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The Antimicrobial Activities of Silver Nanoparticles from Aqueous Extract of Grape Seeds against Pathogenic Bacteria and Fungi.
Molecules. 2021 Oct 08; 26(19)M

Abstract

Grape seed extract (GSE) is a natural source of polyphenolic compounds and secondary metabolites, which have been tested for their possible antimicrobial activities. In the current study, we tested the antibacterial and antifungal activities of aqueous GSE and the biosynthesized silver nanoparticles loaded with GSE (GSE-AgNPs) against different pathogens. The biosynthesized GSE-AgNPs were assessed by UV spectroscopy, dynamic light scattering (DLS), field emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM), Fourier-transform infrared spectroscopy (FTIR), and gas chromatography/mass spectrometry (GC/MS). The antimicrobial activities were assessed against different bacterial and fungal species. DLS analysis showed that GSE-AgNPs had a Z-Average of 91.89 nm while UV spectroscopy showed that GSE-AgNPs had the highest absorbance at a wavelength of ~415 nm. FTIR analysis revealed that both of GSE and GSE-AgNPs consisted of different functional groups, such as hydroxyl, alkenes, alkyne, and aromatic rings. Both FE-SEM and TEM showed that GSE-AgNPs had larger sizes and rough surfaces than GSE and AgNO3. The results showed significant antimicrobial activities of GSE-AgNPs against all tested species, unlike GSE, which had weaker and limited effects. More studies are needed to investigate the other antimicrobial activities of GSE.

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Authors+Show Affiliations

Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box 22452, Riyadh 11495, Saudi Arabia.

Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box 22452, Riyadh 11495, Saudi Arabia.

Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box 22452, Riyadh 11495, Saudi Arabia.

Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box 22452, Riyadh 11495, Saudi Arabia.

Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box 22452, Riyadh 11495, Saudi Arabia.

Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box 22452, Riyadh 11495, Saudi Arabia.

MeSH

Anti-Bacterial AgentsAntifungal AgentsBacteriaDynamic Light ScatteringFungiGrape Seed ExtractMetal NanoparticlesMicrobial Sensitivity TestsMicrobial ViabilityMolecular StructureParticle SizeSilverSpectroscopy, Fourier Transform Infrared

Pub Type(s)

Journal Article

Language

eng

PubMed ID

34641623

Citation

Al-Otibi, Fatimah, et al. "The Antimicrobial Activities of Silver Nanoparticles From Aqueous Extract of Grape Seeds Against Pathogenic Bacteria and Fungi." Molecules (Basel, Switzerland), vol. 26, no. 19, 2021.

Al-Otibi F, Alkhudhair SK, Alharbi RI, et al. The Antimicrobial Activities of Silver Nanoparticles from Aqueous Extract of Grape Seeds against Pathogenic Bacteria and Fungi. Molecules. 2021;26(19).

Al-Otibi, F., Alkhudhair, S. K., Alharbi, R. I., Al-Askar, A. A., Aljowaie, R. M., & Al-Shehri, S. (2021). The Antimicrobial Activities of Silver Nanoparticles from Aqueous Extract of Grape Seeds against Pathogenic Bacteria and Fungi. Molecules (Basel, Switzerland), 26(19). https://doi.org/10.3390/molecules26196081

Al-Otibi F, et al. The Antimicrobial Activities of Silver Nanoparticles From Aqueous Extract of Grape Seeds Against Pathogenic Bacteria and Fungi. Molecules. 2021 Oct 8;26(19) PubMed PMID: 34641623.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - The Antimicrobial Activities of Silver Nanoparticles from Aqueous Extract of Grape Seeds against Pathogenic Bacteria and Fungi. AU - Al-Otibi,Fatimah, AU - Alkhudhair,Shahad K, AU - Alharbi,Raedah I, AU - Al-Askar,Abdulaziz A, AU - Aljowaie,Reem M, AU - Al-Shehri,Sameha, Y1 - 2021/10/08/ PY - 2021/09/11/received PY - 2021/10/04/revised PY - 2021/10/05/accepted PY - 2021/10/13/entrez PY - 2021/10/14/pubmed PY - 2021/11/17/medline KW - DLS KW - FE-SEM KW - FTIR KW - GC/MS KW - TEM KW - UV spectroscopy KW - antimicrobial activities KW - grape seed extract KW - sliver nanoparticles JF - Molecules (Basel, Switzerland) JO - Molecules VL - 26 IS - 19 N2 - Grape seed extract (GSE) is a natural source of polyphenolic compounds and secondary metabolites, which have been tested for their possible antimicrobial activities. In the current study, we tested the antibacterial and antifungal activities of aqueous GSE and the biosynthesized silver nanoparticles loaded with GSE (GSE-AgNPs) against different pathogens. The biosynthesized GSE-AgNPs were assessed by UV spectroscopy, dynamic light scattering (DLS), field emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM), Fourier-transform infrared spectroscopy (FTIR), and gas chromatography/mass spectrometry (GC/MS). The antimicrobial activities were assessed against different bacterial and fungal species. DLS analysis showed that GSE-AgNPs had a Z-Average of 91.89 nm while UV spectroscopy showed that GSE-AgNPs had the highest absorbance at a wavelength of ~415 nm. FTIR analysis revealed that both of GSE and GSE-AgNPs consisted of different functional groups, such as hydroxyl, alkenes, alkyne, and aromatic rings. Both FE-SEM and TEM showed that GSE-AgNPs had larger sizes and rough surfaces than GSE and AgNO3. The results showed significant antimicrobial activities of GSE-AgNPs against all tested species, unlike GSE, which had weaker and limited effects. More studies are needed to investigate the other antimicrobial activities of GSE. SN - 1420-3049 UR - https://www.unboundmedicine.com/medline/citation/34641623/The_Antimicrobial_Activities_of_Silver_Nanoparticles_from_Aqueous_Extract_of_Grape_Seeds_against_Pathogenic_Bacteria_and_Fungi_ DB - PRIME DP - Unbound Medicine ER -