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Possible Vertical Transmission From an Unsuspected SARS-CoV-2-Infected Mother to Her Newborn.
Cureus. 2021 Jun; 13(6):e15717.C

Abstract

Although the Coronavirus Disease 2019 (COVID-19) has been found to have multiple routes of transmission, limited data exist on whether the vertical transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can occur from asymptomatic infected mothers to their newborns during pregnancy. We report a full-term newborn girl who was found to be positive for COVID-19 at 24 hours of life and subsequently symptomatic with fever, tachycardia, tachypnea, elevated lactate dehydrogenase, and elevated total bilirubin. The newborn was delivered by a mother who was not suspected of having COVID-19 before giving birth, but who developed fever and dyspnea five hours after delivery and was found to be positive for COVID-19. Upon further history collection, the mother reported recent mild nasal congestion in the days prior to delivery. This case highlights that the vertical transmission of COVID-19 to a newborn may occur late during the third trimester from a mother who was not suspected of having the infection. All pregnant women may need to be screened for COVID-19 symptoms, including non-specific symptoms, prior to admission for labor and delivery floors in order to perform diagnostic tests and recommended safety precautions to keep newborns and hospital personnel safe.

Authors+Show Affiliations

Pediatrics, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IRN. Pediatrics, Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IRN.Pediatrics, David Geffen School of Medicine, University of California, Los Angeles, USA.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

34290917

Citation

Naseh, Ali, and Sahar Ashrafzadeh. "Possible Vertical Transmission From an Unsuspected SARS-CoV-2-Infected Mother to Her Newborn." Cureus, vol. 13, no. 6, 2021, pp. e15717.
Naseh A, Ashrafzadeh S. Possible Vertical Transmission From an Unsuspected SARS-CoV-2-Infected Mother to Her Newborn. Cureus. 2021;13(6):e15717.
Naseh, A., & Ashrafzadeh, S. (2021). Possible Vertical Transmission From an Unsuspected SARS-CoV-2-Infected Mother to Her Newborn. Cureus, 13(6), e15717. https://doi.org/10.7759/cureus.15717
Naseh A, Ashrafzadeh S. Possible Vertical Transmission From an Unsuspected SARS-CoV-2-Infected Mother to Her Newborn. Cureus. 2021;13(6):e15717. PubMed PMID: 34290917.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Possible Vertical Transmission From an Unsuspected SARS-CoV-2-Infected Mother to Her Newborn. AU - Naseh,Ali, AU - Ashrafzadeh,Sahar, Y1 - 2021/06/17/ PY - 2021/06/17/accepted PY - 2021/7/22/entrez PY - 2021/7/23/pubmed PY - 2021/7/23/medline KW - asymptomatic KW - coronavirus infections KW - covid-19 KW - infant KW - maternal-infant infection KW - newborn health KW - pregnancy KW - sars-cov-2 KW - transplacental transmission KW - vertical infectious disease transmission SP - e15717 EP - e15717 JF - Cureus JO - Cureus VL - 13 IS - 6 N2 - Although the Coronavirus Disease 2019 (COVID-19) has been found to have multiple routes of transmission, limited data exist on whether the vertical transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can occur from asymptomatic infected mothers to their newborns during pregnancy. We report a full-term newborn girl who was found to be positive for COVID-19 at 24 hours of life and subsequently symptomatic with fever, tachycardia, tachypnea, elevated lactate dehydrogenase, and elevated total bilirubin. The newborn was delivered by a mother who was not suspected of having COVID-19 before giving birth, but who developed fever and dyspnea five hours after delivery and was found to be positive for COVID-19. Upon further history collection, the mother reported recent mild nasal congestion in the days prior to delivery. This case highlights that the vertical transmission of COVID-19 to a newborn may occur late during the third trimester from a mother who was not suspected of having the infection. All pregnant women may need to be screened for COVID-19 symptoms, including non-specific symptoms, prior to admission for labor and delivery floors in order to perform diagnostic tests and recommended safety precautions to keep newborns and hospital personnel safe. SN - 2168-8184 UR - https://www.unboundmedicine.com/medline/citation/34290917/Possible_Vertical_Transmission_From_an_Unsuspected_SARS-CoV-2-Infected_Mother_to_Her_Newborn. L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/34290917/ DB - PRIME DP - Unbound Medicine ER -
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