Tags

Type your tag names separated by a space and hit enter

Coronavirus disease 2019 (COVID-19) in a pregnant women with treatment resistance thrombocytopenic purpura with and suspicion to HELLP syndrome: a case report.
BMC Pregnancy Childbirth. 2021 Aug 18; 21(1):567.BP

Abstract

BACKGROUND

Coronavirus disease 2019 (COVID-19) still is a global emergency. According to the studies, pregnant women are of the at risk populations and any underlying disease(s) might even worsen their condition. The aim of this study is reporting a complex case of immune thrombocytopenic purpura (ITP) during pregnancy who has been diagnosed with COVID-19 as well as suspicion of HELLP syndrome.

CASE PRESENTATION

A 24-year-old woman with a platelet count of 6000/mL and resistance to conventional therapies was referred. A day after starting 0.5 g/day of methylprednisolone for her, fever and a decrease in SpO2 presented. According to the paraclinical investigations, COVID-19 was diagnosed and the conventional COVID-19 treatments started for her (the methylprednisolone pulse stopped). Due to the increased liver enzymes and low platelet count, with suspicion of HELLP syndrome, cesarean section surgery was performed which resulted in a healthy neonate. Then, the methylprednisolone pulse was restarted for and she developed an increase in the platelet count.

CONCLUSION

It is not clear how COVID-19 and pregnancy affected the patient's condition and the underlying disease; however, it seems the delivery and/or restarting the methylprednisolone pulses caused improvement in her condition.

Authors+Show Affiliations

Medical Biology Research Center, Health Institute Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran. Maternal, Fetal and Neonatal Research Center, Vali-Asr Hospital, Imam Khomeini Hospital Complexes, Tehran University of Medical Sciences, Tehran, Iran.Department of Obstetrics and Gynecology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.Medical Biology Research Center, Health Institute Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.Maternal, Fetal and Neonatal Research Center, Vali-Asr Hospital, Imam Khomeini Hospital Complexes, Tehran University of Medical Sciences, Tehran, Iran. mahsanaemi@yahoo.com. Fetomaternal Department, Shariati Hospital, Tehran University of Medical Sciences, North-Kargar Avenue, Tehran, Iran. mahsanaemi@yahoo.com.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

34407793

Citation

Norooznezhad, Amir Hossein, et al. "Coronavirus Disease 2019 (COVID-19) in a Pregnant Women With Treatment Resistance Thrombocytopenic Purpura With and Suspicion to HELLP Syndrome: a Case Report." BMC Pregnancy and Childbirth, vol. 21, no. 1, 2021, p. 567.
Norooznezhad AH, Nurzadeh M, Darabi MH, et al. Coronavirus disease 2019 (COVID-19) in a pregnant women with treatment resistance thrombocytopenic purpura with and suspicion to HELLP syndrome: a case report. BMC Pregnancy Childbirth. 2021;21(1):567.
Norooznezhad, A. H., Nurzadeh, M., Darabi, M. H., & Naemi, M. (2021). Coronavirus disease 2019 (COVID-19) in a pregnant women with treatment resistance thrombocytopenic purpura with and suspicion to HELLP syndrome: a case report. BMC Pregnancy and Childbirth, 21(1), 567. https://doi.org/10.1186/s12884-021-04030-x
Norooznezhad AH, et al. Coronavirus Disease 2019 (COVID-19) in a Pregnant Women With Treatment Resistance Thrombocytopenic Purpura With and Suspicion to HELLP Syndrome: a Case Report. BMC Pregnancy Childbirth. 2021 Aug 18;21(1):567. PubMed PMID: 34407793.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Coronavirus disease 2019 (COVID-19) in a pregnant women with treatment resistance thrombocytopenic purpura with and suspicion to HELLP syndrome: a case report. AU - Norooznezhad,Amir Hossein, AU - Nurzadeh,Maryam, AU - Darabi,Mohammad Hasan, AU - Naemi,Mahsa, Y1 - 2021/08/18/ PY - 2021/03/16/received PY - 2021/08/02/accepted PY - 2021/8/19/entrez PY - 2021/8/20/pubmed PY - 2021/8/25/medline KW - COVID-19 KW - Immune thrombocytopenic purpura KW - Immunosuppression KW - Pregnancy SP - 567 EP - 567 JF - BMC pregnancy and childbirth JO - BMC Pregnancy Childbirth VL - 21 IS - 1 N2 - BACKGROUND: Coronavirus disease 2019 (COVID-19) still is a global emergency. According to the studies, pregnant women are of the at risk populations and any underlying disease(s) might even worsen their condition. The aim of this study is reporting a complex case of immune thrombocytopenic purpura (ITP) during pregnancy who has been diagnosed with COVID-19 as well as suspicion of HELLP syndrome. CASE PRESENTATION: A 24-year-old woman with a platelet count of 6000/mL and resistance to conventional therapies was referred. A day after starting 0.5 g/day of methylprednisolone for her, fever and a decrease in SpO2 presented. According to the paraclinical investigations, COVID-19 was diagnosed and the conventional COVID-19 treatments started for her (the methylprednisolone pulse stopped). Due to the increased liver enzymes and low platelet count, with suspicion of HELLP syndrome, cesarean section surgery was performed which resulted in a healthy neonate. Then, the methylprednisolone pulse was restarted for and she developed an increase in the platelet count. CONCLUSION: It is not clear how COVID-19 and pregnancy affected the patient's condition and the underlying disease; however, it seems the delivery and/or restarting the methylprednisolone pulses caused improvement in her condition. SN - 1471-2393 UR - https://www.unboundmedicine.com/medline/citation/34407793/Coronavirus_disease_2019__COVID_19__in_a_pregnant_women_with_treatment_resistance_thrombocytopenic_purpura_with_and_suspicion_to_HELLP_syndrome:_a_case_report_ L2 - https://bmcpregnancychildbirth.biomedcentral.com/articles/10.1186/s12884-021-04030-x DB - PRIME DP - Unbound Medicine ER -