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Rare case of COVID-19 vaccine-associated intracranial haemorrhage with venous sinus thrombosis.
BMJ Case Rep. 2021 Sep 23; 14(9)BC

Abstract

Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a relatively novel term which describes patients who have developed a low platelet count and prothrombotic tendencies secondary to receiving a vaccine. The concept has been derived from the well-established phenomenon of heparin-induced thrombocytopenia, and several cases of VITT have now been reported in patients who have received the AstraZeneca (ChAdOx1 nCov-19) vaccine. Unfortunately, some of these patients have gone on to develop intracranial venous sinus thrombosis. We present a case of VITT-associated sinus thrombosis secondary to the AstraZeneca (ChAdOx1 nCov-19) vaccine, which was complicated by a large intracerebral haemorrhage.

Authors+Show Affiliations

Acute Medicine, Southend Hospital, Westcliff-on-Sea, UK dr.purkayastha@doctors.org.uk.Acute Medicine, Southend Hospital, Westcliff-on-Sea, UK.Acute Medicine, Southend Hospital, Westcliff-on-Sea, UK.Haematology, University College London Hospitals NHS Foundation Trust, London, UK.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

34556531

Citation

Purkayastha, Pujon, et al. "Rare Case of COVID-19 Vaccine-associated Intracranial Haemorrhage With Venous Sinus Thrombosis." BMJ Case Reports, vol. 14, no. 9, 2021.
Purkayastha P, Mckechnie C, Kalkur P, et al. Rare case of COVID-19 vaccine-associated intracranial haemorrhage with venous sinus thrombosis. BMJ Case Rep. 2021;14(9).
Purkayastha, P., Mckechnie, C., Kalkur, P., & Scully, M. (2021). Rare case of COVID-19 vaccine-associated intracranial haemorrhage with venous sinus thrombosis. BMJ Case Reports, 14(9). https://doi.org/10.1136/bcr-2021-245092
Purkayastha P, et al. Rare Case of COVID-19 Vaccine-associated Intracranial Haemorrhage With Venous Sinus Thrombosis. BMJ Case Rep. 2021 Sep 23;14(9) PubMed PMID: 34556531.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Rare case of COVID-19 vaccine-associated intracranial haemorrhage with venous sinus thrombosis. AU - Purkayastha,Pujon, AU - Mckechnie,Charlie, AU - Kalkur,Pallavi, AU - Scully,Marie, Y1 - 2021/09/23/ PY - 2021/9/24/entrez PY - 2021/9/25/pubmed PY - 2021/9/28/medline KW - COVID-19 KW - global health KW - haematology (drugs and medicines) KW - immunological products and vaccines KW - neuroimaging JF - BMJ case reports JO - BMJ Case Rep VL - 14 IS - 9 N2 - Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a relatively novel term which describes patients who have developed a low platelet count and prothrombotic tendencies secondary to receiving a vaccine. The concept has been derived from the well-established phenomenon of heparin-induced thrombocytopenia, and several cases of VITT have now been reported in patients who have received the AstraZeneca (ChAdOx1 nCov-19) vaccine. Unfortunately, some of these patients have gone on to develop intracranial venous sinus thrombosis. We present a case of VITT-associated sinus thrombosis secondary to the AstraZeneca (ChAdOx1 nCov-19) vaccine, which was complicated by a large intracerebral haemorrhage. SN - 1757-790X UR - https://www.unboundmedicine.com/medline/citation/34556531/Rare_case_of_COVID_19_vaccine_associated_intracranial_haemorrhage_with_venous_sinus_thrombosis_ L2 - https://casereports.bmj.com/lookup/pmidlookup?view=long&pmid=34556531 DB - PRIME DP - Unbound Medicine ER -