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Preparation of molecularly imprinted polymer with class-specific recognition for determination of 29 sulfonylurea herbicides in agro-products.
J Chromatogr A. 2021 Jun 21; 1647:462143.JC

Abstract

Molecularly imprinting polymers with high selectivity toward 29 sulfonylurea herbicides were synthesized by precipitation polymerization, using metsulfuron-methyl and chlorsulfuron as the template molecule, 4-vinylpyridine as the function monomer, divinylbenzene as the crosslinking agent, and acetonitrile as porogen. The imprinted polymers were characterized and measured by scanning electron microscopy (SEM) and equilibrium adsorption experiments. The molecularly imprinted polymers displayed specific recognition for the tested 29 sulfonylurea herbicides, and the maximum apparent binding capacity was found to be 18.81 mg/g. The synthesized polymer was used as a solid-phase extraction (SPE) column coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) for determination of the tested analytes in agro-products. Within the range of 2-100 μg/L, the tested analytes have achieved a good linear association with correlation coefficient (R2) > 0.999. The calculated limits of detection (LODs, S/N=3) as along with limits of quantification (LOQs, S/N=10) were in the ranges of 0.005-0.07 μg/L and 0.018-0.23 μg/L, respectively. Under different spiking levels, the recovery rates were ranged from 74.8% - 110.5%, and the relative standard deviation (RSDs) were < 5.3%. Finally, the feasibility of the proposed methodology was successfully applied for detection of sulfonylurea herbicides in crops, vegetables, and oils samples.

Authors+Show Affiliations

Institute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Science/Key Laboratory of Agro-Products Quality and Safety of Chinese Ministry of Agriculture, Beijing 100081, P. R. China.Tibetan Inspection and Testing Center for Agricultural Product Quality and Safety, Lhasa, 850000, P.R. China.Institute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Science/Key Laboratory of Agro-Products Quality and Safety of Chinese Ministry of Agriculture, Beijing 100081, P. R. China.Institute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Science/Key Laboratory of Agro-Products Quality and Safety of Chinese Ministry of Agriculture, Beijing 100081, P. R. China.Institute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Science/Key Laboratory of Agro-Products Quality and Safety of Chinese Ministry of Agriculture, Beijing 100081, P. R. China.Institute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Science/Key Laboratory of Agro-Products Quality and Safety of Chinese Ministry of Agriculture, Beijing 100081, P. R. China.Institute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Science/Key Laboratory of Agro-Products Quality and Safety of Chinese Ministry of Agriculture, Beijing 100081, P. R. China. Electronic address: 13522807385@163.com.Institute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Science/Key Laboratory of Agro-Products Quality and Safety of Chinese Ministry of Agriculture, Beijing 100081, P. R. China.Institute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Science/Key Laboratory of Agro-Products Quality and Safety of Chinese Ministry of Agriculture, Beijing 100081, P. R. China. Electronic address: sheyongxin@caas.cn.State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology, Shandong Academy of Sciences, Jinan, 250353, China; Department of Pharmacology, Faculty of Veterinary Medicine, Cairo University, 12211-Giza, Egypt; Department of Medical Pharmacology, Medical Faculty, Ataturk University, 25240-Erzurum, Turkey. Electronic address: abdelaty44@hotmail.com.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

33957346

Citation

Feng, Gege, et al. "Preparation of Molecularly Imprinted Polymer With Class-specific Recognition for Determination of 29 Sulfonylurea Herbicides in Agro-products." Journal of Chromatography. A, vol. 1647, 2021, p. 462143.
Feng G, Sun J, Wang M, et al. Preparation of molecularly imprinted polymer with class-specific recognition for determination of 29 sulfonylurea herbicides in agro-products. J Chromatogr A. 2021;1647:462143.
Feng, G., Sun, J., Wang, M., Wang, M., Li, Z., Wang, S., Zheng, L., Wang, J., She, Y., & Abd El-Aty, A. M. (2021). Preparation of molecularly imprinted polymer with class-specific recognition for determination of 29 sulfonylurea herbicides in agro-products. Journal of Chromatography. A, 1647, 462143. https://doi.org/10.1016/j.chroma.2021.462143
Feng G, et al. Preparation of Molecularly Imprinted Polymer With Class-specific Recognition for Determination of 29 Sulfonylurea Herbicides in Agro-products. J Chromatogr A. 2021 Jun 21;1647:462143. PubMed PMID: 33957346.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Preparation of molecularly imprinted polymer with class-specific recognition for determination of 29 sulfonylurea herbicides in agro-products. AU - Feng,Gege, AU - Sun,Jianchun, AU - Wang,Miao, AU - Wang,Mengqiang, AU - Li,Zhuang, AU - Wang,Shanshan, AU - Zheng,Lufei, AU - Wang,Jing, AU - She,Yongxin, AU - Abd El-Aty,A M, Y1 - 2021/04/09/ PY - 2021/01/16/received PY - 2021/03/29/revised PY - 2021/04/06/accepted PY - 2021/5/7/pubmed PY - 2021/5/21/medline PY - 2021/5/6/entrez KW - Agro-products KW - LC-MS/MS KW - Molecularly imprinted polymer KW - Residue detection KW - Solid-phase extraction KW - Sulfonylurea herbicides SP - 462143 EP - 462143 JF - Journal of chromatography. A JO - J Chromatogr A VL - 1647 N2 - Molecularly imprinting polymers with high selectivity toward 29 sulfonylurea herbicides were synthesized by precipitation polymerization, using metsulfuron-methyl and chlorsulfuron as the template molecule, 4-vinylpyridine as the function monomer, divinylbenzene as the crosslinking agent, and acetonitrile as porogen. The imprinted polymers were characterized and measured by scanning electron microscopy (SEM) and equilibrium adsorption experiments. The molecularly imprinted polymers displayed specific recognition for the tested 29 sulfonylurea herbicides, and the maximum apparent binding capacity was found to be 18.81 mg/g. The synthesized polymer was used as a solid-phase extraction (SPE) column coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) for determination of the tested analytes in agro-products. Within the range of 2-100 μg/L, the tested analytes have achieved a good linear association with correlation coefficient (R2) > 0.999. The calculated limits of detection (LODs, S/N=3) as along with limits of quantification (LOQs, S/N=10) were in the ranges of 0.005-0.07 μg/L and 0.018-0.23 μg/L, respectively. Under different spiking levels, the recovery rates were ranged from 74.8% - 110.5%, and the relative standard deviation (RSDs) were < 5.3%. Finally, the feasibility of the proposed methodology was successfully applied for detection of sulfonylurea herbicides in crops, vegetables, and oils samples. SN - 1873-3778 UR - https://www.unboundmedicine.com/medline/citation/33957346/Preparation_of_molecularly_imprinted_polymer_with_class_specific_recognition_for_determination_of_29_sulfonylurea_herbicides_in_agro_products_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0021-9673(21)00267-3 DB - PRIME DP - Unbound Medicine ER -