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Hospitalization of Adolescents Aged 12-17 Years with Laboratory-Confirmed COVID-19 - COVID-NET, 14 States, March 1, 2020-April 24, 2021.
MMWR Morb Mortal Wkly Rep. 2021 Jun 11; 70(23):851-857.MM

Abstract

Most COVID-19-associated hospitalizations occur in older adults, but severe disease that requires hospitalization occurs in all age groups, including adolescents aged 12-17 years (1). On May 10, 2021, the Food and Drug Administration expanded the Emergency Use Authorization for Pfizer-BioNTech COVID-19 vaccine to include persons aged 12-15 years, and CDC's Advisory Committee on Immunization Practices recommended it for this age group on May 12, 2021.* Before that time, COVID-19 vaccines had been available only to persons aged ≥16 years. Understanding and describing the epidemiology of COVID-19-associated hospitalizations in adolescents and comparing it with adolescent hospitalizations associated with other vaccine-preventable respiratory viruses, such as influenza, offers evidence of the benefits of expanding the recommended age range for vaccination and provides a baseline and context from which to assess vaccination impact. Using the Coronavirus Disease 2019-Associated Hospitalization Surveillance Network (COVID-NET), CDC examined COVID-19-associated hospitalizations among adolescents aged 12-17 years, including demographic and clinical characteristics of adolescents admitted during January 1-March 31, 2021, and hospitalization rates (hospitalizations per 100,000 persons) among adolescents during March 1, 2020-April 24, 2021. Among 204 adolescents who were likely hospitalized primarily for COVID-19 during January 1-March 31, 2021, 31.4% were admitted to an intensive care unit (ICU), and 4.9% required invasive mechanical ventilation; there were no associated deaths. During March 1, 2020-April 24, 2021, weekly adolescent hospitalization rates peaked at 2.1 per 100,000 in early January 2021, declined to 0.6 in mid-March, and then rose to 1.3 in April. Cumulative COVID-19-associated hospitalization rates during October 1, 2020-April 24, 2021, were 2.5-3.0 times higher than were influenza-associated hospitalization rates from three recent influenza seasons (2017-18, 2018-19, and 2019-20) obtained from the Influenza Hospitalization Surveillance Network (FluSurv-NET). Recent increased COVID-19-associated hospitalization rates in March and April 2021 and the potential for severe disease in adolescents reinforce the importance of continued COVID-19 prevention measures, including vaccination and correct and consistent wearing of masks by persons not yet fully vaccinated or when required by laws, rules, or regulations.†.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

34111061

Citation

Havers, Fiona P., et al. "Hospitalization of Adolescents Aged 12-17 Years With Laboratory-Confirmed COVID-19 - COVID-NET, 14 States, March 1, 2020-April 24, 2021." MMWR. Morbidity and Mortality Weekly Report, vol. 70, no. 23, 2021, pp. 851-857.
Havers FP, Whitaker M, Self JL, et al. Hospitalization of Adolescents Aged 12-17 Years with Laboratory-Confirmed COVID-19 - COVID-NET, 14 States, March 1, 2020-April 24, 2021. MMWR Morb Mortal Wkly Rep. 2021;70(23):851-857.
Havers, F. P., Whitaker, M., Self, J. L., Chai, S. J., Kirley, P. D., Alden, N. B., Kawasaki, B., Meek, J., Yousey-Hindes, K., Anderson, E. J., Openo, K. P., Weigel, A., Teno, K., Monroe, M. L., Ryan, P. A., Reeg, L., Kohrman, A., Lynfield, R., Como-Sabetti, K., ... Taylor, C. A. (2021). Hospitalization of Adolescents Aged 12-17 Years with Laboratory-Confirmed COVID-19 - COVID-NET, 14 States, March 1, 2020-April 24, 2021. MMWR. Morbidity and Mortality Weekly Report, 70(23), 851-857. https://doi.org/10.15585/mmwr.mm7023e1
Havers FP, et al. Hospitalization of Adolescents Aged 12-17 Years With Laboratory-Confirmed COVID-19 - COVID-NET, 14 States, March 1, 2020-April 24, 2021. MMWR Morb Mortal Wkly Rep. 2021 Jun 11;70(23):851-857. PubMed PMID: 34111061.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hospitalization of Adolescents Aged 12-17 Years with Laboratory-Confirmed COVID-19 - COVID-NET, 14 States, March 1, 2020-April 24, 2021. AU - Havers,Fiona P, AU - Whitaker,Michael, AU - Self,Julie L, AU - Chai,Shua J, AU - Kirley,Pam Daily, AU - Alden,Nisha B, AU - Kawasaki,Breanna, AU - Meek,James, AU - Yousey-Hindes,Kimberly, AU - Anderson,Evan J, AU - Openo,Kyle P, AU - Weigel,Andrew, AU - Teno,Kenzie, AU - Monroe,Maya L, AU - Ryan,Patricia A, AU - Reeg,Libby, AU - Kohrman,Alexander, AU - Lynfield,Ruth, AU - Como-Sabetti,Kathryn, AU - Poblete,Mayvilynne, AU - McMullen,Chelsea, AU - Muse,Alison, AU - Spina,Nancy, AU - Bennett,Nancy M, AU - Gaitán,Maria, AU - Billing,Laurie M, AU - Shiltz,Jess, AU - Sutton,Melissa, AU - Abdullah,Nasreen, AU - Schaffner,William, AU - Talbot,H Keipp, AU - Crossland,Melanie, AU - George,Andrea, AU - Patel,Kadam, AU - Pham,Huong, AU - Milucky,Jennifer, AU - Anglin,Onika, AU - Ujamaa,Dawud, AU - Hall,Aron J, AU - Garg,Shikha, AU - Taylor,Christopher A, AU - ,, Y1 - 2021/06/11/ PY - 2021/6/10/entrez PY - 2021/6/11/pubmed PY - 2021/6/12/medline SP - 851 EP - 857 JF - MMWR. Morbidity and mortality weekly report JO - MMWR Morb Mortal Wkly Rep VL - 70 IS - 23 N2 - Most COVID-19-associated hospitalizations occur in older adults, but severe disease that requires hospitalization occurs in all age groups, including adolescents aged 12-17 years (1). On May 10, 2021, the Food and Drug Administration expanded the Emergency Use Authorization for Pfizer-BioNTech COVID-19 vaccine to include persons aged 12-15 years, and CDC's Advisory Committee on Immunization Practices recommended it for this age group on May 12, 2021.* Before that time, COVID-19 vaccines had been available only to persons aged ≥16 years. Understanding and describing the epidemiology of COVID-19-associated hospitalizations in adolescents and comparing it with adolescent hospitalizations associated with other vaccine-preventable respiratory viruses, such as influenza, offers evidence of the benefits of expanding the recommended age range for vaccination and provides a baseline and context from which to assess vaccination impact. Using the Coronavirus Disease 2019-Associated Hospitalization Surveillance Network (COVID-NET), CDC examined COVID-19-associated hospitalizations among adolescents aged 12-17 years, including demographic and clinical characteristics of adolescents admitted during January 1-March 31, 2021, and hospitalization rates (hospitalizations per 100,000 persons) among adolescents during March 1, 2020-April 24, 2021. Among 204 adolescents who were likely hospitalized primarily for COVID-19 during January 1-March 31, 2021, 31.4% were admitted to an intensive care unit (ICU), and 4.9% required invasive mechanical ventilation; there were no associated deaths. During March 1, 2020-April 24, 2021, weekly adolescent hospitalization rates peaked at 2.1 per 100,000 in early January 2021, declined to 0.6 in mid-March, and then rose to 1.3 in April. Cumulative COVID-19-associated hospitalization rates during October 1, 2020-April 24, 2021, were 2.5-3.0 times higher than were influenza-associated hospitalization rates from three recent influenza seasons (2017-18, 2018-19, and 2019-20) obtained from the Influenza Hospitalization Surveillance Network (FluSurv-NET). Recent increased COVID-19-associated hospitalization rates in March and April 2021 and the potential for severe disease in adolescents reinforce the importance of continued COVID-19 prevention measures, including vaccination and correct and consistent wearing of masks by persons not yet fully vaccinated or when required by laws, rules, or regulations.†. SN - 1545-861X UR - https://www.unboundmedicine.com/medline/citation/34111061/Hospitalization_of_Adolescents_Aged_12-17_Years_with_Laboratory-Confirmed_COVID-19_-_COVID-NET,_14_States,_March_1,_2020-April_24,_2021. L2 - https://doi.org/10.15585/mmwr.mm7023e1 DB - PRIME DP - Unbound Medicine ER -