TY - JOUR T1 - Acceptance of a COVID-19 vaccine and associated factors among pregnant women in China: a multi-center cross-sectional study based on health belief model. AU - Tao,Liyuan, AU - Wang,Ruitong, AU - Han,Na, AU - Liu,Jihong, AU - Yuan,Chuanxiang, AU - Deng,Lixia, AU - Han,Chunhua, AU - Sun,Fenglan, AU - Liu,Min, AU - Liu,Jue, Y1 - 2021/05/14/ PY - 2021/5/15/pubmed PY - 2021/9/30/medline PY - 2021/5/14/entrez KW - COVID-19 KW - acceptance KW - pregnant women KW - vaccine KW - vaccine hesitancy SP - 2378 EP - 2388 JF - Human vaccines & immunotherapeutics JO - Hum Vaccin Immunother VL - 17 IS - 8 N2 - Background: Vaccine hesitancy has been recognized as an urgent public health issue. We aimed to explore the acceptance of a COVID-19 vaccine and related factors among pregnant women, a vulnerable population for vaccine-preventable diseases.Methods: A multi-center cross-sectional study among pregnant women was conducted in five provinces of mainland China from November 13 to 27, 2020. We collected sociodemographic characteristics, attitude, knowledge, and health beliefs on COVID-19 vaccination. Locally weighted scatterplot smoothing regression analysis was used to assess the trends of vaccination acceptance. Multivariable logistic regression was performed to identify factors related to vaccination acceptance.Results: Among the 1392 pregnant women, the acceptance rate of a COVID-19 vaccine were 77.4% (95%CI 75.1-79.5%). In the multivariable regression model, the acceptance rate was associated with young age (aOR = 1.87, 95% CI: 1.20-2.93), western region (aOR = 2.73, 95% CI: 1.72-4.32), low level of education (aOR = 2.49, 95% CI: 1.13-5.51), late pregnancy (aOR = 1.49, 95% CI: 1.03-2.16), high knowledge score on COVID-19 (aOR = 1.05, 95% CI: 1.01-1.10), high level of perceived susceptibility (aOR = 2.18, 95% CI: 1.36-3.49), low level of perceived barriers (aOR = 4.76, 95% CI: 2.23-10.18), high level of perceived benefit (aOR = 2.18, 95% CI: 1.36-3.49), and high level of perceived cues to action (aOR = 15.70, 95% CI: 8.28-29.80).Conclusions: About one quarters of pregnant women have vaccine hesitancy. Our findings highlight that targeted and multipronged efforts are needed to build vaccine literacy and confidence to increase the acceptance of a COVID-19 vaccine during the COVID-19 pandemic, especially for vulnerable populations. SN - 2164-554X UR - https://www.unboundmedicine.com/medline/citation/33989109/Acceptance_of_a_COVID_19_vaccine_and_associated_factors_among_pregnant_women_in_China:_a_multi_center_cross_sectional_study_based_on_health_belief_model_ DB - PRIME DP - Unbound Medicine ER -