Tags

Type your tag names separated by a space and hit enter

[Effect of acupuncture at Tiaoshen acupoints on hyperarousal state in chronic insomnia].
Zhongguo Zhen Jiu. 2021 Mar 12; 41(3):263-7.ZZ

Abstract

OBJECTIVE

To observe the clinical effect of acupuncture at Tiaoshen (regulating the spirit) acupoints on chronic insomnia and hyperarousal state, and explore its possible mechanism.

METHODS

A total of 60 patients with chronic insomnia were randomly divided into an acupuncture group (30 cases, 1 case dropped off) and a sham acupuncture group (30 cases, 1 cases dropped off). Both groups were given basic sleep health education. The acupuncture group was treated with acupuncture at Tiaoshen acupoints including Baihui (GV 20), Shenting (GV 24), Yintang (GV 29), Shenmen (HT 7) and Sanyinjiao (SP 6). The sham acupuncture group was treated with non-effective point shallow acupuncture. Both groups were treated once every other day, 3 times a week for 4 weeks. The Pittsburgh sleep quality index (PSQI) score, pre-sleep arousal scale (PSAS) score, hyperarousal scale (HAS) score, and serum gamma-aminobutyric acid (GABA) level before and after treatment were compared between the two groups.

RESULTS

Compared before treatment, the sleep quality, time to fall asleep, sleep time, sleep efficiency, sleep disturbance, daytime dysfunction scores and total score of PSQI, various scores and total score of PSAS, and HAS score in the acupuncture group after treatment were decreased (P<0.05, P<0.01); in the sham acupuncture group, the time to fall asleep, daytime dysfunction scores and total score of PSQI, and cognitive arousal score of PSAS after treatment were decreased (P<0.05). After treatment, the sleep quality, time to fall asleep, sleep time, sleep efficiency, sleep disturbance, daytime dysfunction scores and total score of PSQI, various scores and total score of PSAS, and HAS score in the acupuncture group were lower than those in the sham acupuncture group (P<0.05, P<0.01). Compared before treatment, the serum GABA level in the acupuncture group were increased (P<0.05), and the serum GABA level in the acupuncture group was higher than that in the sham acupuncture group after treatment (P<0.05).

CONCLUSION

Acupuncture at Tiaoshen acupoints can obviously improve the sleep and hyperarousal state of patients with chronic insomnia, and up-regulating serum GABA content is one of its possible mechanisms.

Authors+Show Affiliations

School of Acupuncture-Moxibustion and Tuina/Regimen and Rehabilitation, Nanjing University of Chinese Medicine, Nanjing 210046, Jiangsu Province, China.Department of Acupuncture-Moxibustion and Rehabilitation, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province.Department of Acupuncture-Moxibustion and Rehabilitation, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province.Physical Examination Center, Affiliated Hospital of Nanjing University of Chinese Medicine.Department of Acupuncture-Moxibustion and Rehabilitation, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province.Department of Acupuncture-Moxibustion and Rehabilitation, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province.Department of Acupuncture-Moxibustion and Rehabilitation, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province.Department of Acupuncture-Moxibustion and Rehabilitation, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province.Department of Acupuncture-Moxibustion and Rehabilitation, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province.

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

chi

PubMed ID

33798307

Citation

Xi, Han-Qing, et al. "[Effect of Acupuncture at Tiaoshen Acupoints On Hyperarousal State in Chronic Insomnia]." Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, vol. 41, no. 3, 2021, pp. 263-7.
Xi HQ, Wu WZ, Liu CY, et al. [Effect of acupuncture at Tiaoshen acupoints on hyperarousal state in chronic insomnia]. Zhongguo Zhen Jiu. 2021;41(3):263-7.
Xi, H. Q., Wu, W. Z., Liu, C. Y., Wang, X. Q., Qin, S., Zhao, Y. N., Zheng, S. Y., Li, J. H., & Wan, Q. Y. (2021). [Effect of acupuncture at Tiaoshen acupoints on hyperarousal state in chronic insomnia]. Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, 41(3), 263-7. https://doi.org/10.13703/j.0255-2930.20200303-k0004
Xi HQ, et al. [Effect of Acupuncture at Tiaoshen Acupoints On Hyperarousal State in Chronic Insomnia]. Zhongguo Zhen Jiu. 2021 Mar 12;41(3):263-7. PubMed PMID: 33798307.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Effect of acupuncture at Tiaoshen acupoints on hyperarousal state in chronic insomnia]. AU - Xi,Han-Qing, AU - Wu,Wen-Zhong, AU - Liu,Cheng-Yong, AU - Wang,Xiao-Qiu, AU - Qin,Shan, AU - Zhao,Ya-Nan, AU - Zheng,Shi-Yu, AU - Li,Jia-Huan, AU - Wan,Qing-Yun, PY - 2021/4/2/entrez PY - 2021/4/3/pubmed PY - 2021/4/7/medline KW - acupuncture KW - chronic insomnia KW - gamma-aminobutyric acid (GABA) KW - hyperarousal state KW - randomized controlled trial (RCT) SP - 263 EP - 7 JF - Zhongguo zhen jiu = Chinese acupuncture & moxibustion JO - Zhongguo Zhen Jiu VL - 41 IS - 3 N2 - OBJECTIVE: To observe the clinical effect of acupuncture at Tiaoshen (regulating the spirit) acupoints on chronic insomnia and hyperarousal state, and explore its possible mechanism. METHODS: A total of 60 patients with chronic insomnia were randomly divided into an acupuncture group (30 cases, 1 case dropped off) and a sham acupuncture group (30 cases, 1 cases dropped off). Both groups were given basic sleep health education. The acupuncture group was treated with acupuncture at Tiaoshen acupoints including Baihui (GV 20), Shenting (GV 24), Yintang (GV 29), Shenmen (HT 7) and Sanyinjiao (SP 6). The sham acupuncture group was treated with non-effective point shallow acupuncture. Both groups were treated once every other day, 3 times a week for 4 weeks. The Pittsburgh sleep quality index (PSQI) score, pre-sleep arousal scale (PSAS) score, hyperarousal scale (HAS) score, and serum gamma-aminobutyric acid (GABA) level before and after treatment were compared between the two groups. RESULTS: Compared before treatment, the sleep quality, time to fall asleep, sleep time, sleep efficiency, sleep disturbance, daytime dysfunction scores and total score of PSQI, various scores and total score of PSAS, and HAS score in the acupuncture group after treatment were decreased (P<0.05, P<0.01); in the sham acupuncture group, the time to fall asleep, daytime dysfunction scores and total score of PSQI, and cognitive arousal score of PSAS after treatment were decreased (P<0.05). After treatment, the sleep quality, time to fall asleep, sleep time, sleep efficiency, sleep disturbance, daytime dysfunction scores and total score of PSQI, various scores and total score of PSAS, and HAS score in the acupuncture group were lower than those in the sham acupuncture group (P<0.05, P<0.01). Compared before treatment, the serum GABA level in the acupuncture group were increased (P<0.05), and the serum GABA level in the acupuncture group was higher than that in the sham acupuncture group after treatment (P<0.05). CONCLUSION: Acupuncture at Tiaoshen acupoints can obviously improve the sleep and hyperarousal state of patients with chronic insomnia, and up-regulating serum GABA content is one of its possible mechanisms. SN - 0255-2930 UR - https://www.unboundmedicine.com/medline/citation/33798307/[Effect_of_acupuncture_at_Tiaoshen_acupoints_on_hyperarousal_state_in_chronic_insomnia]_ L2 - https://medlineplus.gov/insomnia.html DB - PRIME DP - Unbound Medicine ER -