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Vaginitis: current microbiologic and clinical concepts.
CMAJ. 1986 Feb 15; 134(4):321-31.CMAJ

Abstract

Infectious vaginitis occurs when the normal vaginal flora is disrupted; it may arise when saprophytes overwhelm the host immune response, when pathogenic organisms are introduced into the vagina or when changes in substrate allow an imbalance of microorganisms to develop. Examples of these types of vaginitis include the presence of chronic fungal infection in women with an inadequate cellular immune response to the yeast, the introduction of trichomonads into vaginal epithelium that has a sufficient supply of glycogen, and the alteration in bacterial flora, normally dominated by Lactobacillus spp., and its metabolites that is characteristic of "nonspecific vaginitis". The authors review microbiologic and clinical aspects of the fungal, protozoal and bacterial infections, including the interactions of bacteria thought to produce nonspecific vaginitis, that are now recognized as causing vaginitis. Other causes of vaginitis are also discussed.

Links

PMC Free PDF

Authors

Hill LV
No affiliation info available
Embil JA
No affiliation info available

MeSH

Antibody FormationAntifungal AgentsCandidiasisCandidiasis, VulvovaginalCarrier StateFemaleGardnerella vaginalisHaemophilus InfectionsHumansLactobacillusMaleMetronidazoleMycoplasma InfectionsNystatinPregnancyPregnancy Complications, InfectiousSexual BehaviorStreptococcal InfectionsStreptococcus agalactiaeTrichomonas VaginitisVaginaVaginitisVirus Diseases

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

3510698

Citation

Hill, L V., and J A. Embil. "Vaginitis: Current Microbiologic and Clinical Concepts." CMAJ : Canadian Medical Association Journal = Journal De l'Association Medicale Canadienne, vol. 134, no. 4, 1986, pp. 321-31.
Hill LV, Embil JA. Vaginitis: current microbiologic and clinical concepts. CMAJ. 1986;134(4):321-31.
Hill, L. V., & Embil, J. A. (1986). Vaginitis: current microbiologic and clinical concepts. CMAJ : Canadian Medical Association Journal = Journal De l'Association Medicale Canadienne, 134(4), 321-31.
Hill LV, Embil JA. Vaginitis: Current Microbiologic and Clinical Concepts. CMAJ. 1986 Feb 15;134(4):321-31. PubMed PMID: 3510698.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Vaginitis: current microbiologic and clinical concepts. AU - Hill,L V, AU - Embil,J A, PY - 1986/2/15/pubmed PY - 1986/2/15/medline PY - 1986/2/15/entrez SP - 321 EP - 31 JF - CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne JO - CMAJ VL - 134 IS - 4 N2 - Infectious vaginitis occurs when the normal vaginal flora is disrupted; it may arise when saprophytes overwhelm the host immune response, when pathogenic organisms are introduced into the vagina or when changes in substrate allow an imbalance of microorganisms to develop. Examples of these types of vaginitis include the presence of chronic fungal infection in women with an inadequate cellular immune response to the yeast, the introduction of trichomonads into vaginal epithelium that has a sufficient supply of glycogen, and the alteration in bacterial flora, normally dominated by Lactobacillus spp., and its metabolites that is characteristic of "nonspecific vaginitis". The authors review microbiologic and clinical aspects of the fungal, protozoal and bacterial infections, including the interactions of bacteria thought to produce nonspecific vaginitis, that are now recognized as causing vaginitis. Other causes of vaginitis are also discussed. SN - 0820-3946 UR - https://www.unboundmedicine.com/medline/citation/3510698/Vaginitis:_current_microbiologic_and_clinical_concepts_ DB - PRIME DP - Unbound Medicine ER -