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The role of bronchoalveolar lavage in the diagnosis of suspected opportunistic pneumonia.
Aust N Z J Med. 1987 Aug; 17(4):407-12.AN

Abstract

We report 50 immunocompromised patients with pulmonary infiltrates who underwent fibreoptic bronchoscopy, including bronchoalveolar lavage, on 56 occasions. The underlying diseases were mostly lymphoma, leukemia, other malignancies and renal failure. The commonest immunodeficiency factors were chemotherapy, steroids and neutropenia. A positive diagnosis could be made from analysis of the bronchoalveolar lavage on 59% (33/56) occasions. This was a comparable yield to transbronchial lung biopsy 57% (16/27), and superior to proximal airways wash 24% (13/55), or bronchial brushings 29% (10/34). Open lung biopsy added additional diagnostic information in three of the four cases in which it was performed. The most common final diagnoses were bacterial, viral or Pneumocystis carinii pneumonia and recurrent malignancy. We conclude that bronchoalveolar lavage is a safe procedure with a high diagnostic yield in the immunocompromised host with suspected opportunistic pneumonia.

Authors+Show Affiliations

Abramson MJ
Faculty of Medicine, University of Newcastle, NSW.
Stone CA
No affiliation info available
Holmes PW
No affiliation info available
Tai EH
No affiliation info available

MeSH

Bacterial InfectionsBiopsyBronchoalveolar Lavage FluidBronchoscopyHumansLungLung NeoplasmsOpportunistic InfectionsPneumoniaPneumonia, MycoplasmaPneumonia, PneumocystisPneumonia, Viral

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

3501711

Citation

Abramson, M J., et al. "The Role of Bronchoalveolar Lavage in the Diagnosis of Suspected Opportunistic Pneumonia." Australian and New Zealand Journal of Medicine, vol. 17, no. 4, 1987, pp. 407-12.
Abramson MJ, Stone CA, Holmes PW, et al. The role of bronchoalveolar lavage in the diagnosis of suspected opportunistic pneumonia. Aust N Z J Med. 1987;17(4):407-12.
Abramson, M. J., Stone, C. A., Holmes, P. W., & Tai, E. H. (1987). The role of bronchoalveolar lavage in the diagnosis of suspected opportunistic pneumonia. Australian and New Zealand Journal of Medicine, 17(4), 407-12.
Abramson MJ, et al. The Role of Bronchoalveolar Lavage in the Diagnosis of Suspected Opportunistic Pneumonia. Aust N Z J Med. 1987;17(4):407-12. PubMed PMID: 3501711.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The role of bronchoalveolar lavage in the diagnosis of suspected opportunistic pneumonia. AU - Abramson,M J, AU - Stone,C A, AU - Holmes,P W, AU - Tai,E H, PY - 1987/8/1/pubmed PY - 1987/8/1/medline PY - 1987/8/1/entrez SP - 407 EP - 12 JF - Australian and New Zealand journal of medicine JO - Aust N Z J Med VL - 17 IS - 4 N2 - We report 50 immunocompromised patients with pulmonary infiltrates who underwent fibreoptic bronchoscopy, including bronchoalveolar lavage, on 56 occasions. The underlying diseases were mostly lymphoma, leukemia, other malignancies and renal failure. The commonest immunodeficiency factors were chemotherapy, steroids and neutropenia. A positive diagnosis could be made from analysis of the bronchoalveolar lavage on 59% (33/56) occasions. This was a comparable yield to transbronchial lung biopsy 57% (16/27), and superior to proximal airways wash 24% (13/55), or bronchial brushings 29% (10/34). Open lung biopsy added additional diagnostic information in three of the four cases in which it was performed. The most common final diagnoses were bacterial, viral or Pneumocystis carinii pneumonia and recurrent malignancy. We conclude that bronchoalveolar lavage is a safe procedure with a high diagnostic yield in the immunocompromised host with suspected opportunistic pneumonia. SN - 0004-8291 UR - https://www.unboundmedicine.com/medline/citation/3501711/The_role_of_bronchoalveolar_lavage_in_the_diagnosis_of_suspected_opportunistic_pneumonia_ DB - PRIME DP - Unbound Medicine ER -