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[Prevention of recurrent hemorrhage due to portal hypertension].
Schweiz Med Wochenschr. 1986 Apr 26; 116(17):552-4.SM

Abstract

Gastrointestinal bleeding due to portal hypertension is a severe complication in patients with cirrhosis. Recurrent hemorrhage occurs in 75% of patients at 2 years, and medical treatment aims to induce a permanent decrease in portal pressure. A controlled study demonstrated that continuous administration of propranolol significantly decreased the risk of recurrent gastrointestinal bleeding in selected cirrhotic patients in good health. This efficacy was not found in unselected patients. The risk of recurrent gastrointestinal bleeding correlates with the development of hepatocellular carcinoma and poor compliance. Sclerotherapy of esophageal varices consists in obstruction of the varicosities. It has been demonstrated that esophageal sclerotherapy significantly reduces recurrent gastrointestinal bleeding, although a number of complications may occur.

Authors

Lebrec D
No affiliation info available

MeSH

Double-Blind MethodEsophageal and Gastric VaricesEsophagoscopyGastrointestinal HemorrhageHumansHypertension, PortalPropranololProspective StudiesRandom AllocationRecurrenceSclerosing Solutions

Pub Type(s)

English Abstract
Journal Article

Language

fre

PubMed ID

3487112

Citation

Lebrec, D. "[Prevention of Recurrent Hemorrhage Due to Portal Hypertension]." Schweizerische Medizinische Wochenschrift, vol. 116, no. 17, 1986, pp. 552-4.
Lebrec D. [Prevention of recurrent hemorrhage due to portal hypertension]. Schweiz Med Wochenschr. 1986;116(17):552-4.
Lebrec, D. (1986). [Prevention of recurrent hemorrhage due to portal hypertension]. Schweizerische Medizinische Wochenschrift, 116(17), 552-4.
Lebrec D. [Prevention of Recurrent Hemorrhage Due to Portal Hypertension]. Schweiz Med Wochenschr. 1986 Apr 26;116(17):552-4. PubMed PMID: 3487112.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Prevention of recurrent hemorrhage due to portal hypertension]. A1 - Lebrec,D, PY - 1986/4/26/pubmed PY - 1986/4/26/medline PY - 1986/4/26/entrez SP - 552 EP - 4 JF - Schweizerische medizinische Wochenschrift JO - Schweiz Med Wochenschr VL - 116 IS - 17 N2 - Gastrointestinal bleeding due to portal hypertension is a severe complication in patients with cirrhosis. Recurrent hemorrhage occurs in 75% of patients at 2 years, and medical treatment aims to induce a permanent decrease in portal pressure. A controlled study demonstrated that continuous administration of propranolol significantly decreased the risk of recurrent gastrointestinal bleeding in selected cirrhotic patients in good health. This efficacy was not found in unselected patients. The risk of recurrent gastrointestinal bleeding correlates with the development of hepatocellular carcinoma and poor compliance. Sclerotherapy of esophageal varices consists in obstruction of the varicosities. It has been demonstrated that esophageal sclerotherapy significantly reduces recurrent gastrointestinal bleeding, although a number of complications may occur. SN - 0036-7672 UR - https://www.unboundmedicine.com/medline/citation/3487112/[Prevention_of_recurrent_hemorrhage_due_to_portal_hypertension]_ L2 - http://www.diseaseinfosearch.org/result/5881 DB - PRIME DP - Unbound Medicine ER -