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Necrobiotic xanthogranuloma: a case without paraproteinemia but with transepithelial elimination.
J Cutan Pathol. 1988 Apr; 15(2):116-9.JC

Abstract

We report a female patient, now aged 60, followed for 20 years for lesions originally diagnosed as necrobiosis lipoidica diabeticorum. In fact, the anatomical and clinical features of her disorder correspond to the new entity described as necrobiotic xanthogranuloma. Two elements distinguish this from earlier cases: 1) two examinations failed to reveal paraproteinemia; 2) there was transepithelial elimination of cholesterol crystals and degenerated xanthomatous cell debris via hair follicles. This demonstrates the characteristic histology of the disorder and indicates that the diagnosis of necrobiotic xanthogranuloma should be considered even in the absence of paraproteinemia.

Authors+Show Affiliations

Dermatology Service, Purpan Hôpital, Toulouse, France.No affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

3372788

Citation

Dupré, A, and R Viraben. "Necrobiotic Xanthogranuloma: a Case Without Paraproteinemia but With Transepithelial Elimination." Journal of Cutaneous Pathology, vol. 15, no. 2, 1988, pp. 116-9.
Dupré A, Viraben R. Necrobiotic xanthogranuloma: a case without paraproteinemia but with transepithelial elimination. J Cutan Pathol. 1988;15(2):116-9.
Dupré, A., & Viraben, R. (1988). Necrobiotic xanthogranuloma: a case without paraproteinemia but with transepithelial elimination. Journal of Cutaneous Pathology, 15(2), 116-9.
Dupré A, Viraben R. Necrobiotic Xanthogranuloma: a Case Without Paraproteinemia but With Transepithelial Elimination. J Cutan Pathol. 1988;15(2):116-9. PubMed PMID: 3372788.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Necrobiotic xanthogranuloma: a case without paraproteinemia but with transepithelial elimination. AU - Dupré,A, AU - Viraben,R, PY - 1988/4/1/pubmed PY - 1988/4/1/medline PY - 1988/4/1/entrez SP - 116 EP - 9 JF - Journal of cutaneous pathology JO - J. Cutan. Pathol. VL - 15 IS - 2 N2 - We report a female patient, now aged 60, followed for 20 years for lesions originally diagnosed as necrobiosis lipoidica diabeticorum. In fact, the anatomical and clinical features of her disorder correspond to the new entity described as necrobiotic xanthogranuloma. Two elements distinguish this from earlier cases: 1) two examinations failed to reveal paraproteinemia; 2) there was transepithelial elimination of cholesterol crystals and degenerated xanthomatous cell debris via hair follicles. This demonstrates the characteristic histology of the disorder and indicates that the diagnosis of necrobiotic xanthogranuloma should be considered even in the absence of paraproteinemia. SN - 0303-6987 UR - https://www.unboundmedicine.com/medline/citation/3372788/Necrobiotic_xanthogranuloma:_a_case_without_paraproteinemia_but_with_transepithelial_elimination_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0303-6987&date=1988&volume=15&issue=2&spage=116 DB - PRIME DP - Unbound Medicine ER -