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Accelerating towards human African trypanosomiasis elimination: Issues and opportunities.
J Vector Borne Dis. 2020 Apr-Jun; 57(2):105-113.JV

Abstract

Human African trypanosomiasis (HAT) has been an alarming global public health issue. The disease affects mainly poor and marginalized people in low-resource settings and is caused by two subspecies of haemoflagellate parasite, Trypanosoma brucei and transmitted by tsetse flies. Progress made in HAT control during the past decade has prompted increasing global dialogue on its elimination and eradication. The disease is targeted by the World Health Organization (WHO) for elimination as a public health problem by 2020 and to terminate its transmission globally by 2030, along-side other Neglected Tropical Diseases (NTD). Several methods have been used to control tsetse flies and the disease transmitted by them. Old and new tools to control the disease are available with constraints. Currently, there are no vaccines available. Efforts towards intervention to control the disease over the past decade have seen considerable progress and remarkable success with incidence dropping progressively, reversing the upward trend of reported cases. This gives credence in a real progress in its elimination. This study reviews various control measures, progress and a highlight of control issues, vector and parasite barriers that may have been hindering progress towards its elimination.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Ozioko KU
Department of Zoology and Environmental Biology, University of Nigeria, Nsukka, Nigeria.
Okoye CI
Department of Zoology and Environmental Biology, University of Nigeria, Nsukka, Nigeria.
Obiezue RN
Department of Zoology and Environmental Biology, University of Nigeria, Nsukka, Nigeria.
Idika IK
Department of Veterinary Parasitology and Entomology, University of Nigeria, Nsukka, Nigeria.
Awudu RA
Central Laboratory Unit, Federal University Wukari, Wukari, Taraba State, Nigeria.
Ezewudo BI
Department of Zoology, Nnamdi Azikiwe University, Akwa Anambra State, Nigeria.
Ezea CO
Department of Biology, Federal University of Technology, Owerre, Imo State, Nigeria.

MeSH

AnimalsDisease EradicationGlobal HealthHumansInsect ControlInsect VectorsTrypanosomiasis, AfricanTsetse FliesWorld Health Organization

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

34290154

Citation

Ozioko, Kingsley Uchenna, et al. "Accelerating Towards Human African Trypanosomiasis Elimination: Issues and Opportunities." Journal of Vector Borne Diseases, vol. 57, no. 2, 2020, pp. 105-113.
Ozioko KU, Okoye CI, Obiezue RN, et al. Accelerating towards human African trypanosomiasis elimination: Issues and opportunities. J Vector Borne Dis. 2020;57(2):105-113.
Ozioko, K. U., Okoye, C. I., Obiezue, R. N., Idika, I. K., Awudu, R. A., Ezewudo, B. I., & Ezea, C. O. (2020). Accelerating towards human African trypanosomiasis elimination: Issues and opportunities. Journal of Vector Borne Diseases, 57(2), 105-113. https://doi.org/10.4103/0972-9062.310860
Ozioko KU, et al. Accelerating Towards Human African Trypanosomiasis Elimination: Issues and Opportunities. J Vector Borne Dis. 2020 Apr-Jun;57(2):105-113. PubMed PMID: 34290154.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Accelerating towards human African trypanosomiasis elimination: Issues and opportunities. AU - Ozioko,Kingsley Uchenna, AU - Okoye,Chris Ikem, AU - Obiezue,Rose Nduka, AU - Idika,Idika Kalu, AU - Awudu,Raymond Agbu, AU - Ezewudo,Bede Izuchukwu, AU - Ezea,Celestine Osita, PY - 2021/7/22/entrez PY - 2020/4/1/pubmed PY - 2021/11/23/medline KW - Elimination KW - Human African trypanosomiasis KW - Issues KW - Opportunities SP - 105 EP - 113 JF - Journal of vector borne diseases JO - J Vector Borne Dis VL - 57 IS - 2 N2 - Human African trypanosomiasis (HAT) has been an alarming global public health issue. The disease affects mainly poor and marginalized people in low-resource settings and is caused by two subspecies of haemoflagellate parasite, Trypanosoma brucei and transmitted by tsetse flies. Progress made in HAT control during the past decade has prompted increasing global dialogue on its elimination and eradication. The disease is targeted by the World Health Organization (WHO) for elimination as a public health problem by 2020 and to terminate its transmission globally by 2030, along-side other Neglected Tropical Diseases (NTD). Several methods have been used to control tsetse flies and the disease transmitted by them. Old and new tools to control the disease are available with constraints. Currently, there are no vaccines available. Efforts towards intervention to control the disease over the past decade have seen considerable progress and remarkable success with incidence dropping progressively, reversing the upward trend of reported cases. This gives credence in a real progress in its elimination. This study reviews various control measures, progress and a highlight of control issues, vector and parasite barriers that may have been hindering progress towards its elimination. SN - 0972-9062 UR - https://www.unboundmedicine.com/medline/citation/34290154/Accelerating_towards_human_African_trypanosomiasis_elimination:_Issues_and_opportunities_ DB - PRIME DP - Unbound Medicine ER -