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[Detection of Ciguatoxins from Fish Introduced into a Wholesale Market in Japan].
Shokuhin Eiseigaku Zasshi. 2021; 62(1):8-13.SE

Abstract

Ciguatera fish poisoning (CFP), one of the most frequently occurring seafood poisonings due to marine finfish consumption, mainly affects the tropical and subtropical Indo-Pacific region and the Caribbean Sea. The principal class of toxins, ciguatoxins (CTXs) from the Pacific, includes more than 20 derivatives and are classified into two groups, CTX1B and CTX3C congeners, based on their skeletal structures. As part of risk management of CFP by the Japanese government, the import of certain species of fish into Japan is prohibited. Additionally, local governments recommend rejecting certain fish species caught in Japan. In this study, we used LC-MS/MS to analyze CTXs from 18 fish specimens belonging to 7 species that had been brought to a wholesale market but were disapproved for sale because of their potential danger of CFP. CTXs were detected in four specimens of Lutjanus bohar and one specimen of Variola louti. It was estimated that the two most poisonous specimens (no. 5: 0.348 μg/kg, no. 8: 0.362 μg/kg) had a toxicity of 0.05 MU/g. Consumption of 200 g of flesh from these fish could cause CFP. Thus, the guidance of the local government to disallow the sale of these fish species in the market contributed to the prevention of CFP.Only CTX1B congeners were detected in L. bohar (specimen no. 5), which had no record of the area where it captured from. It is presumed that the origin of specimen no. 5 was the same as that of the Okinawan L. bohar because the CTX compositions were similar. In two specimens (nos. 6 and 8) from Wakayama, both CTX1B and CTX3C congeners were detected. This is the first report to reveal the CTX profile in fish collected off the Honshu island in Japan.

Authors+Show Affiliations

National Institute of Health Sciences.National Institute of Health Sciences. Graduate School of Science and Technology, Teikyo University of Science.National Institute of Health Sciences.Tokyo Metropolitan Institute of Public Health.Fuculty of Life & Environmental Sciences, Teikyo University of Science.Tama Laboratory, Japan Food Research Laboratories.National Institute of Health Sciences.

Pub Type(s)

Journal Article

Language

jpn

PubMed ID

33658463

Citation

Oshiro, Naomasa, et al. "[Detection of Ciguatoxins From Fish Introduced Into a Wholesale Market in Japan]." Shokuhin Eiseigaku Zasshi. Journal of the Food Hygienic Society of Japan, vol. 62, no. 1, 2021, pp. 8-13.
Oshiro N, Tomikawa T, Kuniyoshi K, et al. [Detection of Ciguatoxins from Fish Introduced into a Wholesale Market in Japan]. Shokuhin Eiseigaku Zasshi. 2021;62(1):8-13.
Oshiro, N., Tomikawa, T., Kuniyoshi, K., Kimura, K., Kojima, T., Yasumoto, T., & Asakura, H. (2021). [Detection of Ciguatoxins from Fish Introduced into a Wholesale Market in Japan]. Shokuhin Eiseigaku Zasshi. Journal of the Food Hygienic Society of Japan, 62(1), 8-13. https://doi.org/10.3358/shokueishi.62.8
Oshiro N, et al. [Detection of Ciguatoxins From Fish Introduced Into a Wholesale Market in Japan]. Shokuhin Eiseigaku Zasshi. 2021;62(1):8-13. PubMed PMID: 33658463.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Detection of Ciguatoxins from Fish Introduced into a Wholesale Market in Japan]. AU - Oshiro,Naomasa, AU - Tomikawa,Takumi, AU - Kuniyoshi,Kyoko, AU - Kimura,Keisuke, AU - Kojima,Takashi, AU - Yasumoto,Takeshi, AU - Asakura,Hiroshi, PY - 2021/3/4/entrez PY - 2021/3/5/pubmed PY - 2021/3/6/medline KW - Lutjanus bohar KW - Variola louti KW - ciguatoxin SP - 8 EP - 13 JF - Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan JO - Shokuhin Eiseigaku Zasshi VL - 62 IS - 1 N2 - Ciguatera fish poisoning (CFP), one of the most frequently occurring seafood poisonings due to marine finfish consumption, mainly affects the tropical and subtropical Indo-Pacific region and the Caribbean Sea. The principal class of toxins, ciguatoxins (CTXs) from the Pacific, includes more than 20 derivatives and are classified into two groups, CTX1B and CTX3C congeners, based on their skeletal structures. As part of risk management of CFP by the Japanese government, the import of certain species of fish into Japan is prohibited. Additionally, local governments recommend rejecting certain fish species caught in Japan. In this study, we used LC-MS/MS to analyze CTXs from 18 fish specimens belonging to 7 species that had been brought to a wholesale market but were disapproved for sale because of their potential danger of CFP. CTXs were detected in four specimens of Lutjanus bohar and one specimen of Variola louti. It was estimated that the two most poisonous specimens (no. 5: 0.348 μg/kg, no. 8: 0.362 μg/kg) had a toxicity of 0.05 MU/g. Consumption of 200 g of flesh from these fish could cause CFP. Thus, the guidance of the local government to disallow the sale of these fish species in the market contributed to the prevention of CFP.Only CTX1B congeners were detected in L. bohar (specimen no. 5), which had no record of the area where it captured from. It is presumed that the origin of specimen no. 5 was the same as that of the Okinawan L. bohar because the CTX compositions were similar. In two specimens (nos. 6 and 8) from Wakayama, both CTX1B and CTX3C congeners were detected. This is the first report to reveal the CTX profile in fish collected off the Honshu island in Japan. SN - 0015-6426 UR - https://www.unboundmedicine.com/medline/citation/33658463/[Detection_of_Ciguatoxins_from_Fish_Introduced_into_a_Wholesale_Market_in_Japan]_ L2 - https://dx.doi.org/10.3358/shokueishi.62.8 DB - PRIME DP - Unbound Medicine ER -