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Interstitial lung abnormality (ILA) and nonspecific interstitial pneumonia (NSIP).
Eur J Radiol Open. 2021; 8:100336.EJ

Abstract

This review article aims to address mysteries existing between Interstitial Lung Abnormality (ILA) and Nonspecific Interstitial Pneumonia (NSIP). The concept and definition of ILA are based upon CT scans from multiple large-scale cohort studies, whereas the concept and definition of NSIP originally derived from pathology with evolution to multi-disciplinary diagnosis. NSIP is the diagnosis as Interstitial Lung Disease (ILD) with clinical significance, whereas only a part of subjects with ILA have clinically significant ILD. Eventually, both ILA and NSIP must be understood in the context of chronic fibrosing ILD and progressive ILD, which remains to be further investigated.

Authors+Show Affiliations

Center for Pulmonary Functional Imaging, Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 8128582, Japan.Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine (SKKU-SOM), Seoul, Republic of Korea.Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine (SKKU-SOM), Seoul, Republic of Korea.Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine (SKKU-SOM), Seoul, Republic of Korea.Pulmonary & Mediastinal Pathology, Department of Defense, The Joint Pathology Center, Silver Spring, MD, USA.Center for Pulmonary Functional Imaging, Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

33796637

Citation

Hino, Takuya, et al. "Interstitial Lung Abnormality (ILA) and Nonspecific Interstitial Pneumonia (NSIP)." European Journal of Radiology Open, vol. 8, 2021, p. 100336.
Hino T, Lee KS, Yoo H, et al. Interstitial lung abnormality (ILA) and nonspecific interstitial pneumonia (NSIP). Eur J Radiol Open. 2021;8:100336.
Hino, T., Lee, K. S., Yoo, H., Han, J., Franks, T. J., & Hatabu, H. (2021). Interstitial lung abnormality (ILA) and nonspecific interstitial pneumonia (NSIP). European Journal of Radiology Open, 8, 100336. https://doi.org/10.1016/j.ejro.2021.100336
Hino T, et al. Interstitial Lung Abnormality (ILA) and Nonspecific Interstitial Pneumonia (NSIP). Eur J Radiol Open. 2021;8:100336. PubMed PMID: 33796637.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Interstitial lung abnormality (ILA) and nonspecific interstitial pneumonia (NSIP). AU - Hino,Takuya, AU - Lee,Kyung Soo, AU - Yoo,Hongseok, AU - Han,Joungho, AU - Franks,Teri J, AU - Hatabu,Hiroto, Y1 - 2021/03/16/ PY - 2021/03/05/received PY - 2021/03/08/accepted PY - 2021/4/2/entrez PY - 2021/4/3/pubmed PY - 2021/4/3/medline KW - AIP, acute interstitial pneumonia KW - ATS/ERS, American Thoracic Society/European Respiratory Society KW - BIP, bronchiolitis obliterans with interstitial pneumonia KW - BOOP, bronchiolitis obliterans organizing pneumonia KW - CT KW - CTD, connective tissue disease KW - Connective tissue disease (CTD) KW - DIP, desquamative interstitial pneumonia KW - GGO, ground-glass opacities KW - GIP, giant cell interstitial pneumonia KW - HRCT KW - HRCT, high-resolution CT KW - IIP, idiopathic interstitial pneumonia KW - ILA, interstitial lung abnormality KW - ILD, interstitial lung disease KW - Interstitial lung abnormality (ILA) KW - Interstitial lung disease (ILD) KW - LIP, lymphoid interstitial pneumonia KW - NSIP, nonspecific interstitial pneumonia KW - Nonspecific interstitial pneumonia (NSIP) KW - Pulmonary fibrosis KW - RB-ILD, respiratory bronchiolitis-associated interstitial lung disease KW - UIP, usual interstitial pneumonia KW - fNSIP, fibrosing nonspecific interstitial pneumonia SP - 100336 EP - 100336 JF - European journal of radiology open JO - Eur J Radiol Open VL - 8 N2 - This review article aims to address mysteries existing between Interstitial Lung Abnormality (ILA) and Nonspecific Interstitial Pneumonia (NSIP). The concept and definition of ILA are based upon CT scans from multiple large-scale cohort studies, whereas the concept and definition of NSIP originally derived from pathology with evolution to multi-disciplinary diagnosis. NSIP is the diagnosis as Interstitial Lung Disease (ILD) with clinical significance, whereas only a part of subjects with ILA have clinically significant ILD. Eventually, both ILA and NSIP must be understood in the context of chronic fibrosing ILD and progressive ILD, which remains to be further investigated. SN - 2352-0477 UR - https://www.unboundmedicine.com/medline/citation/33796637/Interstitial_lung_abnormality__ILA__and_nonspecific_interstitial_pneumonia__NSIP__ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/33796637/ DB - PRIME DP - Unbound Medicine ER -
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