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Pulsed Broad-Spectrum UV Light Effectively Inactivates SARS-CoV-2 on Multiple Surfaces and N95 Material.
Viruses. 2021 03 11; 13(3)V

Abstract

The ongoing SARS-CoV-2 pandemic has resulted in an increased need for technologies capable of efficiently disinfecting public spaces as well as personal protective equipment. UV light disinfection is a well-established method for inactivating respiratory viruses. Here, we have determined that broad-spectrum, pulsed UV light is effective at inactivating SARS-CoV-2 on multiple surfaces in vitro. For hard, non-porous surfaces, we observed that SARS-CoV-2 was inactivated to undetectable levels on plastic and glass with a UV dose of 34.9 mJ/cm2 and stainless steel with a dose of 52.5 mJ/cm2. We also observed that broad-spectrum, pulsed UV light is effective at reducing SARS-CoV-2 on N95 respirator material to undetectable levels with a dose of 103 mJ/cm2. We included UV dosimeter cards that provide a colorimetric readout of UV dose and demonstrated their utility as a means to confirm desired levels of exposure were reached. Together, the results presented here demonstrate that broad-spectrum, pulsed UV light is an effective technology for the in vitro inactivation of SARS-CoV-2 on multiple surfaces.

Authors+Show Affiliations

Center for Microbial Pathogenesis, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303, USA.Center for Microbial Pathogenesis, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303, USA.Center for Microbial Pathogenesis, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303, USA.

Pub Type(s)

Evaluation Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

33799842

Citation

Jureka, Alexander S., et al. "Pulsed Broad-Spectrum UV Light Effectively Inactivates SARS-CoV-2 On Multiple Surfaces and N95 Material." Viruses, vol. 13, no. 3, 2021.
Jureka AS, Williams CG, Basler CF. Pulsed Broad-Spectrum UV Light Effectively Inactivates SARS-CoV-2 on Multiple Surfaces and N95 Material. Viruses. 2021;13(3).
Jureka, A. S., Williams, C. G., & Basler, C. F. (2021). Pulsed Broad-Spectrum UV Light Effectively Inactivates SARS-CoV-2 on Multiple Surfaces and N95 Material. Viruses, 13(3). https://doi.org/10.3390/v13030460
Jureka AS, Williams CG, Basler CF. Pulsed Broad-Spectrum UV Light Effectively Inactivates SARS-CoV-2 On Multiple Surfaces and N95 Material. Viruses. 2021 03 11;13(3) PubMed PMID: 33799842.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pulsed Broad-Spectrum UV Light Effectively Inactivates SARS-CoV-2 on Multiple Surfaces and N95 Material. AU - Jureka,Alexander S, AU - Williams,Caroline G, AU - Basler,Christopher F, Y1 - 2021/03/11/ PY - 2021/02/14/received PY - 2021/03/02/revised PY - 2021/03/09/accepted PY - 2021/4/3/entrez PY - 2021/4/4/pubmed PY - 2021/4/20/medline KW - COVID-19 KW - SARS-CoV-2 KW - coronavirus KW - inactivation KW - ultraviolet JF - Viruses JO - Viruses VL - 13 IS - 3 N2 - The ongoing SARS-CoV-2 pandemic has resulted in an increased need for technologies capable of efficiently disinfecting public spaces as well as personal protective equipment. UV light disinfection is a well-established method for inactivating respiratory viruses. Here, we have determined that broad-spectrum, pulsed UV light is effective at inactivating SARS-CoV-2 on multiple surfaces in vitro. For hard, non-porous surfaces, we observed that SARS-CoV-2 was inactivated to undetectable levels on plastic and glass with a UV dose of 34.9 mJ/cm2 and stainless steel with a dose of 52.5 mJ/cm2. We also observed that broad-spectrum, pulsed UV light is effective at reducing SARS-CoV-2 on N95 respirator material to undetectable levels with a dose of 103 mJ/cm2. We included UV dosimeter cards that provide a colorimetric readout of UV dose and demonstrated their utility as a means to confirm desired levels of exposure were reached. Together, the results presented here demonstrate that broad-spectrum, pulsed UV light is an effective technology for the in vitro inactivation of SARS-CoV-2 on multiple surfaces. SN - 1999-4915 UR - https://www.unboundmedicine.com/medline/citation/33799842/Pulsed_Broad_Spectrum_UV_Light_Effectively_Inactivates_SARS_CoV_2_on_Multiple_Surfaces_and_N95_Material_ L2 - https://www.mdpi.com/resolver?pii=v13030460 DB - PRIME DP - Unbound Medicine ER -