TY - JOUR T1 - Metastatic Vulval Crohn's Disease With Good Outcome on Ustekinumab. AU - Lim,Yizhe, AU - Singh,Manpreet, Y1 - 2021/07/08/ PY - 2021/07/08/accepted PY - 2021/8/10/entrez PY - 2021/8/11/pubmed PY - 2021/8/11/medline KW - crohn’s disease (cd) KW - cutaneous crohn’s disease KW - gastroenterology KW - gynaecology KW - metastatic crohn’s disease KW - ustekinumab KW - vulval KW - vulvar SP - e16252 EP - e16252 JF - Cureus JO - Cureus VL - 13 IS - 7 N2 - Vulval Crohn's disease is a rare manifestation of Crohn's disease. Although it is usually caused by a fistulating process, it may be a result of a metastatic disease process as well, the exact mechanisms of which are not well understood yet. Vulval Crohn's disease may occur before the onset of bowel symptoms and may continue to be active while bowel symptoms are quiescent. Coupled with the fact that most vulval Crohn's lesions are similar to other disease processes, it can prove to be a diagnostic challenge. Due to its rarity, no guidelines for treatment exist; however, most reports agree that when symptoms are not controlled with antibiotics and topical steroids, immunosuppressive medications such as oral steroids and biological agents are the way forward. Although surgery may be an option, data suggest that its use is scarce. We report the case of a 47-year-old Caucasian woman with bilateral metastatic vulval Crohn's disease from a district hospital in the United Kingdom who responded well to ustekinumab. This is one of the first few cases reporting good clinical outcomes with the agent. SN - 2168-8184 UR - https://www.unboundmedicine.com/medline/citation/34373813/Metastatic_Vulval_Crohn's_Disease_With_Good_Outcome_on_Ustekinumab_ DB - PRIME DP - Unbound Medicine ER -