brazil.Departamento de Nutrição, Escola de Enfermagem, Universidade Federal de Minas Gerais, Belo Horizonte, MG, 30130-100, Brazil. Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, 31270-901, Brazil.Department of Psychiatry & Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX 77054, USA.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

33550870

Citation

Martins, Laís Bhering, et al. "The Link Between Nutrition and Alzheimer's Disease: From Prevention to Treatment." Neurodegenerative Disease Management, vol. 11, no. 2, 2021, pp. 155-166.
Martins LB, Malheiros Silveira AL, Teixeira AL. The link between nutrition and Alzheimer's disease: from prevention to treatment. Neurodegener Dis Manag. 2021;11(2):155-166.
Martins, L. B., Malheiros Silveira, A. L., & Teixeira, A. L. (2021). The link between nutrition and Alzheimer's disease: from prevention to treatment. Neurodegenerative Disease Management, 11(2), 155-166. https://doi.org/10.2217/nmt-2020-0023
Martins LB, Malheiros Silveira AL, Teixeira AL. The Link Between Nutrition and Alzheimer's Disease: From Prevention to Treatment. Neurodegener Dis Manag. 2021;11(2):155-166. PubMed PMID: 33550870.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The link between nutrition and Alzheimer's disease: from prevention to treatment. AU - Martins,Laís Bhering, AU - Malheiros Silveira,Ana Letícia, AU - Teixeira,Antonio Lúcio, Y1 - 2021/02/08/ PY - 2021/2/9/pubmed PY - 2021/2/9/medline PY - 2021/2/8/entrez KW - Alzheimer's disease KW - microbiota KW - nutrition KW - prevention KW - treatment SP - 155 EP - 166 JF - Neurodegenerative disease management JO - Neurodegener Dis Manag VL - 11 IS - 2 N2 - Alzheimer's disease (AD) is the most common cause of dementia. To date, there is no effective pharmacological strategy to slow or stop disease progression. In this context, multiple alternative therapeutic strategies have been investigated for AD. This review addresses the potential role of nutrition interventions in AD prevention and treatment. Nutritional strategies for AD have been based on four pillars: maintaining a healthy weight (i.e., prevention and/or treatment of obesity, especially in midlife and prevention of weight loss in the later stages of AD); correction of nutritional deficiencies; adequate consumption of micronutrients (vitamins and minerals), especially those implicated in the pathways of AD pathophysiology; and microbiota modulation. SN - 1758-2032 UR - https://www.unboundmedicine.com/medline/citation/33550870/The_link_between_nutrition_and_Alzheimer's_disease:_from_prevention_to_treatment_ L2 - https://www.futuremedicine.com/doi/10.2217/nmt-2020-0023?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -
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