TY - JOUR T1 - Application of Solid Phase Extraction and High-Performance Liquid Chromatography with Fluorescence Detection to Analyze Bisphenol A Bis (2,3-Dihydroxypropyl) Ether (BADGE 2H2O), Bisphenol F (BPF), and Bisphenol E (BPE) in Human Urine Samples. AU - Tuzimski,Tomasz, AU - Szubartowski,Szymon, Y1 - 2021/09/30/ PY - 2021/08/11/received PY - 2021/09/17/revised PY - 2021/09/28/accepted PY - 2021/10/13/entrez PY - 2021/10/14/pubmed PY - 2021/10/26/medline KW - Scherzo SM-C18 KW - bisphenol A bis (2,3-dihydroxypropyl) ether (BADGE 2H2O) KW - bisphenols KW - dispersive solid phase extraction (d-SPE) KW - fluorescence detector (FLD) KW - human urine samples KW - solid phase extraction (SPE) JF - International journal of environmental research and public health JO - Int J Environ Res Public Health VL - 18 IS - 19 N2 - In this study, we propose a simple, cost-effective, and sensitive high-performance liquid chromatography method with fluorescence detection (HPLC-FLD) for the simultaneous determination of the three bisphenols (BPs): bisphenol A bis (2,3-dihydroxypropyl) ether (BADGE 2H2O), bisphenol F (BPF), and bisphenol E (BPE) in human urine samples. The dispersive solid phase extraction (d-SPE) coupled with solid phase extraction (SPE) procedure performed well for the analytes with recoveries in the range of 74.3-86.5% and relative standard deviations (RSD%) less than 10%. The limits of quantification (LOQs) for all investigated analytes were in the range of 11.42-22.35 ng mL-1. The method was validated at three concentration levels (1 × LOQ, 1.5 × LOQ, and 3 LOQ). During the bisphenols HPLC-FLD analysis, from 6 min a reinforcement (10 or 12) was used, therefore analytes might be identified in the small volume human urine samples. The results demonstrated clearly that the approach developed provides reliable, simple, and rapid quantification and identification of three bisphenols in a urine matrix and could be used for monitoring these analytes. SN - 1660-4601 UR - https://www.unboundmedicine.com/medline/citation/34639606/Application_of_Solid_Phase_Extraction_and_High_Performance_Liquid_Chromatography_with_Fluorescence_Detection_to_Analyze_Bisphenol_A_Bis__23_Dihydroxypropyl__Ether__BADGE_2H2O__Bisphenol_F__BPF__and_Bisphenol_E__BPE__in_Human_Urine_Samples_ DB - PRIME DP - Unbound Medicine ER -