Tags

Type your tag names separated by a space and hit enter

Mass gatherings: a review of the scope for meningococcal vaccination in the Indian context.
Hum Vaccin Immunother. 2021 07 03; 17(7):2216-2224.HV

Abstract

The risk of meningococcal transmission is increased with crowding and prolonged close proximity between people. There have been numerous invasive meningococcal disease (IMD) outbreaks associated with mass gatherings and other overcrowded situations, including cramped accommodation, such as student and military housing, and refugee camps. In these conditions, IMD outbreaks predominantly affect adolescents and young adults. In this narrative review, we examine the situation in India, where the burden of IMD-related complications is significant but the reported background incidence of IMD is low. However, active surveillance for meningococcal disease is suboptimal and laboratory confirmation of meningococcal strain is near absent, especially in non-outbreak periods. IMD risk factors are prevalent, including frequent mass gatherings and overcrowding combined with a demographically young population. Since overcrowded situations are generally unavoidable, the way forward relies on preventive measures. More widespread meningococcal vaccination and strengthened disease surveillance are likely to be key to this approach.

Authors+Show Affiliations

Pediatrics, ESI-PGIMSR & Model Hospital, New Delhi, India.Pediatrics, Nemcare Superspeciality Hospital, Bhangagarh, Guwahati, and RIGPA Children's Clinic, Guwahati, India.GSK, Rueil-Malmaison, France.GSK, Mumbai, India.GSK, New Delhi, India.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

33605845

Citation

Dubey, Anand P., et al. "Mass Gatherings: a Review of the Scope for Meningococcal Vaccination in the Indian Context." Human Vaccines & Immunotherapeutics, vol. 17, no. 7, 2021, pp. 2216-2224.
Dubey AP, Hazarika RD, Abitbol V, et al. Mass gatherings: a review of the scope for meningococcal vaccination in the Indian context. Hum Vaccin Immunother. 2021;17(7):2216-2224.
Dubey, A. P., Hazarika, R. D., Abitbol, V., Kolhapure, S., & Agrawal, S. (2021). Mass gatherings: a review of the scope for meningococcal vaccination in the Indian context. Human Vaccines & Immunotherapeutics, 17(7), 2216-2224. https://doi.org/10.1080/21645515.2020.1871572
Dubey AP, et al. Mass Gatherings: a Review of the Scope for Meningococcal Vaccination in the Indian Context. Hum Vaccin Immunother. 2021 07 3;17(7):2216-2224. PubMed PMID: 33605845.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Mass gatherings: a review of the scope for meningococcal vaccination in the Indian context. AU - Dubey,Anand P, AU - Hazarika,Rashna Dass, AU - Abitbol,Veronique, AU - Kolhapure,Shafi, AU - Agrawal,Someya, Y1 - 2021/02/19/ PY - 2021/2/20/pubmed PY - 2021/7/6/medline PY - 2021/2/19/entrez KW - Crowd KW - IMD KW - India KW - Neisseria meningitidis KW - mass gathering KW - meningococcal disease KW - outbreak KW - prevention KW - travel KW - vaccination SP - 2216 EP - 2224 JF - Human vaccines & immunotherapeutics JO - Hum Vaccin Immunother VL - 17 IS - 7 N2 - The risk of meningococcal transmission is increased with crowding and prolonged close proximity between people. There have been numerous invasive meningococcal disease (IMD) outbreaks associated with mass gatherings and other overcrowded situations, including cramped accommodation, such as student and military housing, and refugee camps. In these conditions, IMD outbreaks predominantly affect adolescents and young adults. In this narrative review, we examine the situation in India, where the burden of IMD-related complications is significant but the reported background incidence of IMD is low. However, active surveillance for meningococcal disease is suboptimal and laboratory confirmation of meningococcal strain is near absent, especially in non-outbreak periods. IMD risk factors are prevalent, including frequent mass gatherings and overcrowding combined with a demographically young population. Since overcrowded situations are generally unavoidable, the way forward relies on preventive measures. More widespread meningococcal vaccination and strengthened disease surveillance are likely to be key to this approach. SN - 2164-554X UR - https://www.unboundmedicine.com/medline/citation/33605845/Mass_gatherings:_a_review_of_the_scope_for_meningococcal_vaccination_in_the_Indian_context_ L2 - https://www.tandfonline.com/doi/full/10.1080/21645515.2020.1871572 DB - PRIME DP - Unbound Medicine ER -