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Factors associated with the willingness and acceptance of SARS-CoV-2 vaccine from adult subjects in China.
Hum Vaccin Immunother. 2021 08 03; 17(8):2405-2414.HV

Abstract

Aim: We aimed to investigate factors affecting the willingness and acceptance of the SARS-CoV-2 vaccination among adults in China and sources of knowledge about the vaccine.Methods: A cross-sectional, web-based survey was conducted from September 8th to 15th, 2020, comprising of 23 questions. Binary logistic regression analysis was performed to examine factors associated with vaccination willingness and acceptance.Results: A total of 983 questionnaires were included and 81.3% of the participants were willing to receive the SARS-CoV-2 vaccine. With a "bachelor degree or above" (OR = 0.56, p = 0.020) and believing that the vaccine would not cause SARS-CoV-2 infection (OR = 0.50, p = 0.003) were associated with an increased willingness. Aged :30 years (OR = 0.38, p = 0.001), and believing that the vaccine would not cause SARS-CoV-2 infection (OR = 0.52, p = 0.004) were associated with higher acceptance; while from Henan province (OR = 2.49, p < 0.001), not willing to vaccinate (OR = 3.86, p < 0.001), not suffering from chronic diseases (OR = 2.25, p = 0.013), and thinking it was not safe and effective in preventing COVID-19 (OR = 1.94, p = 0.001) were correlated with a lower acceptance.Conclusions: In conclusion, age, education, and vaccine perception might be key factors affecting the vaccine willingness and acceptance. Triggering positive perception of vaccine, especially by targeting those aged <30 years, or those with below bachelor degree, or without chronic diseases might be key approaches for improving the willingness and acceptance of vaccine in China.

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Authors+Show Affiliations

Liu D
Department of Nutrition and Food Hygiene, School of Public Health, Soochow University, Suzhou, China.
Luo L
Department of Nutrition and Food Hygiene, School of Public Health, Soochow University, Suzhou, China.
Xie F
Physical Examination Center, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, China.
Yu Z
College of Public Health, Zhengzhou University, Zhengzhou, China.
Ma ZF
Department of Health and Environmental Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, China.
Wang Y
Physical Examination Center, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, China.
Wan Z
Department of Nutrition and Food Hygiene, School of Public Health, Soochow University, Suzhou, China. College of Public Health, Zhengzhou University, Zhengzhou, China.

MeSH

AdultCOVID-19COVID-19 VaccinesChinaCross-Sectional StudiesHumansSARS-CoV-2VaccinationVaccines

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

33759691

Citation

Liu, Di, et al. "Factors Associated With the Willingness and Acceptance of SARS-CoV-2 Vaccine From Adult Subjects in China." Human Vaccines & Immunotherapeutics, vol. 17, no. 8, 2021, pp. 2405-2414.
Liu D, Luo L, Xie F, et al. Factors associated with the willingness and acceptance of SARS-CoV-2 vaccine from adult subjects in China. Hum Vaccin Immunother. 2021;17(8):2405-2414.
Liu, D., Luo, L., Xie, F., Yu, Z., Ma, Z. F., Wang, Y., & Wan, Z. (2021). Factors associated with the willingness and acceptance of SARS-CoV-2 vaccine from adult subjects in China. Human Vaccines & Immunotherapeutics, 17(8), 2405-2414. https://doi.org/10.1080/21645515.2021.1899732
Liu D, et al. Factors Associated With the Willingness and Acceptance of SARS-CoV-2 Vaccine From Adult Subjects in China. Hum Vaccin Immunother. 2021 08 3;17(8):2405-2414. PubMed PMID: 33759691.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Factors associated with the willingness and acceptance of SARS-CoV-2 vaccine from adult subjects in China. AU - Liu,Di, AU - Luo,Lan, AU - Xie,Fangfei, AU - Yu,Zengli, AU - Ma,Zheng Feei, AU - Wang,Yun, AU - Wan,Zhongxiao, Y1 - 2021/03/24/ PY - 2021/3/25/pubmed PY - 2021/9/30/medline PY - 2021/3/24/entrez KW - COVID-19 KW - SARS-CoV-2 vaccine KW - acceptance KW - cross-section study KW - willingness SP - 2405 EP - 2414 JF - Human vaccines & immunotherapeutics JO - Hum Vaccin Immunother VL - 17 IS - 8 N2 - Aim: We aimed to investigate factors affecting the willingness and acceptance of the SARS-CoV-2 vaccination among adults in China and sources of knowledge about the vaccine.Methods: A cross-sectional, web-based survey was conducted from September 8th to 15th, 2020, comprising of 23 questions. Binary logistic regression analysis was performed to examine factors associated with vaccination willingness and acceptance.Results: A total of 983 questionnaires were included and 81.3% of the participants were willing to receive the SARS-CoV-2 vaccine. With a "bachelor degree or above" (OR = 0.56, p = 0.020) and believing that the vaccine would not cause SARS-CoV-2 infection (OR = 0.50, p = 0.003) were associated with an increased willingness. Aged :30 years (OR = 0.38, p = 0.001), and believing that the vaccine would not cause SARS-CoV-2 infection (OR = 0.52, p = 0.004) were associated with higher acceptance; while from Henan province (OR = 2.49, p < 0.001), not willing to vaccinate (OR = 3.86, p < 0.001), not suffering from chronic diseases (OR = 2.25, p = 0.013), and thinking it was not safe and effective in preventing COVID-19 (OR = 1.94, p = 0.001) were correlated with a lower acceptance.Conclusions: In conclusion, age, education, and vaccine perception might be key factors affecting the vaccine willingness and acceptance. Triggering positive perception of vaccine, especially by targeting those aged <30 years, or those with below bachelor degree, or without chronic diseases might be key approaches for improving the willingness and acceptance of vaccine in China. SN - 2164-554X UR - https://www.unboundmedicine.com/medline/citation/33759691/Factors_associated_with_the_willingness_and_acceptance_of_SARS_CoV_2_vaccine_from_adult_subjects_in_China_ DB - PRIME DP - Unbound Medicine ER -