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Clinical Evaluation of Pinggan Yiqi Yangshen Recipe Combined with Labetalol Hydrochloride and Magnesium Sulfate in the Treatment of PIH.
Evid Based Complement Alternat Med. 2021; 2021:3135043.EB

Abstract

BACKGROUND

To observe the clinical effect of Pinggan Yiqi Yangshen recipe combined with labetalol hydrochloride and magnesium sulfate in the treatment of pregnancy-induced hypertension (PIH).

METHODS

A total of 126 patients with PIH diagnosed in our hospital from January 2016 to May 2018 were randomly divided into the control group and the experimental group, with 63 cases in each group. The control group was treated with labetalol combined with magnesium sulfate. On the basis of the control group, the experimental group was treated with Pinggan Yiqi Yangshen recipe. Clinical efficacy, blood pressure, renal function, and biochemical indexes were compared between the two groups. Moreover, pregnancy outcomes and adverse reactions were compared between the two groups.

RESULTS

After treatment, the total effective rate in the experimental group was higher than in the control group. Blood pressure and mean arterial pressure in the experimental group were more significantly downregulated than the control group. Renal function indexes and biochemical indexes in the experimental group were more significant than those in the control group. The incidence of cesarean section, preterm birth, and abnormal fetal heart rate in the experimental group was significantly lower than that in the control group. There was no difference in the incidence of fetal distress, postpartum hemorrhage, neonatal asphyxia, and adverse reactions between the two groups.

CONCLUSION

Pinggan Yiqi Yangshen recipe combined with labetalol hydrochloride and magnesium sulfate can effectively reduce the blood pressure of patients with PIH, help patients to return to normal levels of biochemical indexes and renal function indexes, and improve pregnancy outcomes with high safety, which is worthy of further promotion and application in clinical practice.

Authors+Show Affiliations

Health Education Department, Zhangqiu Maternity and Child Care Hospital, Jinan 250200, China.Outpatient Department, Zhangqiu Maternity and Child Care Hospital, Jinan 250200, China.Comprehensive Ward, Zhangqiu Maternity and Child Care Hospital, Jinan 250200, China.Outpatient Operating Room, Zhangqiu Maternity and Child Care Hospital, Jinan 250200, China.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

34745277

Citation

Li, Ping, et al. "Clinical Evaluation of Pinggan Yiqi Yangshen Recipe Combined With Labetalol Hydrochloride and Magnesium Sulfate in the Treatment of PIH." Evidence-based Complementary and Alternative Medicine : ECAM, vol. 2021, 2021, p. 3135043.
Li P, Zhao J, Gao P, et al. Clinical Evaluation of Pinggan Yiqi Yangshen Recipe Combined with Labetalol Hydrochloride and Magnesium Sulfate in the Treatment of PIH. Evid Based Complement Alternat Med. 2021;2021:3135043.
Li, P., Zhao, J., Gao, P., & Qu, H. (2021). Clinical Evaluation of Pinggan Yiqi Yangshen Recipe Combined with Labetalol Hydrochloride and Magnesium Sulfate in the Treatment of PIH. Evidence-based Complementary and Alternative Medicine : ECAM, 2021, 3135043. https://doi.org/10.1155/2021/3135043
Li P, et al. Clinical Evaluation of Pinggan Yiqi Yangshen Recipe Combined With Labetalol Hydrochloride and Magnesium Sulfate in the Treatment of PIH. Evid Based Complement Alternat Med. 2021;2021:3135043. PubMed PMID: 34745277.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical Evaluation of Pinggan Yiqi Yangshen Recipe Combined with Labetalol Hydrochloride and Magnesium Sulfate in the Treatment of PIH. AU - Li,Ping, AU - Zhao,Jie, AU - Gao,Peipei, AU - Qu,Hongcui, Y1 - 2021/10/28/ PY - 2021/09/06/received PY - 2021/10/18/accepted PY - 2021/11/8/entrez PY - 2021/11/9/pubmed PY - 2021/11/9/medline SP - 3135043 EP - 3135043 JF - Evidence-based complementary and alternative medicine : eCAM JO - Evid Based Complement Alternat Med VL - 2021 N2 - BACKGROUND: To observe the clinical effect of Pinggan Yiqi Yangshen recipe combined with labetalol hydrochloride and magnesium sulfate in the treatment of pregnancy-induced hypertension (PIH). METHODS: A total of 126 patients with PIH diagnosed in our hospital from January 2016 to May 2018 were randomly divided into the control group and the experimental group, with 63 cases in each group. The control group was treated with labetalol combined with magnesium sulfate. On the basis of the control group, the experimental group was treated with Pinggan Yiqi Yangshen recipe. Clinical efficacy, blood pressure, renal function, and biochemical indexes were compared between the two groups. Moreover, pregnancy outcomes and adverse reactions were compared between the two groups. RESULTS: After treatment, the total effective rate in the experimental group was higher than in the control group. Blood pressure and mean arterial pressure in the experimental group were more significantly downregulated than the control group. Renal function indexes and biochemical indexes in the experimental group were more significant than those in the control group. The incidence of cesarean section, preterm birth, and abnormal fetal heart rate in the experimental group was significantly lower than that in the control group. There was no difference in the incidence of fetal distress, postpartum hemorrhage, neonatal asphyxia, and adverse reactions between the two groups. CONCLUSION: Pinggan Yiqi Yangshen recipe combined with labetalol hydrochloride and magnesium sulfate can effectively reduce the blood pressure of patients with PIH, help patients to return to normal levels of biochemical indexes and renal function indexes, and improve pregnancy outcomes with high safety, which is worthy of further promotion and application in clinical practice. SN - 1741-427X UR - https://www.unboundmedicine.com/medline/citation/34745277/Clinical_Evaluation_of_Pinggan_Yiqi_Yangshen_Recipe_Combined_with_Labetalol_Hydrochloride_and_Magnesium_Sulfate_in_the_Treatment_of_PIH_ DB - PRIME DP - Unbound Medicine ER -
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