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High-dose pyridoxine in tardive dyskinesia.
J Clin Psychiatry 1978; 39(6):573-5JC

Abstract

The clinical similarities of tardive dyskinesia and 1-dopa intoxication lend support to the post-synaptic hypersensitivity hypothesis in tardive dyskinesia. Pyridoxine, a co-factor in the decarboxylation of dopa, reverses the movement disorder of l-dopa intoxication. Although early studies of pyridoxine in tardive dyskinesia have not been encouraging, the results of the present study suggest that high doses of pyridoxine may reduce the frequency and severity of involuntary movements in tardive dyskinesia.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Clinical Trial
Journal Article

Language

eng

PubMed ID

350860

Citation

DeVeaugh-Geiss, J, and L Manion. "High-dose Pyridoxine in Tardive Dyskinesia." The Journal of Clinical Psychiatry, vol. 39, no. 6, 1978, pp. 573-5.
DeVeaugh-Geiss J, Manion L. High-dose pyridoxine in tardive dyskinesia. J Clin Psychiatry. 1978;39(6):573-5.
DeVeaugh-Geiss, J., & Manion, L. (1978). High-dose pyridoxine in tardive dyskinesia. The Journal of Clinical Psychiatry, 39(6), pp. 573-5.
DeVeaugh-Geiss J, Manion L. High-dose Pyridoxine in Tardive Dyskinesia. J Clin Psychiatry. 1978;39(6):573-5. PubMed PMID: 350860.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - High-dose pyridoxine in tardive dyskinesia. AU - DeVeaugh-Geiss,J, AU - Manion,L, PY - 1978/6/1/pubmed PY - 1978/6/1/medline PY - 1978/6/1/entrez SP - 573 EP - 5 JF - The Journal of clinical psychiatry JO - J Clin Psychiatry VL - 39 IS - 6 N2 - The clinical similarities of tardive dyskinesia and 1-dopa intoxication lend support to the post-synaptic hypersensitivity hypothesis in tardive dyskinesia. Pyridoxine, a co-factor in the decarboxylation of dopa, reverses the movement disorder of l-dopa intoxication. Although early studies of pyridoxine in tardive dyskinesia have not been encouraging, the results of the present study suggest that high doses of pyridoxine may reduce the frequency and severity of involuntary movements in tardive dyskinesia. SN - 0160-6689 UR - https://www.unboundmedicine.com/medline/citation/350860/High_dose_pyridoxine_in_tardive_dyskinesia_ L2 - http://www.diseaseinfosearch.org/result/6999 DB - PRIME DP - Unbound Medicine ER -