Tags

Type your tag names separated by a space and hit enter

Genome-Wide Association Analysis and Genomic Prediction for Adult-Plant Resistance to Septoria Tritici Blotch and Powdery Mildew in Winter Wheat.
Front Genet. 2021; 12:661742.FG

Abstract

Septoria tritici blotch (STB) caused by the fungal pathogen Zymoseptoria tritici and powdery mildew (PM) caused by Blumeria graminis f.sp tritici (Bgt) are among the forefront foliar diseases of wheat that lead to a significant loss of grain yield and quality. Resistance breeding aimed at developing varieties with inherent resistance to STB and PM diseases has been the most sustainable and environment-friendly approach. In this study, 175 winter wheat landraces and historical cultivars originated from the Nordic region were evaluated for adult-plant resistance (APR) to STB and PM in Denmark, Estonia, Lithuania, and Sweden. Genome-wide association study (GWAS) and genomic prediction (GP) were performed based on the adult-plant response to STB and PM in field conditions using 7,401 single-nucleotide polymorphism (SNP) markers generated by 20K SNP chip. Genotype-by-environment interaction was significant for both disease scores. GWAS detected stable and environment-specific quantitative trait locis (QTLs) on chromosomes 1A, 1B, 1D, 2B, 3B, 4A, 5A, 6A, and 6B for STB and 2A, 2D, 3A, 4B, 5A, 6B, 7A, and 7B for PM adult-plant disease resistance. GP accuracy was improved when assisted with QTL from GWAS as a fixed effect. The GWAS-assisted GP accuracy ranged within 0.53-0.75 and 0.36-0.83 for STB and PM, respectively, across the tested environments. This study highlights that landraces and historical cultivars are a valuable source of APR to STB and PM. Such germplasm could be used to identify and introgress novel resistance genes to modern breeding lines.

Authors+Show Affiliations

Department of Plant Breeding, Swedish University of Agricultural Sciences, Alnarp, Sweden.Institute of Agriculture, Lithuanian Research Centre for Agriculture and Forestry (LAMMC), Kėdainiai, Lithuania.Department of Plant Breeding, Swedish University of Agricultural Sciences, Alnarp, Sweden.Lantmännen Lantbruk, Svalöv, Sweden.Estonian Crop Research Institute, Jõgeva, Estonia.Department of Agroecology, Aarhus University, Slagelse, Denmark.Estonian University of Life Sciences, Tartu, Estonia.Estonian Crop Research Institute, Jõgeva, Estonia.Institute of Agriculture, Lithuanian Research Centre for Agriculture and Forestry (LAMMC), Kėdainiai, Lithuania.Nordic Genetic Resource Center, Alnarp, Sweden.Department of Plant Breeding, Swedish University of Agricultural Sciences, Alnarp, Sweden.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

34054924

Citation

Alemu, Admas, et al. "Genome-Wide Association Analysis and Genomic Prediction for Adult-Plant Resistance to Septoria Tritici Blotch and Powdery Mildew in Winter Wheat." Frontiers in Genetics, vol. 12, 2021, p. 661742.
Alemu A, Brazauskas G, Gaikpa DS, et al. Genome-Wide Association Analysis and Genomic Prediction for Adult-Plant Resistance to Septoria Tritici Blotch and Powdery Mildew in Winter Wheat. Front Genet. 2021;12:661742.
Alemu, A., Brazauskas, G., Gaikpa, D. S., Henriksson, T., Islamov, B., Jørgensen, L. N., Koppel, M., Koppel, R., Liatukas, Ž., Svensson, J. T., & Chawade, A. (2021). Genome-Wide Association Analysis and Genomic Prediction for Adult-Plant Resistance to Septoria Tritici Blotch and Powdery Mildew in Winter Wheat. Frontiers in Genetics, 12, 661742. https://doi.org/10.3389/fgene.2021.661742
Alemu A, et al. Genome-Wide Association Analysis and Genomic Prediction for Adult-Plant Resistance to Septoria Tritici Blotch and Powdery Mildew in Winter Wheat. Front Genet. 2021;12:661742. PubMed PMID: 34054924.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Genome-Wide Association Analysis and Genomic Prediction for Adult-Plant Resistance to Septoria Tritici Blotch and Powdery Mildew in Winter Wheat. AU - Alemu,Admas, AU - Brazauskas,Gintaras, AU - Gaikpa,David S, AU - Henriksson,Tina, AU - Islamov,Bulat, AU - Jørgensen,Lise Nistrup, AU - Koppel,Mati, AU - Koppel,Reine, AU - Liatukas,Žilvinas, AU - Svensson,Jan T, AU - Chawade,Aakash, Y1 - 2021/05/12/ PY - 2021/01/31/received PY - 2021/04/06/accepted PY - 2021/5/31/entrez PY - 2021/6/1/pubmed PY - 2021/6/1/medline KW - GWAS KW - Septoria tritici blotch KW - genebank KW - genomic prediction KW - powdery mildew KW - wheat SP - 661742 EP - 661742 JF - Frontiers in genetics JO - Front Genet VL - 12 N2 - Septoria tritici blotch (STB) caused by the fungal pathogen Zymoseptoria tritici and powdery mildew (PM) caused by Blumeria graminis f.sp tritici (Bgt) are among the forefront foliar diseases of wheat that lead to a significant loss of grain yield and quality. Resistance breeding aimed at developing varieties with inherent resistance to STB and PM diseases has been the most sustainable and environment-friendly approach. In this study, 175 winter wheat landraces and historical cultivars originated from the Nordic region were evaluated for adult-plant resistance (APR) to STB and PM in Denmark, Estonia, Lithuania, and Sweden. Genome-wide association study (GWAS) and genomic prediction (GP) were performed based on the adult-plant response to STB and PM in field conditions using 7,401 single-nucleotide polymorphism (SNP) markers generated by 20K SNP chip. Genotype-by-environment interaction was significant for both disease scores. GWAS detected stable and environment-specific quantitative trait locis (QTLs) on chromosomes 1A, 1B, 1D, 2B, 3B, 4A, 5A, 6A, and 6B for STB and 2A, 2D, 3A, 4B, 5A, 6B, 7A, and 7B for PM adult-plant disease resistance. GP accuracy was improved when assisted with QTL from GWAS as a fixed effect. The GWAS-assisted GP accuracy ranged within 0.53-0.75 and 0.36-0.83 for STB and PM, respectively, across the tested environments. This study highlights that landraces and historical cultivars are a valuable source of APR to STB and PM. Such germplasm could be used to identify and introgress novel resistance genes to modern breeding lines. SN - 1664-8021 UR - https://www.unboundmedicine.com/medline/citation/34054924/Genome_Wide_Association_Analysis_and_Genomic_Prediction_for_Adult_Plant_Resistance_to_Septoria_Tritici_Blotch_and_Powdery_Mildew_in_Winter_Wheat_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/34054924/ DB - PRIME DP - Unbound Medicine ER -