Abstract
Diagnostics, vaccines, and drugs are indispensable tools and control measures employed to overcome infectious diseases such as coronavirus disease 2019 (COVID-19). Diagnostic tools based on RT-PCR were developed early in the COVID-19 pandemic and were urgently required for quarantine (testing, tracing and isolation). Vaccines such as mRNA vaccines and virus-vectored vaccines were also successfully developed using new platform technologies within one year after identifying severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as the causative agent of COVID-19. Drug development has been conducted in various ways including drug repurposing, convalescent plasma therapy, and monoclonal antibody development. Among the above efforts, this review examines COVID-19 drug development along with the related and upcoming challenges.
TY - JOUR
T1 - COVID-19 Drug Development.
A1 - Kim,Seungtaek,
PY - 2021/10/19/received
PY - 2021/11/23/revised
PY - 2021/11/29/accepted
PY - 2021/12/7/pubmed
PY - 2022/2/9/medline
PY - 2021/12/6/entrez
KW - COVID-19
KW - SARS-CoV-2
KW - convalescent plasma
KW - drug repurposing
KW - monoclonal antibody
SP - 1
EP - 5
JF - Journal of microbiology and biotechnology
JO - J Microbiol Biotechnol
VL - 32
IS - 1
N2 - Diagnostics, vaccines, and drugs are indispensable tools and control measures employed to overcome infectious diseases such as coronavirus disease 2019 (COVID-19). Diagnostic tools based on RT-PCR were developed early in the COVID-19 pandemic and were urgently required for quarantine (testing, tracing and isolation). Vaccines such as mRNA vaccines and virus-vectored vaccines were also successfully developed using new platform technologies within one year after identifying severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as the causative agent of COVID-19. Drug development has been conducted in various ways including drug repurposing, convalescent plasma therapy, and monoclonal antibody development. Among the above efforts, this review examines COVID-19 drug development along with the related and upcoming challenges.
SN - 1738-8872
UR - https://www.unboundmedicine.com/medline/citation/34866128/COVID_19_Drug_Development_
DB - PRIME
DP - Unbound Medicine
ER -