Tags

Type your tag names separated by a space and hit enter

A randomized sham-controlled trial of manual acupuncture for infertile women with polycystic ovary syndrome.
Integr Med Res. 2022 Jun; 11(2):100830.IM

Abstract

BACKGROUND

Polycystic ovary syndrome (PCOS) is a complex polygenic disease and is one of the most common endocrinological and reproductive disorders. The purpose of this study was to evaluate the efficacy of acupuncture combined with herbal medicine among infertile females with polycystic ovary syndrome (PCOS).

METHOD

A total of 86 women with PCOS, experiencing infertility, were recruited and randomly assigned to receive either manual acupuncture (MA) or sham acupuncture (SA) twice per week for three menstrual cycles. Both groups received herbal medication. The evaluations were conducted after three menstrual cycles and 24 weeks' follow-up.

RESULTS

The trial was completed by 79 (91.86%) of the 86 randomly selected patients. During this study, the pregnancy rate in the MA group (46.34%) was significantly higher than the SA group (18.42%), with a P-value of 0.008. Moreover, the ovulation rate of the MA group (58.14%) was higher than that of the SA group (45.74%), with a P-value of 0.046. The improvement rate of PCOS score and testosterone level showed a statistical difference between the two groups (P-values were <0.05). There were no other differences between the two groups. Sex hormones level, including E2, T, P, LH, and LH/FSH were significantly lower after intervention in the MA group (P-values were <0.05) compared with baseline, while only the progesterone level was reduced in the SA group (P-value = 0.008).

CONCLUSION

Manual acupuncture combined with herbal medicine may be clinically useful for infertile women with PCOS in improving pregnancy and ovulation rate.

TRIAL REGISTRATION

Chinese Clinical Trial Registry: ChiCTR1800014997.

Links

Authors+Show Affiliations

Acupuncture-moxibustion & Tuina School, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Acupuncture-moxibustion & Tuina School, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Acupuncture-moxibustion & Tuina School, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Shanghai Pudong New District Hospital of Traditional Chinese Medicine, Shanghai, China.

Acupuncture-moxibustion & Tuina School, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Acupuncture-moxibustion & Tuina School, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Acupuncture-moxibustion & Tuina School, Shanghai University of Traditional Chinese Medicine, Shanghai, China. Shanghai Pudong New District Hospital of Traditional Chinese Medicine, Shanghai, China.

Pub Type(s)

Journal Article

Review

Language

eng

PubMed ID

35059289

Citation

Pan, Wen, et al. "A Randomized Sham-controlled Trial of Manual Acupuncture for Infertile Women With Polycystic Ovary Syndrome." Integrative Medicine Research, vol. 11, no. 2, 2022, p. 100830.

Pan W, Li FX, Wang Q, et al. A randomized sham-controlled trial of manual acupuncture for infertile women with polycystic ovary syndrome. Integr Med Res. 2022;11(2):100830.

Pan, W., Li, F. X., Wang, Q., Huang, Z. Q., Yan, Y. M., Zhao, L., & Shen, X. Y. (2022). A randomized sham-controlled trial of manual acupuncture for infertile women with polycystic ovary syndrome. Integrative Medicine Research, 11(2), 100830. https://doi.org/10.1016/j.imr.2021.100830

Pan W, et al. A Randomized Sham-controlled Trial of Manual Acupuncture for Infertile Women With Polycystic Ovary Syndrome. Integr Med Res. 2022;11(2):100830. PubMed PMID: 35059289.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - A randomized sham-controlled trial of manual acupuncture for infertile women with polycystic ovary syndrome. AU - Pan,Wen, AU - Li,Feng-Xing, AU - Wang,Qiao, AU - Huang,Zou-Qin, AU - Yan,Yu-Ming, AU - Zhao,Ling, AU - Shen,Xue-Yong, Y1 - 2021/12/28/ PY - 2021/10/12/received PY - 2021/12/17/revised PY - 2021/12/27/accepted PY - 2022/1/21/entrez PY - 2022/1/22/pubmed PY - 2022/1/22/medline KW - Chinese Herbal Medicine KW - Infertility KW - Manual acupuncture KW - Polycystic ovary syndrome SP - 100830 EP - 100830 JF - Integrative medicine research JO - Integr Med Res VL - 11 IS - 2 N2 - BACKGROUND: Polycystic ovary syndrome (PCOS) is a complex polygenic disease and is one of the most common endocrinological and reproductive disorders. The purpose of this study was to evaluate the efficacy of acupuncture combined with herbal medicine among infertile females with polycystic ovary syndrome (PCOS). METHOD: A total of 86 women with PCOS, experiencing infertility, were recruited and randomly assigned to receive either manual acupuncture (MA) or sham acupuncture (SA) twice per week for three menstrual cycles. Both groups received herbal medication. The evaluations were conducted after three menstrual cycles and 24 weeks' follow-up. RESULTS: The trial was completed by 79 (91.86%) of the 86 randomly selected patients. During this study, the pregnancy rate in the MA group (46.34%) was significantly higher than the SA group (18.42%), with a P-value of 0.008. Moreover, the ovulation rate of the MA group (58.14%) was higher than that of the SA group (45.74%), with a P-value of 0.046. The improvement rate of PCOS score and testosterone level showed a statistical difference between the two groups (P-values were <0.05). There were no other differences between the two groups. Sex hormones level, including E2, T, P, LH, and LH/FSH were significantly lower after intervention in the MA group (P-values were <0.05) compared with baseline, while only the progesterone level was reduced in the SA group (P-value = 0.008). CONCLUSION: Manual acupuncture combined with herbal medicine may be clinically useful for infertile women with PCOS in improving pregnancy and ovulation rate. TRIAL REGISTRATION: Chinese Clinical Trial Registry: ChiCTR1800014997. SN - 2213-4220 UR - https://www.unboundmedicine.com/medline/citation/35059289/A_randomized_sham_controlled_trial_of_manual_acupuncture_for_infertile_women_with_polycystic_ovary_syndrome_ DB - PRIME DP - Unbound Medicine ER -