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Comparison of Immune Response between SARS, MERS, and COVID-19 Infection, Perspective on Vaccine Design and Development.
Biomed Res Int. 2021; 2021:8870425.BR

Abstract

Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS), and Coronavirus Disease 2019 (COVID-19) infections are the three epidemiological diseases caused by the Coronaviridae family. Perceiving the immune responses in these infections and the escape of viruses could help us design drugs and vaccines for confronting these infections. This review investigates the innate and adaptive immune responses reported in the infections of the three coronaviruses SARS, MERS, and COVID-19. Moreover, the present study can trigger researchers to design and develop new vaccines and drugs based on immune system responses. In conclusion, due to the need for an effective and efficient immune stimulation against coronavirus, a combination of several strategies seems necessary for developing the vaccine.

Links

Publisher Full Text
ncbi.nlm.nih.gov
doi.org
PMC Free PDF

Authors+Show Affiliations

Ansariniya H
Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Seifati SM
Reproductive Immunology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Zaker E
Department of Medical Genetics, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Zare F
Reproductive Immunology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

MeSH

Adaptive ImmunityAnimalsCOVID-19COVID-19 VaccinesCoronavirus InfectionsHumansImmunity, InnateMiddle East Respiratory Syndrome CoronavirusSARS VirusSARS-CoV-2Severe Acute Respiratory Syndrome

Pub Type(s)

Comparative Study
Journal Article
Review

Language

eng

PubMed ID

33564683

Citation

Ansariniya, Hossein, et al. "Comparison of Immune Response Between SARS, MERS, and COVID-19 Infection, Perspective On Vaccine Design and Development." BioMed Research International, vol. 2021, 2021, p. 8870425.
Ansariniya H, Seifati SM, Zaker E, et al. Comparison of Immune Response between SARS, MERS, and COVID-19 Infection, Perspective on Vaccine Design and Development. Biomed Res Int. 2021;2021:8870425.
Ansariniya, H., Seifati, S. M., Zaker, E., & Zare, F. (2021). Comparison of Immune Response between SARS, MERS, and COVID-19 Infection, Perspective on Vaccine Design and Development. BioMed Research International, 2021, 8870425. https://doi.org/10.1155/2021/8870425
Ansariniya H, et al. Comparison of Immune Response Between SARS, MERS, and COVID-19 Infection, Perspective On Vaccine Design and Development. Biomed Res Int. 2021;2021:8870425. PubMed PMID: 33564683.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of Immune Response between SARS, MERS, and COVID-19 Infection, Perspective on Vaccine Design and Development. AU - Ansariniya,Hossein, AU - Seifati,Seyed Mohammad, AU - Zaker,Erfan, AU - Zare,Fateme, Y1 - 2021/01/22/ PY - 2020/09/01/received PY - 2021/01/03/revised PY - 2021/01/11/accepted PY - 2021/2/10/entrez PY - 2021/2/11/pubmed PY - 2021/2/16/medline SP - 8870425 EP - 8870425 JF - BioMed research international JO - Biomed Res Int VL - 2021 N2 - Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS), and Coronavirus Disease 2019 (COVID-19) infections are the three epidemiological diseases caused by the Coronaviridae family. Perceiving the immune responses in these infections and the escape of viruses could help us design drugs and vaccines for confronting these infections. This review investigates the innate and adaptive immune responses reported in the infections of the three coronaviruses SARS, MERS, and COVID-19. Moreover, the present study can trigger researchers to design and develop new vaccines and drugs based on immune system responses. In conclusion, due to the need for an effective and efficient immune stimulation against coronavirus, a combination of several strategies seems necessary for developing the vaccine. SN - 2314-6141 UR - https://www.unboundmedicine.com/medline/citation/33564683/Comparison_of_Immune_Response_between_SARS_MERS_and_COVID_19_Infection_Perspective_on_Vaccine_Design_and_Development_ L2 - https://doi.org/10.1155/2021/8870425 DB - PRIME DP - Unbound Medicine ER -