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Hyperuricemia and gout.
Med Clin North Am. 1986 Mar; 70(2):419-36.MC

Abstract

Gout is a clinical syndrome encompassing a group of metabolic diseases that are all characterized by abnormal uric acid metabolism. In its fullest form, gout is defined by: an increase in the serum urate concentration; characteristic, recurrent, acute arthritic attacks, with monosodium urate monohydrate crystals demonstrable in synovial fluid leukocytes; tophi, usually in and around joints of the extremities, composed of monosodium urate monohydrate deposits; renal disease, often accompanied by hypertension with glomerular, tubular, interstitial, and vascular involvement; and uric acid nephrolithiasis. Any combination of these manifestations may occur, although tophi and urate nephropathy rarely antedate gouty arthritis.

Authors

German DC
No affiliation info available
Holmes EW
No affiliation info available

MeSH

Acute DiseaseAdultAllopurinolAnti-Inflammatory AgentsArthritisArthrographyCalcinosisChronic DiseaseColchicineFemaleGoutHumansKidney CalculiKidney DiseasesMiddle AgedProbenecidUric Acid

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

3512932

Citation

German, D C., and E W. Holmes. "Hyperuricemia and Gout." The Medical Clinics of North America, vol. 70, no. 2, 1986, pp. 419-36.
German DC, Holmes EW. Hyperuricemia and gout. Med Clin North Am. 1986;70(2):419-36.
German, D. C., & Holmes, E. W. (1986). Hyperuricemia and gout. The Medical Clinics of North America, 70(2), 419-36.
German DC, Holmes EW. Hyperuricemia and Gout. Med Clin North Am. 1986;70(2):419-36. PubMed PMID: 3512932.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hyperuricemia and gout. AU - German,D C, AU - Holmes,E W, PY - 1986/3/1/pubmed PY - 1986/3/1/medline PY - 1986/3/1/entrez SP - 419 EP - 36 JF - The Medical clinics of North America JO - Med Clin North Am VL - 70 IS - 2 N2 - Gout is a clinical syndrome encompassing a group of metabolic diseases that are all characterized by abnormal uric acid metabolism. In its fullest form, gout is defined by: an increase in the serum urate concentration; characteristic, recurrent, acute arthritic attacks, with monosodium urate monohydrate crystals demonstrable in synovial fluid leukocytes; tophi, usually in and around joints of the extremities, composed of monosodium urate monohydrate deposits; renal disease, often accompanied by hypertension with glomerular, tubular, interstitial, and vascular involvement; and uric acid nephrolithiasis. Any combination of these manifestations may occur, although tophi and urate nephropathy rarely antedate gouty arthritis. SN - 0025-7125 UR - https://www.unboundmedicine.com/medline/citation/3512932/Hyperuricemia_and_gout_ DB - PRIME DP - Unbound Medicine ER -