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Acceptance of a Third Dose of COVID-19 Vaccine and Associated Factors in China Based on Health Belief Model: A National Cross-Sectional Study.
Vaccines (Basel). 2022 Jan 07; 10(1)V

Abstract

COVID-19 infections are returning to many countries because of the emergence of variants or declining antibody levels provided by vaccines. An additional dose of vaccination is recommended to be a considerable supplementary intervention. We aim to explore public acceptance of the third dose of the COVID-19 vaccine and related influencing factors in China. This nationwide cross-sectional study was conducted in the general population among 31 provinces in November, 2021. We collected information on basic characteristics, vaccination knowledge and attitudes, and vaccine-related health beliefs of the participants. Univariable and multivariable logistic regression models were used to assess factors associated with the acceptance of a third COVID-19 vaccine. A total of 93.7% (95% CI: 92.9-94.6%) of 3119 Chinese residents were willing to receive a third dose of the COVID-19 vaccine. Individuals with low level of perceived susceptibility, perceived benefit, cues to action cues, and high level of perceived barriers, old age, low educational level, low monthly household income, and low knowledge score on COVID-19 were less likely to have the acceptance of a third dose of COVID-19 (all p < 0.05). In the multivariable logistic regression model, acceptance of the third dose of COVID-19 vaccine was mainly related to previous vaccination history [Sinopharm BBIP (aOR = 6.55, 95% CI 3.30-12.98), Sinovac (aOR = 5.22, 95% CI:2.72-10.02), Convidecia (aOR = 5.80, 95% CI: 2.04-16.48)], high level of perceived susceptibility (aOR = 2.48, 95% CI: 1.48-4.31) and high level of action cues (aOR = 23.66, 95% CI: 9.97-56.23). Overall, residents in China showed a high willingness to accept the third dose of COVID-19 vaccines, which can help vaccine manufacturers in China to manage the vaccine production and distribution for the huge domestic and international vaccine demand. Relevant institutions could increase people's willingness to booster shots by increasing initial COVID-19 vaccination rates, public's perception of COVID-19 susceptibility and cues to action through various strategies and channels. Meanwhile, it also has certain reference significance for other countries to formulate vaccine promotion strategies.

Authors+Show Affiliations

Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.Research Center of Clinical Epidemiology, Peking University Third Hospital, Beijing 100083, China.Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China. Institute for Global Health and Development, Peking University, Beijing 100871, China. National Health Commission Key Laboratory of Reproductive Health, Peking University, Beijing 100191, China.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

35062750

Citation

Qin, Chenyuan, et al. "Acceptance of a Third Dose of COVID-19 Vaccine and Associated Factors in China Based On Health Belief Model: a National Cross-Sectional Study." Vaccines, vol. 10, no. 1, 2022.
Qin C, Wang R, Tao L, et al. Acceptance of a Third Dose of COVID-19 Vaccine and Associated Factors in China Based on Health Belief Model: A National Cross-Sectional Study. Vaccines (Basel). 2022;10(1).
Qin, C., Wang, R., Tao, L., Liu, M., & Liu, J. (2022). Acceptance of a Third Dose of COVID-19 Vaccine and Associated Factors in China Based on Health Belief Model: A National Cross-Sectional Study. Vaccines, 10(1). https://doi.org/10.3390/vaccines10010089
Qin C, et al. Acceptance of a Third Dose of COVID-19 Vaccine and Associated Factors in China Based On Health Belief Model: a National Cross-Sectional Study. Vaccines (Basel). 2022 Jan 7;10(1) PubMed PMID: 35062750.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acceptance of a Third Dose of COVID-19 Vaccine and Associated Factors in China Based on Health Belief Model: A National Cross-Sectional Study. AU - Qin,Chenyuan, AU - Wang,Ruitong, AU - Tao,Liyuan, AU - Liu,Min, AU - Liu,Jue, Y1 - 2022/01/07/ PY - 2021/11/27/received PY - 2021/12/30/revised PY - 2022/01/05/accepted PY - 2022/1/22/entrez PY - 2022/1/23/pubmed PY - 2022/1/23/medline KW - COVID-19 KW - acceptance KW - associated factors KW - third dose KW - vaccination JF - Vaccines JO - Vaccines (Basel) VL - 10 IS - 1 N2 - COVID-19 infections are returning to many countries because of the emergence of variants or declining antibody levels provided by vaccines. An additional dose of vaccination is recommended to be a considerable supplementary intervention. We aim to explore public acceptance of the third dose of the COVID-19 vaccine and related influencing factors in China. This nationwide cross-sectional study was conducted in the general population among 31 provinces in November, 2021. We collected information on basic characteristics, vaccination knowledge and attitudes, and vaccine-related health beliefs of the participants. Univariable and multivariable logistic regression models were used to assess factors associated with the acceptance of a third COVID-19 vaccine. A total of 93.7% (95% CI: 92.9-94.6%) of 3119 Chinese residents were willing to receive a third dose of the COVID-19 vaccine. Individuals with low level of perceived susceptibility, perceived benefit, cues to action cues, and high level of perceived barriers, old age, low educational level, low monthly household income, and low knowledge score on COVID-19 were less likely to have the acceptance of a third dose of COVID-19 (all p < 0.05). In the multivariable logistic regression model, acceptance of the third dose of COVID-19 vaccine was mainly related to previous vaccination history [Sinopharm BBIP (aOR = 6.55, 95% CI 3.30-12.98), Sinovac (aOR = 5.22, 95% CI:2.72-10.02), Convidecia (aOR = 5.80, 95% CI: 2.04-16.48)], high level of perceived susceptibility (aOR = 2.48, 95% CI: 1.48-4.31) and high level of action cues (aOR = 23.66, 95% CI: 9.97-56.23). Overall, residents in China showed a high willingness to accept the third dose of COVID-19 vaccines, which can help vaccine manufacturers in China to manage the vaccine production and distribution for the huge domestic and international vaccine demand. Relevant institutions could increase people's willingness to booster shots by increasing initial COVID-19 vaccination rates, public's perception of COVID-19 susceptibility and cues to action through various strategies and channels. Meanwhile, it also has certain reference significance for other countries to formulate vaccine promotion strategies. SN - 2076-393X UR - https://www.unboundmedicine.com/medline/citation/35062750/Acceptance_of_a_Third_Dose_of_COVID_19_Vaccine_and_Associated_Factors_in_China_Based_on_Health_Belief_Model:_A_National_Cross_Sectional_Study_ DB - PRIME DP - Unbound Medicine ER -
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