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An observational study of a cohort of citizens receiving the AZD1222 vaccine against SARS-CoV-2.
Future Sci OA. 2021 Sep; 7(8):FSO739.FS

Abstract

In this retrospective study, a cohort of 67 subjects vaccinated with AZD1222 was retrospectively observed. Consistently with published findings, no serious adverse event was reported, and all adverse events reported (fever, muscle ache and/or pain in the site of injection) had resolved by day 8. Of note, some citizens were prescribed low-dose aspirin and even heparin for thrombosis prevention. We also found variations in laboratory test results (full blood count and chemistry) on day 1 compared with day 8. Physicians should be aware that no prevention therapy for thrombosis is currently recommended, given the very low incidence of this side effect. Additional studies are warranted to interpret our findings.

Authors+Show Affiliations

Centro di Referenza Nazionale per l'Analisi e Studio di Correlazione tra Ambiente, Animale e Uomo, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Portici, 80055, Italy.Centro di Referenza Nazionale per l'Analisi e Studio di Correlazione tra Ambiente, Animale e Uomo, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Portici, 80055, Italy. Dipartimento di Medicina Sperimentale, Università degli studi della Campania 'L Vanvitelli', Naples, 80138, Italy.Centro di Referenza Nazionale per l'Analisi e Studio di Correlazione tra Ambiente, Animale e Uomo, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Portici, 80055, Italy. Department of Medicine, Surgery & Dentistry (Scuola Medica Salernitana), University of Salerno, Baronissi, 84081, Italy.Centro di Referenza Nazionale per l'Analisi e Studio di Correlazione tra Ambiente, Animale e Uomo, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Portici, 80055, Italy.Department of Public Health, University of Naples 'Federico II', Naples, 80131, Italy.Centro di Referenza Nazionale per l'Analisi e Studio di Correlazione tra Ambiente, Animale e Uomo, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Portici, 80055, Italy.Centro di Referenza Nazionale per l'Analisi e Studio di Correlazione tra Ambiente, Animale e Uomo, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Portici, 80055, Italy.Centro di Referenza Nazionale per l'Analisi e Studio di Correlazione tra Ambiente, Animale e Uomo, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Portici, 80055, Italy.ASL Napoli 3 SUD, Torre del Greco, 80059, Italy.ASL Napoli 3 SUD, Torre del Greco, 80059, Italy.Cotugno Hospital, AORN Ospedali dei Colli, Naples, 80131, Italy.Cotugno Hospital, AORN Ospedali dei Colli, Naples, 80131, Italy.Cotugno Hospital, AORN Ospedali dei Colli, Naples, 80131, Italy.Cotugno Hospital, AORN Ospedali dei Colli, Naples, 80131, Italy.Cotugno Hospital, AORN Ospedali dei Colli, Naples, 80131, Italy.Cotugno Hospital, AORN Ospedali dei Colli, Naples, 80131, Italy.Food Safety, Nutrition & Veterinary Public Health Department, Istituto Superiore di Sanità, Rome, 00161, Italy.Centro di Referenza Nazionale per l'Analisi e Studio di Correlazione tra Ambiente, Animale e Uomo, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Portici, 80055, Italy.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

34290884

Citation

Cerino, Pellegrino, et al. "An Observational Study of a Cohort of Citizens Receiving the AZD1222 Vaccine Against SARS-CoV-2." Future Science OA, vol. 7, no. 8, 2021, pp. FSO739.
Cerino P, Coppola A, Pierri B, et al. An observational study of a cohort of citizens receiving the AZD1222 vaccine against SARS-CoV-2. Future Sci OA. 2021;7(8):FSO739.
Cerino, P., Coppola, A., Pierri, B., Volzone, P., Bruzzese, D., Pierri, A., Ferro, A., Schiavi, D., Coppola, A., Miniero, S., Atripaldi, L., Pirozzi, C., Rusciano, P., Macri, A., Boenzi, R., Sale, S., Brambilla, G., & Buonerba, C. (2021). An observational study of a cohort of citizens receiving the AZD1222 vaccine against SARS-CoV-2. Future Science OA, 7(8), FSO739. https://doi.org/10.2144/fsoa-2021-0064
Cerino P, et al. An Observational Study of a Cohort of Citizens Receiving the AZD1222 Vaccine Against SARS-CoV-2. Future Sci OA. 2021;7(8):FSO739. PubMed PMID: 34290884.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - An observational study of a cohort of citizens receiving the AZD1222 vaccine against SARS-CoV-2. AU - Cerino,Pellegrino, AU - Coppola,Annachiara, AU - Pierri,Biancamaria, AU - Volzone,Palmiero, AU - Bruzzese,Dario, AU - Pierri,Andrea, AU - Ferro,Amedeo, AU - Schiavi,Daniela, AU - Coppola,Antonio, AU - Miniero,Stefano, AU - Atripaldi,Luigi, AU - Pirozzi,Caterina, AU - Rusciano,Pasquale, AU - Macri,Alessandra, AU - Boenzi,Rita, AU - Sale,Silvia, AU - Brambilla,Gianfranco, AU - Buonerba,Carlo, Y1 - 2021/06/15/ PY - 2021/05/12/received PY - 2021/06/02/accepted PY - 2021/7/22/entrez PY - 2021/7/23/pubmed PY - 2021/7/23/medline KW - AZD1222 KW - COVID-19 KW - SARS-CoV-2 KW - adverse events KW - coagulation SP - FSO739 EP - FSO739 JF - Future science OA JO - Future Sci OA VL - 7 IS - 8 N2 - In this retrospective study, a cohort of 67 subjects vaccinated with AZD1222 was retrospectively observed. Consistently with published findings, no serious adverse event was reported, and all adverse events reported (fever, muscle ache and/or pain in the site of injection) had resolved by day 8. Of note, some citizens were prescribed low-dose aspirin and even heparin for thrombosis prevention. We also found variations in laboratory test results (full blood count and chemistry) on day 1 compared with day 8. Physicians should be aware that no prevention therapy for thrombosis is currently recommended, given the very low incidence of this side effect. Additional studies are warranted to interpret our findings. SN - 2056-5623 UR - https://www.unboundmedicine.com/medline/citation/34290884/An_observational_study_of_a_cohort_of_citizens_receiving_the_AZD1222_vaccine_against_SARS-CoV-2. L2 - https://doi.org/10.2144/fsoa-2021-0064 DB - PRIME DP - Unbound Medicine ER -
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