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Cardiovascular risk factors from birth to 7 years of age: the Bogalusa Heart Study. Serum lipids and lipoproteins.
Pediatrics 1987; 80(5 Pt 2):789-96Ped

Abstract

Serum lipids and lipoprotein cholesterol fractions were examined in a newborn cohort that was followed from birth to 7 years of age. Although white and female infants had higher cord blood levels of high-density lipoprotein cholesterol (HDL-C) than did black and male infants, respectively, these differences did not persist throughout early childhood. Mean levels of all serum lipids and lipoproteins increased greatly in the first 6 months of life, and by 2 years of age, levels approached those seen in adolescents. Infants consuming cow's milk had higher 6-month levels of serum total cholesterol and low-density lipoprotein cholesterol than did formula-fed infants. However, milk source in infancy did not significantly influence total cholesterol or low-density lipoprotein cholesterol levels at age 7 years. Serum lipid and lipoprotein levels at age 7 years were associated with previously measured levels as early as 6 months of age, and infants with unfavorable levels were likely to have similar adverse levels at 7 years of age. In addition, increases in obesity between 6 months and 7 years of age were positively associated with increases in levels of serum triglycerides. These results suggest that certain persons at increased risk for cardiovascular disease can be identified in infancy.

Authors+Show Affiliations

Department of Medicine, Louisiana State University Medical Center, New Orleans.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

3478647

Citation

Freedman, D S., et al. "Cardiovascular Risk Factors From Birth to 7 Years of Age: the Bogalusa Heart Study. Serum Lipids and Lipoproteins." Pediatrics, vol. 80, no. 5 Pt 2, 1987, pp. 789-96.
Freedman DS, Srinivasan SR, Cresanta JL, et al. Cardiovascular risk factors from birth to 7 years of age: the Bogalusa Heart Study. Serum lipids and lipoproteins. Pediatrics. 1987;80(5 Pt 2):789-96.
Freedman, D. S., Srinivasan, S. R., Cresanta, J. L., Webber, L. S., & Berenson, G. S. (1987). Cardiovascular risk factors from birth to 7 years of age: the Bogalusa Heart Study. Serum lipids and lipoproteins. Pediatrics, 80(5 Pt 2), pp. 789-96.
Freedman DS, et al. Cardiovascular Risk Factors From Birth to 7 Years of Age: the Bogalusa Heart Study. Serum Lipids and Lipoproteins. Pediatrics. 1987;80(5 Pt 2):789-96. PubMed PMID: 3478647.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cardiovascular risk factors from birth to 7 years of age: the Bogalusa Heart Study. Serum lipids and lipoproteins. AU - Freedman,D S, AU - Srinivasan,S R, AU - Cresanta,J L, AU - Webber,L S, AU - Berenson,G S, PY - 1987/11/1/pubmed PY - 1987/11/1/medline PY - 1987/11/1/entrez SP - 789 EP - 96 JF - Pediatrics JO - Pediatrics VL - 80 IS - 5 Pt 2 N2 - Serum lipids and lipoprotein cholesterol fractions were examined in a newborn cohort that was followed from birth to 7 years of age. Although white and female infants had higher cord blood levels of high-density lipoprotein cholesterol (HDL-C) than did black and male infants, respectively, these differences did not persist throughout early childhood. Mean levels of all serum lipids and lipoproteins increased greatly in the first 6 months of life, and by 2 years of age, levels approached those seen in adolescents. Infants consuming cow's milk had higher 6-month levels of serum total cholesterol and low-density lipoprotein cholesterol than did formula-fed infants. However, milk source in infancy did not significantly influence total cholesterol or low-density lipoprotein cholesterol levels at age 7 years. Serum lipid and lipoprotein levels at age 7 years were associated with previously measured levels as early as 6 months of age, and infants with unfavorable levels were likely to have similar adverse levels at 7 years of age. In addition, increases in obesity between 6 months and 7 years of age were positively associated with increases in levels of serum triglycerides. These results suggest that certain persons at increased risk for cardiovascular disease can be identified in infancy. SN - 0031-4005 UR - https://www.unboundmedicine.com/medline/citation/3478647/Cardiovascular_risk_factors_from_birth_to_7_years_of_age:_the_Bogalusa_Heart_Study__Serum_lipids_and_lipoproteins_ L2 - http://pediatrics.aappublications.org/cgi/pmidlookup?view=long&pmid=3478647 DB - PRIME DP - Unbound Medicine ER -