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Effects of ofloxacin on the structure and function of freshwater microbial communities.
Aquat Toxicol. 2022 Mar; 244:106084.AT

Abstract

Ofloxacin (OFL) is a broad-spectrum fluoroquinolone antibiotic frequently used in clinic for treating bacterial infections. The discharged OFL would inevitably enter into aquatic ecosystems, affecting the growth of non-target microorganisms, which may result in micro-ecosystem imbalance. To the best of our knowledge, researches in this area are rather sparse. The present study evaluated the response of photosynthetic microorganisms (cyanobacteria, eukaryotic algae) and aquatic microbial community to OFL in a microcosm. Results showed that ofloxacin presented an inhibitory effect on the growth Microcystis aeruginosa. Although 0.1 mg/L OFL has no significant impact on alpha diversity of the microbial communities, it obviously altered the structure and decreased the species interaction of prokaryotic community by reducing the capacities of nitrogen fixation, photosynthetic and metabolic capacity of the microbial community. This study pointed out that the residual OFL in water would disturb the balance of the aquatic micro-ecology, suggesting that more attentions should be given to the negative effects of antibiotics and other bioactive pollutants on aquatic environments.

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Publisher Full Text (DOI)

Authors+Show Affiliations

College of Environment, Zhejiang University of technology, Hangzhou 310032, P.R. China.

Faculty of Bioscience Engineering, Ghent University Campus Kortrijk, Graaf Karel de Goedelaan 5, 8500 Kortrijk, Belgium.

College of Environment, Zhejiang University of technology, Hangzhou 310032, P.R. China.

College of Environment, Zhejiang University of technology, Hangzhou 310032, P.R. China.

College of Environment, Zhejiang University of technology, Hangzhou 310032, P.R. China.

College of Environment, Zhejiang University of technology, Hangzhou 310032, P.R. China.

College of Environment, Zhejiang University of technology, Hangzhou 310032, P.R. China.

College of Environment, Zhejiang University of technology, Hangzhou 310032, P.R. China. Electronic address: lutao@zjut.edu.cn.

College of Environment, Zhejiang University of technology, Hangzhou 310032, P.R. China.

MeSH

Fresh WaterMicrobiotaMicrocystisOfloxacinWater Pollutants, Chemical

Pub Type(s)

Journal Article

Language

eng

PubMed ID

35078055

Citation

Deng, Yu, et al. "Effects of Ofloxacin On the Structure and Function of Freshwater Microbial Communities." Aquatic Toxicology (Amsterdam, Netherlands), vol. 244, 2022, p. 106084.

Deng Y, Debognies A, Zhang Q, et al. Effects of ofloxacin on the structure and function of freshwater microbial communities. Aquat Toxicol. 2022;244:106084.

Deng, Y., Debognies, A., Zhang, Q., Zhang, Z., Zhou, Z., Zhang, J., Sun, L., Lu, T., & Qian, H. (2022). Effects of ofloxacin on the structure and function of freshwater microbial communities. Aquatic Toxicology (Amsterdam, Netherlands), 244, 106084. https://doi.org/10.1016/j.aquatox.2022.106084

Deng Y, et al. Effects of Ofloxacin On the Structure and Function of Freshwater Microbial Communities. Aquat Toxicol. 2022;244:106084. PubMed PMID: 35078055.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - Effects of ofloxacin on the structure and function of freshwater microbial communities. AU - Deng,Yu, AU - Debognies,Andries, AU - Zhang,Qi, AU - Zhang,Zhenyan, AU - Zhou,Zhigao, AU - Zhang,Jinfeng, AU - Sun,Liwei, AU - Lu,Tao, AU - Qian,Haifeng, Y1 - 2022/01/20/ PY - 2021/10/25/received PY - 2022/01/17/revised PY - 2022/01/18/accepted PY - 2022/1/26/pubmed PY - 2022/2/16/medline PY - 2022/1/25/entrez KW - Antibiotic contamination KW - Aquatic microbiome KW - Cyanobacterial blooms KW - Ecotoxicity KW - Freshwater algae SP - 106084 EP - 106084 JF - Aquatic toxicology (Amsterdam, Netherlands) JO - Aquat Toxicol VL - 244 N2 - Ofloxacin (OFL) is a broad-spectrum fluoroquinolone antibiotic frequently used in clinic for treating bacterial infections. The discharged OFL would inevitably enter into aquatic ecosystems, affecting the growth of non-target microorganisms, which may result in micro-ecosystem imbalance. To the best of our knowledge, researches in this area are rather sparse. The present study evaluated the response of photosynthetic microorganisms (cyanobacteria, eukaryotic algae) and aquatic microbial community to OFL in a microcosm. Results showed that ofloxacin presented an inhibitory effect on the growth Microcystis aeruginosa. Although 0.1 mg/L OFL has no significant impact on alpha diversity of the microbial communities, it obviously altered the structure and decreased the species interaction of prokaryotic community by reducing the capacities of nitrogen fixation, photosynthetic and metabolic capacity of the microbial community. This study pointed out that the residual OFL in water would disturb the balance of the aquatic micro-ecology, suggesting that more attentions should be given to the negative effects of antibiotics and other bioactive pollutants on aquatic environments. SN - 1879-1514 UR - https://www.unboundmedicine.com/medline/citation/35078055/Effects_of_ofloxacin_on_the_structure_and_function_of_freshwater_microbial_communities_ DB - PRIME DP - Unbound Medicine ER -