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The epidemiology of varicose veins: the Framingham Study.
Am J Prev Med 1988 Mar-Apr; 4(2):96-101AJ

Abstract

The epidemiology of varicose veins was examined in 3,822 adults in the Framingham Study. Findings indicate that the incidence of varicose veins is higher among women than men, with no clear age differences. Compared to women without varicose veins, women with varicose veins were more often obese (p less than .01), had lower levels of physical activity (p less than .001) and higher systolic blood pressure (p less than .001), and were older at menopause (p less than .001). Women who reported spending eight or more hours in an average day in sedentary activities (sitting or standing) also had a significantly higher incidence of varicose veins than those who spent four or fewer hours a day in such activities (p less than .05). For men, varicose veins coexisted with lower levels of physical activity (p less than .05) and higher smoking rates (p less than .05). While men and women with varicose veins had a higher incidence of atherosclerotic cardiovascular disease than those without varicose veins, only the excess risk of coronary heart disease in women was statistically significant (p less than .05). However, this finding was not significant after controlling for body mass and systolic blood pressure. These results suggest that increased physical activity and weight control may help prevent varicose veins among adults at high risk, and reduce the overall risk of atherosclerotic cardiovascular disease as well.

Authors+Show Affiliations

Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Evans Research Foundation, Massachusetts.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

3395496

Citation

Brand, F N., et al. "The Epidemiology of Varicose Veins: the Framingham Study." American Journal of Preventive Medicine, vol. 4, no. 2, 1988, pp. 96-101.
Brand FN, Dannenberg AL, Abbott RD, et al. The epidemiology of varicose veins: the Framingham Study. Am J Prev Med. 1988;4(2):96-101.
Brand, F. N., Dannenberg, A. L., Abbott, R. D., & Kannel, W. B. (1988). The epidemiology of varicose veins: the Framingham Study. American Journal of Preventive Medicine, 4(2), pp. 96-101.
Brand FN, et al. The Epidemiology of Varicose Veins: the Framingham Study. Am J Prev Med. 1988;4(2):96-101. PubMed PMID: 3395496.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The epidemiology of varicose veins: the Framingham Study. AU - Brand,F N, AU - Dannenberg,A L, AU - Abbott,R D, AU - Kannel,W B, PY - 1988/3/1/pubmed PY - 1988/3/1/medline PY - 1988/3/1/entrez SP - 96 EP - 101 JF - American journal of preventive medicine JO - Am J Prev Med VL - 4 IS - 2 N2 - The epidemiology of varicose veins was examined in 3,822 adults in the Framingham Study. Findings indicate that the incidence of varicose veins is higher among women than men, with no clear age differences. Compared to women without varicose veins, women with varicose veins were more often obese (p less than .01), had lower levels of physical activity (p less than .001) and higher systolic blood pressure (p less than .001), and were older at menopause (p less than .001). Women who reported spending eight or more hours in an average day in sedentary activities (sitting or standing) also had a significantly higher incidence of varicose veins than those who spent four or fewer hours a day in such activities (p less than .05). For men, varicose veins coexisted with lower levels of physical activity (p less than .05) and higher smoking rates (p less than .05). While men and women with varicose veins had a higher incidence of atherosclerotic cardiovascular disease than those without varicose veins, only the excess risk of coronary heart disease in women was statistically significant (p less than .05). However, this finding was not significant after controlling for body mass and systolic blood pressure. These results suggest that increased physical activity and weight control may help prevent varicose veins among adults at high risk, and reduce the overall risk of atherosclerotic cardiovascular disease as well. SN - 0749-3797 UR - https://www.unboundmedicine.com/medline/citation/3395496/The_epidemiology_of_varicose_veins:_the_Framingham_Study_ L2 - https://ClinicalTrials.gov/search/term=3395496 [PUBMED-IDS] DB - PRIME DP - Unbound Medicine ER -