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Comparative study of Amsel's criteria and Nugent scoring for diagnosis of bacterial vaginosis in a tertiary care hospital, Nepal.
BMC Infect Dis. 2021 Aug 17; 21(1):825.BI

Abstract

BACKGROUND

The most common pathological cause of abnormal vaginal discharge in reproductive-aged women is bacterial vaginosis (BV). Amsel's criteria and Nugent scoring systems are commonly employed approaches for the diagnosis of BV. Despite the Nugent scoring system being the gold standard method for diagnosing BV, Amsel's criteria are generally preferred in clinical setup owing to the fact Nugent scoring requires considerable time and expert microscopist. This study was conducted to determine the diagnostic value of Amsel's criteria by comparing it with the Nugent scoring system.

METHODS

This was a descriptive cross-sectional study conducted at Tribhuvan University Teaching Hospital, Nepal from October 2016 to September 2017. Vaginal specimens were collected from a total of 141 women presenting with abnormal vaginal discharge. The sensitivity, specificity, positive predictive value, and negative predictive value of Amsel's criteria were calculated, and each component of Amsel's criteria was compared to the Nugent scoring system.

RESULTS

The sensitivity, specificity, positive predictive value, and negative predictive value of Amsel's criteria were 50%, 98.2%, 87.5%, and 88.8% respectively. The clue cells showed 100% specificity and vaginal discharge with pH > 4.5 had 89.3% sensitivity while compared with Nugent's scoring system.

CONCLUSIONS

Amsel's criteria can be used as an adjunct method to Nugent scoring for the diagnosis of BV in the hands of skilled manpower in resources limited countries. The presence of clue cell and positive whiff test of Amsel's criteria shows good match with Nugent's score.

Authors+Show Affiliations

Department of Clinical Microbiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal. bhujelrajshree@iom.edu.np.Department of Clinical Microbiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.Department of Microbiology, Rajarshi Janak University, Janakpurdham, Nepal.Department of Obstetrics and Gynecology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.Department of Clinical Microbiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

34404367

Citation

Bhujel, Rajshree, et al. "Comparative Study of Amsel's Criteria and Nugent Scoring for Diagnosis of Bacterial Vaginosis in a Tertiary Care Hospital, Nepal." BMC Infectious Diseases, vol. 21, no. 1, 2021, p. 825.
Bhujel R, Mishra SK, Yadav SK, et al. Comparative study of Amsel's criteria and Nugent scoring for diagnosis of bacterial vaginosis in a tertiary care hospital, Nepal. BMC Infect Dis. 2021;21(1):825.
Bhujel, R., Mishra, S. K., Yadav, S. K., Bista, K. D., & Parajuli, K. (2021). Comparative study of Amsel's criteria and Nugent scoring for diagnosis of bacterial vaginosis in a tertiary care hospital, Nepal. BMC Infectious Diseases, 21(1), 825. https://doi.org/10.1186/s12879-021-06562-1
Bhujel R, et al. Comparative Study of Amsel's Criteria and Nugent Scoring for Diagnosis of Bacterial Vaginosis in a Tertiary Care Hospital, Nepal. BMC Infect Dis. 2021 Aug 17;21(1):825. PubMed PMID: 34404367.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparative study of Amsel's criteria and Nugent scoring for diagnosis of bacterial vaginosis in a tertiary care hospital, Nepal. AU - Bhujel,Rajshree, AU - Mishra,Shyam Kumar, AU - Yadav,Santosh Kumar, AU - Bista,Kesang Diki, AU - Parajuli,Keshab, Y1 - 2021/08/17/ PY - 2020/03/05/received PY - 2021/08/11/accepted PY - 2021/8/18/entrez PY - 2021/8/19/pubmed PY - 2021/9/25/medline KW - Amsel’s criteria KW - Bacterial vaginosis KW - Nugent scoring KW - Vaginal discharge SP - 825 EP - 825 JF - BMC infectious diseases JO - BMC Infect Dis VL - 21 IS - 1 N2 - BACKGROUND: The most common pathological cause of abnormal vaginal discharge in reproductive-aged women is bacterial vaginosis (BV). Amsel's criteria and Nugent scoring systems are commonly employed approaches for the diagnosis of BV. Despite the Nugent scoring system being the gold standard method for diagnosing BV, Amsel's criteria are generally preferred in clinical setup owing to the fact Nugent scoring requires considerable time and expert microscopist. This study was conducted to determine the diagnostic value of Amsel's criteria by comparing it with the Nugent scoring system. METHODS: This was a descriptive cross-sectional study conducted at Tribhuvan University Teaching Hospital, Nepal from October 2016 to September 2017. Vaginal specimens were collected from a total of 141 women presenting with abnormal vaginal discharge. The sensitivity, specificity, positive predictive value, and negative predictive value of Amsel's criteria were calculated, and each component of Amsel's criteria was compared to the Nugent scoring system. RESULTS: The sensitivity, specificity, positive predictive value, and negative predictive value of Amsel's criteria were 50%, 98.2%, 87.5%, and 88.8% respectively. The clue cells showed 100% specificity and vaginal discharge with pH > 4.5 had 89.3% sensitivity while compared with Nugent's scoring system. CONCLUSIONS: Amsel's criteria can be used as an adjunct method to Nugent scoring for the diagnosis of BV in the hands of skilled manpower in resources limited countries. The presence of clue cell and positive whiff test of Amsel's criteria shows good match with Nugent's score. SN - 1471-2334 UR - https://www.unboundmedicine.com/medline/citation/34404367/Comparative_study_of_Amsel's_criteria_and_Nugent_scoring_for_diagnosis_of_bacterial_vaginosis_in_a_tertiary_care_hospital_Nepal_ L2 - https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-021-06562-1 DB - PRIME DP - Unbound Medicine ER -