Higher Morbidity and Mortality in Trauma Intensive Care Unit Patients with Opium Addiction.
Addict Health. 2021 Jan; 13(1):1-8.AH

Abstract

BACKGROUND

Opium addiction is associated with multiple physical, psychological, and social problems. The aim of this study was to compare the risk of morbidity and mortality in opium-addicted and non-addicted trauma patients admitted to the intensive care units (ICUs) of trauma center of Kerman Province, Iran.

METHODS

In this cohort study, a total of 200 addict and non-addicted patients who were admitted due to trauma in ICUs of Shahid Bahonar Hospital in Kerman during 9 months of 2018 were included. Patients were compared in terms of mortality, incidence of pressure ulcers, incidence of organ failure, duration of mechanical ventilation, and duration of hospitalization. Data were analysed using Fisher's exact test and independent t-test at P < 0.05.

FINDINGS

Out of 197 examined patients, 161 (81.7%) individuals were men and 36 (18.3%) were women. Moreover, 98 (49.7%) patients had a history of opium abuse, while 99 (50.2%) patients had no history of opium addiction. The addicted and non-addicted groups had no significant differences in terms of age (P = 0.650) and gender (P = 0.580). In addicted patients, mortality, duration of mechanical ventilation (P = 0.027), the incidence of pressure ulcer, and organ failure were significantly higher (P < 0.001), but mean ICU stay and hospitalization time was the same in both groups.

CONCLUSION

The results of this study indicated higher mortality and morbidity in opium-addicted patients admitted to ICU than non-addicted ones. This suggests that various systems of the body are affected by opium and, in certain circumstances such as severe diseases, this will cause problems for patients. Therefore, experts should pay attention to complications and side effects of addiction in the management of critical patients with a history of opium abuse.

Links

PMC Free PDF

Authors+Show Affiliations

Ahmadinejad M

Neuroscience Research Center, Institute of Nuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.

Karimi-Aliabadi H

Neuroscience Research Center, Institute of Nuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.

Dehghan M

Nursing Research Center, Kerman University of Medical Sciences, Kerman, Iran.

Mangolian P

Nursing Research Center, Kerman University of Medical Sciences, Kerman, Iran.

Tajoddini S

Department of Emergency Medicine, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

33995954

Citation

Ahmadinejad, Mehdi, et al. "Higher Morbidity and Mortality in Trauma Intensive Care Unit Patients With Opium Addiction." Addiction & Health, vol. 13, no. 1, 2021, pp. 1-8.

Ahmadinejad M, Karimi-Aliabadi H, Dehghan M, et al. Higher Morbidity and Mortality in Trauma Intensive Care Unit Patients with Opium Addiction. Addict Health. 2021;13(1):1-8.

Ahmadinejad, M., Karimi-Aliabadi, H., Dehghan, M., Mangolian, P., & Tajoddini, S. (2021). Higher Morbidity and Mortality in Trauma Intensive Care Unit Patients with Opium Addiction. Addiction & Health, 13(1), 1-8. https://doi.org/10.22122/ahj.v13i1.284

Ahmadinejad M, et al. Higher Morbidity and Mortality in Trauma Intensive Care Unit Patients With Opium Addiction. Addict Health. 2021;13(1):1-8. PubMed PMID: 33995954.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - Higher Morbidity and Mortality in Trauma Intensive Care Unit Patients with Opium Addiction. AU - Ahmadinejad,Mehdi, AU - Karimi-Aliabadi,Hakimeh, AU - Dehghan,Mahlagha, AU - Mangolian,Parvin, AU - Tajoddini,Shahrad, PY - 2021/5/17/entrez PY - 2021/5/18/pubmed PY - 2021/5/18/medline KW - Intensive care units KW - Morbidity KW - Mortality KW - Opioid-related disorders SP - 1 EP - 8 JF - Addiction & health JO - Addict Health VL - 13 IS - 1 N2 - BACKGROUND: Opium addiction is associated with multiple physical, psychological, and social problems. The aim of this study was to compare the risk of morbidity and mortality in opium-addicted and non-addicted trauma patients admitted to the intensive care units (ICUs) of trauma center of Kerman Province, Iran. METHODS: In this cohort study, a total of 200 addict and non-addicted patients who were admitted due to trauma in ICUs of Shahid Bahonar Hospital in Kerman during 9 months of 2018 were included. Patients were compared in terms of mortality, incidence of pressure ulcers, incidence of organ failure, duration of mechanical ventilation, and duration of hospitalization. Data were analysed using Fisher's exact test and independent t-test at P < 0.05. FINDINGS: Out of 197 examined patients, 161 (81.7%) individuals were men and 36 (18.3%) were women. Moreover, 98 (49.7%) patients had a history of opium abuse, while 99 (50.2%) patients had no history of opium addiction. The addicted and non-addicted groups had no significant differences in terms of age (P = 0.650) and gender (P = 0.580). In addicted patients, mortality, duration of mechanical ventilation (P = 0.027), the incidence of pressure ulcer, and organ failure were significantly higher (P < 0.001), but mean ICU stay and hospitalization time was the same in both groups. CONCLUSION: The results of this study indicated higher mortality and morbidity in opium-addicted patients admitted to ICU than non-addicted ones. This suggests that various systems of the body are affected by opium and, in certain circumstances such as severe diseases, this will cause problems for patients. Therefore, experts should pay attention to complications and side effects of addiction in the management of critical patients with a history of opium abuse. SN - 2008-4633 UR - https://www.unboundmedicine.com/medline/citation/33995954/Higher_Morbidity_and_Mortality_in_Trauma_Intensive_Care_Unit_Patients_with_Opium_Addiction_ DB - PRIME DP - Unbound Medicine ER -

Tags

Higher Morbidity and Mortality in Trauma Intensive Care Unit Patients with Opium Addiction.Addict Health. 2021 Jan; 13(1):1-8.AH